The invention relates to an adansonia digitata seed oil baby moisturizing and anti-chapping cream. The cream comprises the following raw materials according to weight percentages: 13.5-48 parts of a phase-A component, 46.2-76.5 parts of a phase-B component, and 0.63-6.8 parts of a phase-C component, wherein the phase-A component comprises polyglycerol stearate, cetostearyl alcohol, plant bionic sebum, colorless jojoba oil, adansonia digitata seed oil, stearic acid, camellia oil, sitostanol, cyclopentasiloxane, polydimethylsiloxane, bisabolol, and vitamin E; the phase-B component comprises water, glycerinum, EDTA-2Na, allantoin, carbomer 940, polyethylene glycol-14M, and hyaluronic acid; and the phase-C component comprises glucosan, oat alkaloid, capryloyl hydroxamic acid, ethylhexylglycerin, 1,2-hexanediol, 1,3-butanediol, and arginine. The invention further discloses a preparation method of the cream. The cream and the preparation method thereof provided by the invention have the advantages that the cream has the moisturizing effect and can prevent chapping in a safe and mild manner, so as to be used as a baby skincare product.