The invention discloses a positively-biased multidirectional three-dimensional connected clamp plate link, a quick-release frame, an application and a method of the positively-biased multidirectional three-dimensional connected clamp plate link and the quick-release frame. The clamp plate link comprises a knob core, a clamp plate, a clamp ring and a knob pin, and is an independent connecting piece capable of simultaneously realizing forwardly, obliquely and multidirectional connecting or concentrically connecting in a same point way; the quick-release frame is a planar frame or a three-dimensional frame formed by mutually assembling an upright bar, a flat bar and an oblique bar; the clamp plate link and the quick-release frame can be applied to a carrying frame, a bailey frame, a bridge frame, a storage rack, a frame, a crane carriage, an elevator frame, a suspension frame, a lifting frame and a carrying frame to be quickly dismounted, especially a scaffold, a template support and the like in the engineering construction field; the independent nodes and independent rod pieces of the quick-release frame can be realized in a solderless manufacturing and pin fixed connection way, the same-point, same-node, coplanar and concentric connection can be realized, the multi-directional bearing, flexibility and diversity and variation can be realized; in addition, the clamp plate link is safe and convenient, firm and durable, accurate and quick.