30results about How to "High specific selectivity" patented technology

The invention discloses a polypeptide capable of specifically targeting triple negative breast cancer cells and the application of the polypeptide. The polypeptide has the amino acid sequence shown in any one of SEQ ID No.1 to SEQ ID No.5. The polypeptide provided by the embodiment of the present invention has high specificity and affinity to triple-negative breast cancer cells, but has relatively weak binding ability to other types of breast cancer cells, showing high specificity for triple-negative breast cancer cells, It can be used for targeted therapy or imaging diagnosis of triple-negative breast cancer.

The invention discloses a polypeptide capable of specifically targeting triple-negative breast cancer stem cells and the application of the polypeptide. The polypeptide has the amino acid sequence shown in any one of SEQ ID No.1 to SEQ ID No.3. The polypeptide provided by the embodiment of the present invention has high specificity and affinity with triple-negative breast cancer stem cells, but has relatively weak binding ability with other types of breast cancer cells, showing high specificity for triple-negative breast cancer stem cells, It can be used for targeted therapy or imaging diagnosis of triple-negative breast cancer.

The invention discloses a surface-enhanced Raman spectrum detection method for melamine and formaldehyde. The formaldehyde SERS substrate of the invention has specific selectivity, high sensitivity, signal stability and reproducibility. The preparation method of the formaldehyde SERS substrate is simple, the cost is low, and the detection kit made into it is convenient to carry and store. In the SERS detection method of melamine and formaldehyde, two substrates are used, and the detection of melamine and formaldehyde can be realized by preparing the test solution once.

The invention discloses a preparation method of carbofuran molecularly imprinted microspheres, comprising the following steps of: dissolving template molecules and a functional monomer into a pore-forming agent solution containing a cross-linking agent and an initiator so as to obtain a reaction mixture, carrying out ultrasonic degassing, sparging nitrogen for deoxygenation, carrying out polymerization in a sealed state, carrying out centrifugation after complete reaction so as to obtain a white powdery polymer, carrying out Soxhlet extraction respectively by the adoption of a methanol acetate mixed liquor and methanol as extraction solvents, drying under vacuum, and removing the solvents so as to obtain the carbofuran molecularly imprinted microspheres. The invention also discloses the carbofuran molecularly imprinted microspheres prepared by the preparation method and an application thereof. The carbofuran molecularly imprinted microspheres obtained in the invention has specific selectivity for carbofuran in agricultural products, can be used to detect residual pesticides on agricultural products rapidly, sensitively, accurately and efficiently, and also can be used as a solid-phase extraction filler.