42 results about "Araneosene" patented technology

The invention is applicable to the technical field of metal organic framework materials, and provides a pillararene-based metal organic framework material and a preparation method thereof.The pillararene-based metal organic framework material takes a compound PY2-P5 as a ligand, and the material is one of PMOF1, PMOF2 and PMOF3; the PMOF1 is of a Cu4I4 cubic tetramer structure; the PMOF2 is of a Cu4I4 ladder tetramer structure, and the Cu4I4 ladder tetramer structure is a And the PMOF3 has a CuI one-dimensional chain structure. By introducing the pillararene ligand and regulating and controlling the coordination mode of the pillararene ligand and cuprous iodide, the metal organic framework material with stable structure and functional characteristics is constructed, the metal organic framework material has the dual advantages of host recognition site and fluorescence signal response, and can selectively distinguish 1-bromoalkane and 2-bromoalkane; a remarkable fluorescent blue shift signal is shown in the adsorption process, so that the visualization of molecular recognition and sensing is realized; the excellent molecular recognition capability of pillararene is maintained, the stability and reusability of the material are improved through framing, and a new way is provided for selective detection and separation of volatile organic compounds.

The invention belongs to the field of organic photoelectric materials, and relates to a cyanoindanone-modified boron-aza polycyclic aromatic hydrocarbon, and a preparation method and application thereof, and the cyanoindanone-modified boron-aza polycyclic aromatic hydrocarbon has a structure as shown in a general formula I and a general formula II. The cyanoindanone-modified boron-nitrogen heterocyclic polycyclic aromatic hydrocarbon provided by the invention shows the properties of wide spectrum and strong absorption, and meanwhile, the boron-nitrogen compound has a red-shifted absorption edge which can reach 815 nm at most.

This invention discloses a method for synthesizing 3-oxa[3.1.1]spiropropane, belonging to the fields of organic synthetic chemistry and medicinal chemistry. This method is the first to introduce oxygen atoms into the high-strength skeleton of [3.1.1]spiropropane, successfully synthesizing the 3-oxa[3.1.1]spiropropane molecule. The specific synthetic route is as follows: starting with 3,3-bis(bromomethyl)oxacyclobutane, the 3-oxabicyclo[3.1.1]heptane diol skeleton is constructed sequentially via nucleophilic substitution with diethyl malonate, reduction, and intramolecular cyclization. Then, oxidation and Barton decarboxylation iodination are performed to obtain the key intermediate 1,3-diiodo-3-oxabicyclo[3.1.1]heptane, which is finally reacted with an organolithium reagent to obtain the target product. This invention fills a technological gap in the synthesis of heteroatom-substituted spiroalkyl, providing a key precursor for the subsequent development of its free radical bifunctionalization reaction and the construction of structurally diverse 3-oxabicyclic [3.1.1]heptane dominant skeletons. It has important application prospects in drug design, especially as a bio-electroisoster of meta-substituted aromatics.

The invention relates to a compound of formula (I) and to the process for the preparation thereof (I) in which: - T is selected from the group consisting of CN+-O-, CH=NOH and CHO; - A represents a C6-C14 arenediyl ring, optionally substituted by one or more hydrocarbon chains, identical or different, aliphatic, preferably saturated, linear or branched; - E represents a C2-C12 divalent hydrocarbon group optionally comprising one or more heteroatoms; and - Ra, Rb, Rc, identical or different, represent a C1-C6 alkyl.

A catalyst for converting C9+ aromatics to lighter aromatics comprises metal functional groups derived from a metal such as platinum confined in cages and / or channels of a microporous material such as chabazite, wherein the cages and / or channels of the microporous material comprise metal functional groups defined by 8 or fewer tetrahedral atoms and acidic functional groups derived from an additional zeolite having cages and / or channels defined by 10 or more tetrahedral atoms, wherein the microporous material providing the metal functional groups and the additional zeolite providing the acidic functional groups are bound together by a binder.

To provide guest phosphorescent materials for use in organic electroluminescent components useful in enhancing the photochemical stability, preventing undesirable host and guest interactions, extending the lifetime of the components, achieving high color purity, and the like.SOLUTION: The disclosure provides: metal platinum (II) complexes having a [2.2]paracyclophane-based structure shown in Formula (I); and electronic components and apparatuses that employ the complexes.SELECTED DRAWING: Figure 1

The invention discloses a calixarene derivative and a preparation method and application thereof, the structure of the calixarene derivative is as shown in formula I: R1 is CO2-NH4 < + >; r2 is any one of straight-chain alkyl, branched-chain alkyl, straight-chain alkyl containing double bonds and branched-chain alkyl containing double bonds. According to the invention, iodobalix [4] arene and an alkynyl-containing phenyl compound are connected through a Sonogashira coupling reaction to construct an extended aromatic macrocyclic skeleton, and then an ionic water-soluble structure is obtained through upper edge ester group hydrolysis. The calixarene derivative has the following innovative advantages that the depth and the volume of a cavity are remarkably increased, and large-volume guest molecules can be efficiently included; the extended cavity realizes effective inclusion of guest molecules through hydrophobic interaction and Van der Waals force; an upper edge carboxylate radical ion group specifically recognizes a cationic object through electrostatic interaction, so that the multi-site recognition function of enzyme is simulated; the water solubility is enhanced, and the method is suitable for the biological medicine fields of drug delivery, ion sensing and the like.

The invention discloses a torsion regulation-based ultrafast broadband optical limiting material design method, a material and application, and relates to the field of optical limiting materials.The torsion regulation-based ultrafast broadband optical limiting material design method comprises the steps that structure optimization is conducted on double-branched-chain polycyclic aromatic hydrocarbon molecules through a computer based on the density functional theory, then the vibration frequency of each molecule is calculated, and the vibration frequency of each molecule is calculated; ensuring that the molecular configuration of the double-branched-chain type polycyclic aromatic hydrocarbon molecule after structure optimization is at the lowest point of a potential energy surface, and obtaining the double-branched-chain type molecule with a polycyclic conjugated structure, wherein the dihedral angle between a core group and a side chain group is 90 degrees; and adjusting a pi bridge between the core group with the polycyclic conjugated structure and the side chain group, so that a dihedral angle between the core group and the side chain group is gradually changed from 90 degrees to 0 degree, thereby obtaining the ultrafast broadband optical limiting material. The research of the invention clearly clarifies the anti-saturated absorption enhancement mechanism of the two-branch anthracene derivatives, and lays a foundation for the development of novel organic optical limiting materials.

This invention provides a column[5]arene-based bicyclic molecule that can detect dichromate ions with high selectivity and high sensitivity through enrichment effect. The column[5]arene-based bicyclic chemical sensor BPN1 was obtained by reacting bis-N-(2-aminoethyl)-2-(hexamyl)acetamide-functionalized column[5]arene with 1,4,5,8-naphthalenetetracarboxylic anhydride in DMF solution. The DMSO-H2O solution of the bicyclic chemical sensor BPN1 showed fluorescence at 455 nm, and the addition of Cr2O7... 2‑ The addition of other ions to the aqueous solution of BPN1 can induce fluorescence quenching, while the fluorescence of BPN1 does not change significantly upon the addition of other ions. Therefore, the dual macrocyclic chemical sensor BPN1 enables the detection of Cr2O7. 2‑ Single-selective recognition. Fluorescent titration experiments showed that this sensor molecularly recognizes Cr2O7. 2‑ It has high sensitivity.

The present invention relates to the technical field of biomedicine, and in particular to a preparation method for 18F-DOPA and an F-18-labeled precursor thereof. The structural formula of an F-18-labeled phenolic precursor compound is as shown in formula I, wherein R1 and R2 are hydroxyl protecting groups; R3 is a leaving group; R4 and R5 are each independently hydrogen or an amino protecting group; and R6 is a carboxyl protecting group. The present invention provides a simple and efficient preparation method for 18F-DOPA, specifically by constructing a key phenolic precursor compound and by means of a simple and efficient photocatalytic aromatic hydrocarbon deoxyfluorination reaction to implement the preparation of 18F-DOPA. The method has fewer steps, high yield, simple and convenient operation, good reproducibility, and good automated production potential. The radiotracer 18F-DOPA synthesized by means of the method has high specific activity and high chemical purity and radiochemical purity, and has significant value for the clinical promotion of 18F-DOPA.

A process for fluorination of a fluoride acceptor species comprising contacting an organofluorine species with a base to provide a fluoride donor species and contacting the fluoride donor species with the fluoride acceptor species to form a fluorinated species. The organofluorine species can be a species of formula (1): R1R2HC-CFR3R4; (1a): R1R2C=CFR3, or a fluoroarene; wherein R1, R2, R3 and R4 are each independently selected from H, halogen, and substituted or unsubstituted alkyl, alkoxide, aminoalkyl, or aryl.

The application relates to the technical field of organic functional molecule synthesis, and particularly discloses a pyran unit embedded bisanthene compound and a synthesis method. The method takes compound 1 as raw material, and under the condition of a sodium borohydride and boron trifluoride ether collaborative reduction system and room temperature, a single selective edge pyran ring is constructed through carbonyl activation-hydrogen transfer-intramolecular cyclization, and the yield is 60%, and the atomic economy is high. The obtained compound A has a maximum absorption characteristic peak at 726 nm in dichloromethane, and a maximum emission characteristic peak at 960 nm; after being made into nanoparticles, the photo-thermal conversion efficiency reaches 53% under the irradiation of an 808 nm laser (0.5 W cm-2), and the photo-thermal stability is significantly improved. The synthesis route has the advantages of mild conditions, simple operation and high atomic economy, and provides a universal strategy for the functionalization of oxygen-doped fused ring arenes and the preparation of high-efficiency photo-thermal materials.

Stilbene derivatives, a preparation method therefor and the use thereof are provided. Compounds of formula (I-1), and stereoisomers, pharmaceutically acceptable salts or prodrugs thereof can serve as an aryl hydrocarbon receptor (AHR) regulator. Compared with marketed drug Benvitimod, the compounds of formula I-1 have greatly improved molecular structure stability under illumination, thus overcoming photoinstability of Benvitimod, and solving the problem of Benvitimod being liable to degrade under illumination. In addition, the compounds of formula I-1 have remarkably improved activity on AHR protein. And finally, the preparation method for the compounds of formula I-1 is simple, and can achieve gram-level or kilogram-level preparation.

The invention relates to a compound of the formula (i); Py-X (i) wherein: Py is a polycyclic aromatic hydrocarbon moiety, X is a therapeutic moiety or a diagnostic moiety or a bioactive moiety, and wherein the therapeutic moiety or the diagnostic moiety or a bioactive moiety is not an osmium complex.

This invention designs and synthesizes a compound based on 1,10-phenanthroline and 4-(9-carbazolyl)phenylboronic acid, which is obtained in one step via the Suzuki-Miyaura reaction. This method has the advantages of mild reaction conditions, simple reaction steps, and high product yield. Due to the intermolecular C-H…π interactions, the compound forms a three-dimensional network structure with cavities in the crystalline state. This gives the small molecule compound the same excellent properties as traditional macrocyclic aromatic hydrocarbons, allowing it to self-assemble into non-covalent molecular channels for adsorbing and encapsulating benzene-based pollutants without any induction. The adsorption process of this invention has low energy consumption, short adsorption time, low equipment requirements, and the selected crystalline material is easy to synthesize, resulting in high yield, strong stability, high adsorption capacity for benzene-based pollutants, and good adsorption effect.

The application discloses a method for preparing a deuterated compound through a boron-type reduction reaction under a transition metal-free condition and the deuterated compound obtained through the method. The method comprises the following steps: under the protection of an inert atmosphere and under normal temperature and pressure, de-aromatic deuterization is performed on (hetero)arene through an electro-optical catalysis method in the presence of a deuterated reagent, so that the deuterated compound is obtained. The method directly reduces an organic photocatalyst which is independent of a transition metal into a corresponding anion radical through an electro-optical catalysis synthesis technology, and the anion radical has strong reduction capacity after being excited by light, so that boron-type reduction deuterization of inert (hetero)arene is realized. The method is more moderate, has fewer side reactions, and has high yield of a target product.

The application belongs to the field of supramolecular chiral calixarene, and particularly relates to a preparation method of chiral camphor sulfonamide modified oxacalix[4]arene, which comprises the following steps: step one, preparation of chiral camphor sulfonamide modified oxacalix[4]arene; and step two, host-guest property research of chiral camphor sulfonamide modified oxacalix[4]arene. The application first prepares tetranitro oxacalix[4]arene through an aromatic nucleophilic substitution reaction, reduces nitro groups into amino groups, introduces camphor sulfonyl chloride derivative modules, and realizes preparation of chiral tetra-camphor sulfonamide derived oxacalix[4]arene through acylation reaction. The introduction of camphor sulfonamide enables it to simultaneously act as a hydrogen bond donor and a hydrogen bond acceptor, forms hydrogen bonds with guest molecules respectively, and occurs intermolecular interaction, and the synergistic effect of multiple sulfonamide groups can further expand and enhance the interaction force between the oxacalix[4]arene host and the guest molecules.

A catalytically active salt including at least one boron cluster dianion and at least one cation. The cation includes a silylium cation having at least one silicon-bonded halogen atom. A composition including the catalytically active salt and at least one halosilane compound is also disclosed. A use of the catalytically active salt to couple an arene compound to a silicon atom of a hydridosilane compound is further disclosed. A use of the catalytically active salt to facilitate the exchange of one silicon-bonded alkyl group of a first silane molecule with a silicon-bonded halogen atom of a second silane molecule is also disclosed.

The present invention relates to a process for treating a mixture containing polyalkylaromatic hydrocarbons for the purpose of a transalkylation process, which comprises a mild reduction with hydrogen in the presence of a suitable hydrogenation catalyst. The present invention also relates to a process for the transalkylation of polyalkylaromatic hydrocarbons comprising said treatment.

The invention relates to a compound of formula (I) and its preparation process [Chem 47] (I) in which: T is chosen from the group consisting of CN+-O-, CH=NOH and CHO; A represents a C6-C14 arenediyl ring, optionally substituted by one or more identical or different, aliphatic hydrocarbon chains, preferably saturated, linear or branched; E represents a C2-C12 hydrocarbon divalent group optionally comprising one or more heteroatoms; and Ra, Rb, Rc, identical or different, represent a C1-C6 alkyl.

To provide a fluorene compound exhibiting high heat resistance, and to provide a method for producing the same and use thereof.SOLUTION: A compound represented by formula (1) is prepared. (In the formula, R1 represents a substitution group, m1 represents an integer of 0 to 8, Z1a and Z1b independently represent an arene ring, A1a and A1b independently represent an alkylene group, n1a and n1b independently represent an integer of 0 or more, R2a and independently represent a saturated aliphatic group, and independently represent a substitution group, and and independently represent an integer of 0 or more.) R2b m3b R3a m3a R3b. ) SELECTED DRAWING: None