99 results about "Alcoholic drinking" patented technology

The invention discloses a genetically engineered probiotic composition for expressing ADH (adenosine dihydrogenase) and ALDH (aldehyde dehydrogenase) and application of the genetically engineered probiotic composition in hangover alleviating and liver protection. The genetically engineered probiotic composition (such as EcN.1917-ADH and EcN.1917-ALDH) is constructed by introducing genes of alcohol dehydrogenase (ADH, NCBI (National Center for Biotechnology Information) Gene ID: 855349) and acetaldehyde dehydrogenase (ALDH, NCBI Gene ID: 855206) of saccharomyces cerevisiae into probiotics (such as escherichia coli). The engineering bacterium shows remarkable ethanol, acetaldehyde and endurance capacity in an in-vitro experiment, and the ethanol degradation rate is remarkably higher than that of a wild type strain; a mouse drunkenness model verifies that drunkenness and death caused by drinking can be reduced through pretreatment, drunkenness tolerance time is remarkably prolonged, and movement coordination disorder caused by alcohol can be improved. The strain can effectively promote alcohol metabolism and relieve alcoholic liver injury, and a new candidate strain is provided for development of a hangover-alleviating and liver-protecting viable bacterial preparation.

The invention belongs to the technical field of automobile safety, and discloses an automobile drunk driving prevention system and method based on passenger state and air alcohol detection, an alcohol concentration detection module comprises an alcohol sensor in a driver area and an alcohol sensor in a public area / passenger area in an automobile; the passenger state detection module comprises a seat sensor and a camera; the central control unit is mounted below a vehicle instrument panel; the active expiration reinspection module is integrated in a steering wheel scheme, or is designed into an independent small handheld or fixed mouthpiece; the actuator is connected to an original start button circuit, a transmission control unit (TCU) or an engine control unit (ECU) of a vehicle through a relay or a control signal wire harness and sends a'start / operation limiting 'instruction. The early warning device utilizes an original instrument panel display system, a horn system and a sound system of the vehicle. According to the invention, passenger positioning and specific area alcohol concentration monitoring are integrated, and the risk of passenger drinking misjudgment caused by only depending on the overall concentration in the vehicle is greatly reduced.

The invention discloses an anti-drunkenness composition and application thereof. The invention provides an application of a composition in preparation of an anti-drunkenness product, the composition contains edible plasma powder, xylitol, fructo-oligosaccharide, microcrystalline cellulose, mogroside and magnesium stearate, and the edible plasma powder contains immune globulin IgG. The TZK provided by the invention has obvious regulation and improvement effects on sleep behaviors, serum indexes and gastrointestinal injury after acute drinking. The oxidative stress state after long-term large-dose chronic drinking is effectively adjusted, so that the oxidative stress injury index malondialdehyde (MDA) gradually returns to the normal level; according to the present invention, the activity of the liver injury markers such as alanine transaminase (ALT) and aspartate transaminase (AST) is reduced, the liver protection effect is provided, and the gastric mucosa structure repair is promoted by increasing the gastric mucosa prostaglandin content and reducing the local MDA level;

The invention discloses an extraction process method of a functional gastrodia elata wine partner and application of the functional gastrodia elata wine partner in alcoholic liver injury, and belongs to the technical field of biology. In order to improve the diversity of edible gastrodia elata products and solve the problems of long consumed time, low solubility, low leaching rate of active substances and the like of traditional gastrodia elata wine, the invention provides a new concept of gastrodia elata wine partners. Artificial intelligence and a response surface are combined, and optimal extraction process parameters are optimized and obtained as follows: the volume fraction of ethanol is 50%, the material-liquid ratio is 1: 20 g / mL, the ultrasonic time is 1.55 h, the ultrasonic temperature is 58 DEG C, and the ultrasonic power is 490 W; network pharmacology and molecular docking reveal that the gastrodia elata wine partner has a potential protection effect on alcoholic liver diseases; cell tests show that the gastrodia elata wine partner has a remarkable protection effect on HegG2 cells, and animal experiments further reveal that the gastrodia elata wine partner can effectively reduce the ethanol content of rat eye socket blood and has potential advantages in the aspects of reducing free radical damage and improving the oxidative stress state. The convenient edible product and the matching mode are expected to become beneficial supplement of the modern drinking culture, and the liver health is protected while people enjoy delicious wine.

The application provides a user drinking amount intervention management method and related equipment applied to the technical field of data processing. The application processes drinking purpose information of a target user and real-time physiological state information of the target user to generate a drinking training factor; processes a recent medical examination report information of the target user to generate an initial drinking amount of the target user and an initial limit drinking amount of the target user; processes identity information of the target user and the real-time physiological state information of the target user to generate a drinking amount adjustment factor; processes the initial drinking amount of the target user and the initial limit drinking amount of the target user based on the drinking amount adjustment factor to generate a target drinking amount of the target user and a target limit drinking amount of the target user; processes the target drinking amount of the target user and the target limit drinking amount of the target user based on the drinking training factor to generate drinking feedback information of the target user and processes the drinking feedback information to generate early warning threshold information.

A Limosilactobacillus fermentum strain capable of alleviating a hangover and the use thereof. The strain is at least one strain of Limosilactobacillus fermentum ibiome020, Limosilactobacillus fermentum ibiome021 and Limosilactobacillus fermentum ibiome022 respectively deposited with deposit numbers of CCTCC NO: M 2024188, CCTCC NO: M 2024222 and CCTCC NO: M 2024189. The Limosilactobacillus fermentum is a natural bacterium derived from the intestine of a healthy human and has high safety; can alleviate chronic / acute alcoholism, alcoholic intestinal damage or alcoholic liver damage; can accelerate the metabolism of ethanol and / or acetaldehyde, and delay the onset of intoxication; can shorten the sobering-up time; can reduce the mortality caused by drinking alcohol; can reduce the liver index; can lower the level of AST and / or ALT in serum; can alleviate discomfort caused by ethanol and / or acetaldehyde, and mitigate symptoms such as dizziness, headache, nausea and vomiting, and hangover after drinking alcohol; can ameliorate oxidative stress caused by alcohol, and increase the level of GSH in the liver; and also has excellent resistance to gastrointestinal fluid and bile salt, and can adapt to the complex environment within the body.

Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non- alcoholic fatty liver disease (NAFLD), is a condition characterized by the accumulation of fat in the liver of individuals with no alcohol consumption, and at least one cardiometabolic risk factor (overweight / obesity, high blood pressure, high blood sugar, high triglycerides levels, low HDL-C levels). The inventors demonstrated that Rab30 silencing improve metabolic dysfunction–associated steatotic liver disease (MASLD). The present invention relates to a method for the treatment of metabolic dysfunction–associated steatotic liver disease (MASLD) in a subject in need thereof comprising the administration of a therapeutically effective amount of an inhibitor of Rab30.

1. Name of the product in this design: Wine Glass (Four Seasons Flow). 2. Purpose of this design: A cup for drinking alcohol. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses a ceramic wine container capable of increasing the content of nutrient elements in a wine body and improving the quality of white wine as well as a preparation method and application, and belongs to the technical field of wine containers. The invention provides a ceramic wine container capable of increasing the content of nutrient elements in a wine body and improving the quality of white wine. The ceramic wine container is prepared from the following raw materials: an additive material and argil, the additive materials comprise a first group of materials, a second group of materials and a third group of materials. According to the invention, the ceramic wine container is obtained by using a quenching technology of compatibility of three materials and nutritional ingredients, and the wine body is subjected to secondary fermentation by using the ceramic wine container, so that harmful substances such as miscellaneous aldehyde, methanol and the like in the wine can be remarkably reduced, the contents of minerals, trace elements and nutritional ingredients are increased, and the burden of drinking on the liver and the stomach is relieved. In the drinking process, all nutrient elements can be wrapped by alcohol and rapidly enter blood, cell regeneration is promoted, and the immunity is improved. The sensory quality of the drinks in the mouth can be improved, the cellaring time is remarkably shortened, the production efficiency is improved, and the production cost is reduced.

The invention relates to the technical field of compatibility of traditional Chinese medicines, in particular to a tetracera tenuifolia liver-protecting tablet as well as a preparation method and application thereof. The tetracera tetracera liver protection tablet is prepared from the following raw materials in parts by mass: 5 to 20 parts of tetracera tetracera, 40 to 60 parts of herba verbenae, 40 to 60 parts of ixeris chinensis, 3 to 15 parts of fructus gardeniae and 23.4 to 61.8 parts of auxiliary materials. The invention provides an oral administration mode for people with alcoholic liver injury. Compared with injections, powder injections and other dosage forms, the pharmaceutical composition has the remarkable advantages of being convenient to use and easy to take. The traditional Chinese medicine composition is especially suitable for people who cannot avoid drinking in long-term life and have alcoholic liver injury, the long-term use requirement of the traditional Chinese medicine composition is met, the medication problem of specific people on liver injury is effectively solved, and a new choice is brought to the field of liver injury treatment.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for improving alcohol tolerance of a user and relieving uncomfortable symptoms of the user after drinking. Compared with modern medical treatment, the traditional Chinese medicine compound is started from multiple mechanisms of relieving alcoholism, protecting liver and stomach and dredging collaterals and blood stasis, whole-course intervention from acute symptom control to organ injury repair is achieved, and the traditional Chinese medicine compound is more suitable for the complex pathogenesis of alcoholism multi-system injury. According to the formula, an effective traditional Chinese medicine scheme is provided for drunkenness patients according to the core treatment principle of separately eliminating and draining, and clearing away heat and toxic materials. The composition can significantly improve the alcohol tolerance of a user, alleviate the vomiting symptom of the user after drinking, and improve the discomfort symptom of the user after sobering up. The traditional Chinese medicine composition is a pure traditional Chinese medicine formula, is safe and has no toxic or side effect.

1. Name of the product in this design: Intelligent storage cabinet for vehicle keys. 2. Purpose of this design: For storing vehicle keys; the storage cabinet identifies the characteristics of the people storing and retrieving vehicle keys to determine whether they have been drinking alcohol; thus effectively preventing drivers from driving under the influence of alcohol. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses an equipment fault diagnosis method based on big data analysis, and relates to the technical field of drinking or drug taking detection, and the method comprises the following steps: S101, collecting the operation state information, including sensor response information and sensor resistance information, of a skin resistance sensor in a driving state rapid detection system, and after collection, sending the information to a database; and processing sensor response information and sensor resistance information when the skin resistance sensor operates. The running state of the skin resistance sensor in the driving state rapid detection system is monitored, abnormal hidden dangers of the running state of the skin resistance sensor are effectively prevented, and therefore the situation that the accuracy and reliability of the system are affected due to the fact that the skin resistance sensor generates wrong measurement results is effectively prevented; therefore, the system cannot reliably detect drunk driving and toxic driving behaviors, and cannot provide accurate alarms or trigger corresponding safety measures.

A drink assembly including a vessel having an open top and a bottom and a lid assembly removably connected to the vessel. The lid assembly includes a lid body and a mouthpiece extending upwardly from the lid body. The mouthpiece includes a mouthpiece body having an upper end that is sized for use without requiring, or with only minimal, puckering of the lips. The upper end includes a first rim portion including simple curvature and a second rim portion opposite the first rim portion and including a contour defined by a compound curve. The mouthpiece further including a through hole extending through the mouthpiece body and fluidly coupled to the vessel.

An alcohol consumption inference device (100) comprises a current information acquisition unit (110) that acquires, in a time series, current information which contains biological data regarding a subject being observed, a reference output unit (130) that uses the current information accumulated in a time series manner and current information at a current time to output a reference value which indicates a feature amount for a presumably sober state during a time period determined on the basis of the current information at the current time, a current state inference unit (170) that uses the reference value for the time period determined on the basis of the current information at the current time and the current information at the current time to output a feature amount for an alcohol consumption state at the current time, and an alcohol consumption state determination unit (180) that outputs, on the basis of the feature amount for the alcohol consumption state output by the current state inference unit, the result of determination regarding the alcohol consumption state of the subject being observed.

This invention provides a composition of agarwood and mugwort, its preparation method, and its application in hangover remedies, relating to the field of plant extraction technology. The hangover remedy prepared from the agarwood and mugwort composition obtained by the extraction method of this invention has excellent hangover-relieving and liver-protecting effects for patients with excessive drinking or alcohol poisoning, improving the discomfort symptoms caused by excessive drinking. The hangover remedy containing the agarwood and mugwort composition prepared by this invention accelerates the metabolism of ethanol in the liver by reducing malondialdehyde content and increasing the activity of alcohol dehydrogenase and glutathione, thus achieving the effects of relieving hangovers, protecting the liver, and alleviating hangovers. Simultaneously, the aroma of agarwood and mugwort also has a calming and soothing effect, relieving tension, anxiety, and other emotional states caused by drinking.

To provide a karaoke device capable of assisting a user to perform karaoke singing well.SOLUTION: In the karaoke device, a karaoke body 10 includes an acquisition part for acquiring an alcohol concentration of exhalation of a user, a scoring processing part for evaluating karaoke singing performed by the user and obtaining a score value, and a first storage processing part for storing user identification information of the user, musical piece identification information of a musical piece, the score value of the karaoke singing, and the alcohol concentration acquired during the karaoke singing in association with one another. And a control unit including a second storage processing unit that stores a music piece as a sober-time high score music piece in a case where a score value of a drinking state is lower than a score value of a sober state, and a presentation unit that presents a message recommending drinking in a case where a music piece selected by a user is a drinking-time high score music piece and presents a message suppressing drinking in a case where the music piece selected by the user is the sober-time high score music piece.SELECTED DRAWING: Figure 2

The invention belongs to the technical field of chemical analysis and detection, and particularly relates to a method for detecting higher alcohols in serum and application of the method in metabolic kinetic analysis of alcoholic beverages. In order to realize the effective separation and synchronous detection of fatty alcohol, aromatic alcohol and isomers thereof, reduce the volatile loss of higher alcohol and the use amount of a sample and reduce the serum matrix effect, the method comprises the following steps: performing pretreatment extraction and derivatization on drunk serum; high performance liquid chromatography-triple quadrupole mass spectrometry is adopted to detect higher alcohols in serum after drinking and the content of the higher alcohols. Results prove that the detection method disclosed by the invention has the advantages of low sample amount, high precision and accuracy, low matrix effect and low detection limit. The detection method disclosed by the invention is used for detecting the content of ethanol and higher alcohol in serum in the metabolic kinetics analysis of the alcoholic beverage, so that the alcoholic beverage with excellent metabolic efficiency can be screened, and data support can be provided for the evaluation of slow drunkenness, fast sobering and light hangover.

An alcohol consumption detection device (100) according to the present disclosure comprises: an alcohol consumption fluctuation information acquisition unit (110) that acquires alcohol consumption fluctuation information that indicates information about a subject, the information fluctuating due to a alcohol consumption of the subject; an over-detection factor information acquisition unit (120) that acquires over-detection factor information that indicates information about the factor of the fluctuation of the alcohol consumption fluctuation information and a factor other than the alcohol consumption of the subject; and an alcohol consumption detection unit (130) that estimates the alcohol consumption state of the subject on the basis of the alcohol consumption fluctuation information and the over-detection factor information. As a result, erroneous detection of alcohol consumption detection can be suppressed and the accuracy of alcohol consumption detection can be improved.

An object of a system according to an embodiment is to provide appropriate advice for preventing excessive drinking based on a health condition and a physical constitution of a drinker.SOLUTION: A system includes a constitution acquisition part, a health condition collection part, a drinking data collection part, an advice provision part, and a physical condition check part. The physical constitution acquisition unit acquires a physical constitution of a drinker to alcohol. The health condition collection unit collects a health condition of today. The drinking data collection unit collects types and amounts of alcohol to be drunk. The advice providing unit gives advice when taking the next cup. The physical condition check unit checks a physical condition in cooperation with a watch device.SELECTED DRAWING: Figure 1

Previously, we were unable to support users in taking a break from alcohol. [Solution] A liver rest support device 1 can support a user in resting from alcohol by comprising: a performance receiving unit 123 that receives performance information which is information related to drinking history and is associated with date-specific information that identifies a day; a status acquisition unit 135 that acquires drinking status information which is information related to the difference or degree of agreement between the performance information and the target information for a predetermined period, by referring to a target management unit 115 that stores target information which identifies a goal for abstaining from alcohol during a predetermined period; an evaluation unit 136 that acquires evaluation information which identifies an evaluation of the liver rest using the drinking status information; and an evaluation output unit 143 that outputs the evaluation information.

The invention belongs to the crossing field of an automobile active safety system and a high-precision gas sensing technology, and provides a vehicle-mounted alcohol system and method which can avoid interference of other ethanol-containing substances and only detect gas exhaled by a driver. The system defects of an existing vehicle-mounted alcohol detection system in the aspects of reliability, anti-interference performance and integration are overcome. On the basis of traditional alcohol detection and photoacoustic spectrum detection, the detection sensitivity, reliability and accuracy are improved, meanwhile, the device can be integrally applied to a vehicle-mounted alcohol detection system, and the requirement for rapidly and accurately detecting whether a driver drinks alcohol or not in a vehicle in real time is met.

The invention provides application of hippophae rhamnoides extract in preparation of a product for dispelling the effects of alcohol or preventing and treating visceral organ injury caused by drinking, and belongs to the technical field of biological medicine. The invention provides application of a sea-buckthorn extract or a product containing the sea-buckthorn extract in preparation of a product for dispelling the effects of alcohol or preventing and treating visceral organ injury caused by drinking. The sea-buckthorn extract comprises sea-buckthorn fruit oil, sea-buckthorn seed oil and / or sea-buckthorn fruit pulp. The organ injury comprises alcoholic fatty liver, gastric mucosa injury or duodenum mucosa injury. The hippophae rhamnoides fruit extract (hippophae rhamnoides fruit pulp, hippophae rhamnoides fruit oil and hippophae rhamnoides fruit seed oil) and the hippophae rhamnoides fruit and Chinese wolfberry fruit composite primary pulp provided by the invention have the effects of promoting the repair of gastric mucosa and duodenal mucosa and further enhancing the immunity of gastrointestinal tracts, and can effectively prevent and / or treat gastritis, alcoholic fatty liver and duodenal mucosa injury caused by drinking; the traditional Chinese medicine composition can replace traditional medicine treatment and has the advantages of small side effect, economy, practicability, suitability for long-term administration and good compliance.

The invention discloses an intelligent detection method and system for drunk driving and fatigue states of a driver, and relates to the technical field of traffic safety detection.The detection method comprises the following steps that S10, the driver sits and ignites to start a vehicle, the alcohol concentration of the driver is collected through an alcohol collection sensor, the obtained alcohol concentration is compared with the threshold alcohol concentration, and the alcohol concentration of the driver is obtained; if the alcohol concentration exceeds the standard, a vehicle ignition circuit is forcibly disconnected; if the detected alcohol concentration does not reach the calibration value, the vehicle is normally ignited and started; s20, acquiring facial features and behavior state pictures of the driver by a camera, performing drinking state recognition and fatigue grade evaluation on the driver based on the facial features and the behavior states, and if the driver is judged to be in fatigue driving, prompting the driver in a voice prompt manner; and the facial features and the head posture of the driver are continuously and repeatedly detected until the driver is judged not to be in the fatigue driving state any more.

The utility model belongs to the technical field of alcohol blending appliances, and particularly relates to an appliance capable of blending different alcohol degrees, which comprises a measuring tool and a cover cap, the cover cap is sleeved on the periphery of the measuring tool in a sliding mode, the measuring tool is made of transparent plastic or glass, and a first vertical blending scale mark, a second vertical blending scale mark and a volume line are arranged on the peripheral surface of the measuring tool. The upper side of the measuring tool is integrally provided with a blocking ring used for clamping the cover cap. According to the utility model, through the cooperation of the first hooking and adjusting scale line and the second hooking and adjusting scale line on the measuring tool and the capacity line, the accurate degree-reduction hooking and adjusting operation can be realized. By means of the design, frequent alcoholic strength reducing operation of strong wine or original pulp wine is achieved, and the requirements for different alcoholic strength in the continuous drinking process can be met.

The invention discloses a traditional Chinese medicine compound preparation with the effects of protecting the liver, dispelling the effects of alcohol, invigorating the spleen and replenishing qi and a preparation method of the traditional Chinese medicine compound preparation. The preparation can quickly reduce the blood ethanol concentration of a patient suffering from alcoholic liver injury (28% of alcohol absorption can be reduced after drinking) and remarkably improve the liver cell membrane stability (GSH-Px activity is improved by 42%); meanwhile, the symptom of spleen and stomach qi deficiency is improved (the remission rate of anorexia is 89%). Through the dynamic temperature control decoction and vacuum concentration process, the retention rate of dihydromyricetin reaches 89%, which is increased by 53% compared with the traditional process. The traditional Chinese medicine composition is suitable for daily conditioning of people with alcohol abuse, drug-induced liver damage and sub-health, and is suggested to be taken within 30 minutes before and after drinking so as to enhance the protection effect.

The invention discloses a colorectal cancer related genetic molecular marker with an interaction effect with drinking and application of the colorectal cancer related genetic molecular marker. The genetic molecular marker is a combination of rs61355123, rs17624213, rs3791337, rs190489984 and rs2290476. According to the method, the limitation that a traditional genetic model only pays attention to the genetic main effect is broken through, and the multi-gene risk scoring model integrating environmental factors is constructed by recognizing a group of key SNP loci having remarkable interaction with drinking behaviors. The gene-environment collaborative assessment mechanism realizes more accurate risk stratification for drinkers. Clinical test data show that compared with a traditional genetic model, the genetic score of the integrated genetic marker provided by the invention has the following advantages: (1) the prediction accuracy is improved; (2) the clinical practical value is prominent; and (3) the intervention pertinence is enhanced.

The application discloses a kind of electric bicycle helmet alcohol detection systems based on hall sensor, to improve the safety of driver.The system includes helmet alcohol detection system and car speed control system, both are linked through wireless communication.Helmet alcohol detection system is built-in alcohol detection sensor module, human existence detection module and helmet interface detection module, for judging whether driver drinks and whether helmet is correctly worn.Car speed control system detects the voltage output by hall sensor in vehicle handlebar to judge vehicle driving state;when voltage is non-zero (vehicle driving), the system automatically queries the state of helmet alcohol detection system.If driver drinks or does not correctly wear helmet is detected, the system will make the vehicle unable to drive through car speed control system, and trigger sound and light alarm to remind driver.The application combines wireless communication and sensor technology, can effectively prevent drunk driving and not wearing helmet and other dangerous behaviors, significantly improve the safety of driver.

1. Name of the product in this design: Ceramic Wine Set (Discussing Heroes Over Wine). 2. Purpose of this design: For drinking alcohol. 3. The key design features of this product are the combination of shape and pattern. 4. Images or photos that best illustrate the design key points: usage status reference diagrams. 5. Other situations requiring explanation: The product is a package; Package 1 is a wine dispenser, and Package 2 is a wine glass.

Disclosed is a drinking system (1) witha drinking vessel (2) defining a receiving chamber (3) for a liquid,a drinking straw (4) arranged on the drinking vessel (2), projecting from the drinking vessel (2) and guided into the receiving chamber (3), with a first end having an inlet opening (5) which projects towards a base of the receiving chamber (3), and with a second end having a drinking opening (6), and with a suction channel (7) between the inlet opening (5) and the drinking opening (6), andan aroma reservoir (8) connected with the drinking straw (4) via an inflow channel (9).According to the invention, the drinking system is characterized in that the aroma reservoir (8) contains a liquid aroma medium which contains fragrances and / or flavorings in dissolved or emulsified and thus diluted form and which, when liquid is sucked from the drinking vessel (2) through the drinking straw (4), is sucked through the inflow channel (9) into the drinking straw (4) and is mixed there with the liquid sucked into the drinking straw (4) from the drinking vessel (3).