A medium processing device (10) for which a subsequently loaded storage cassette (19C) is equipped with: a first cassette-side guide (82) that makes contact with a first slot-side guide (42) and gradually restricts the loading posture of the subsequently loaded storage cassette (19C), when the cassette is loaded into a slot (28); a second cassette-side guide (52) that, after the first cassette-side guide (82) has made contact with the first slot-side guide (42), makes contact with a second slot-side guide (52), and gradually restricts the loading posture of the subsequently loaded storage cassette (19C), when the cassette is loaded into the slot (28); a cassette-side connector (93) that is electrically connected to a slot-side connector (38) when the cassette has been loaded into the subsequent loading positon in the slot (28); and a third cassette-side guide (46) that, when the subsequently loaded storage cassette (19C) has been loaded into the subsequent loading position, approaches or makes contact with a third slot-side guide (46), thereby inhibiting rotation of the cassette-side connector (93) around the center of gravity of the subsequently loaded storage cassette (19C), in the direction in which the cassette-side connector separates from the slot-side connector (38).