The present invention provides an anti-interference encoding algorithm for low-frequency acoustic wave communication data transmission, including determining available encoding frequency points: 1100HZ, 1200HZ, 1300HZ, 1400HZ, 1500HZ, 1600HZ, 1700HZ, 1800HZ, 1900HZ, 2000HZ, 2100HZ, 2200HZ, 2300HZ, 2400HZ, 2500HZ, 2600HZ, 2700HZ, 2800HZ, 2900HZ a total of 19 frequency resources, the interval between each coding frequency point is 100HZ; according to the determined 19 frequency point resources, use three coding frequency point mixed coding, and fix the middle coding The frequency points are: 1800HZ, 1900HZ, 2000HZ; the three encoded sound wave encoding frequency points adopt the same energy decibel value; according to the encoding rules, the specific encoding combination value can be obtained, which can greatly improve the transmission reliability in a more complex sound environment and reduce the The probability of being disturbed by the environment improves the accuracy of transmission and thus improves the efficiency, and provides a reliable, practical, and low-cost means of small-volume data communication in applications where sound sending and receiving equipment is relatively cheap.