The invention discloses an energy consumption control system and method for area buildings, relating to the technical field of comprehensive building energy consumption control. The system comprises a distributed video sensor unit, machine vision recognition unit, a distributed comfort sensor unit, a subarea information fusion unit, a single building control unit and an area control center unit, wherein the distributed video sensor unit comprises a plurality of video sensors distributed in different subareas in one building, the machine vision recognition unit is connected with the distributed video sensor unit, the distributed comfort sensor unit comprises a plurality of comfort sensors distributed in different subareas in the one building, the subarea information fusion unit is used for generating a distribution control demand of each subarea in the one building, the single building control unit is used for generating the control demand of the one building, and the area control center unit is used for performing area energy consumption balance and optimization to generate control information. The system provided by the invention can be used for realizing area energy consumption balance and optimization, energy consumption balance and optimization of buildings and consumption balance and optimization of cold and heat sources and a tail end so as to finally obtain the optimal point of balance between comfort and energy consumption and reduce the energy consumption and carbon emission of area buildings.