Disclosed high-strength self-compaction thermal-insulation concrete is prepared by taking a self-compaction concrete technology as a basis, taking sea-mud-texturized high-performance spherical high-strength ceramic particle as an aggregate and scientifically mixing with cement, fly ash, graded sand, water, an efficient water reducer and cellulose ether. The obtained high-strength self-compaction thermal-insulation concrete has the dry apparent density of 1200-2000 Kg/m<3>, the 28-day compressive strength of 15-60 MPa, the heat conduction coefficient of 0.15-0.5 W/(m*K), the slump flow of 650-750 mm, the slump flow time of 3-4 s and the slump of 250 mm or more, also has light weight, high strength, high thermal-insulation performance and self-compaction performance during pouring, is capable of solving the problems that lightweight aggregates float upwards, are separated when being pumped and the like during pouring vibration of conventional high-strength thermal-insulation concrete, and is widely applied to bearing and non-bearing walls, floorslabs, roof boards, wallboards and other in-situ casted and prefabricated parts in energy-saving buildings.