The invention discloses a wearable type flexible temperature-difference power generation structure with a stretchable wire. The structure comprises a flexible thermal conductive
silica gel cushion, a temperature-difference power generation layer, a thermal conductive patch and a
metal cooling fin from the wearable surface to outside in sequence; the cold end plane and the hot end plane of the temperature-difference power generation layer are connected with the bottom surface of the thermal conductive patch and the upper surface of the flexible thermal conductive
silica gel cushion respectively; and the upper surface of the thermal conductive patch is connected with the bottom surface of the
metal cooling fin. When the wearable surface is adhered to non-planar
human body skin, the stretchable wire and a
polydimethylsiloxane package absorb deformation stress so as to avoid
cracking of a
bismuth telluride based thermoelectric arm with a poor mechanical performance and to avoid failure of
electrode connection; the flexible thermal conductive
silica gel cushion is packaged on one side of the hot end of the temperature-difference power generation layer, so that the tight contact with the
skin of a user is ensured, and the
heat transfer efficiency is improved; the cold end of each rigid temperature-difference power generation module is equipped with the independent thermal conductive patch and
metal cooling fin, so that the structural thickness and quality are reduced and the
temperature difference between the cold end and the hot end is increased; and in addition, the wearable type flexible temperature-difference power generation structure can be used for supplying power to wearable type medical apparatuses and has the value of popularization and application.