17 results about "Sorbitan monolaurate" patented technology

The present invention relates to ophthalmic compositions comprising troxerutin and a surfactant selected from the group consisting of polyoxyl 35 castor oil, polyoxyl 40 hydrogenated castor oil, polyoxyethylene (20) sorbitan monooleate, polyoxyethylene (20) sorbitan monolaurate, and mixtures thereof, wherein the weight ratio of troxerutin to the surfactant is from 0.02:1 to 100:1, wherein the surfactant is present in an amount of up to 7 wt% with respect to the total weight of the composition, and wherein the composition is in the form of a solution, a suspension or a gel. The invention also relates to said composition for use in the treatment of dry eye disease.

Pharmaceutical aerosol formulations containing pre-micronized albuterol sulfate, high amount of green propellant trans-1,3,3,3-tetrafluoropropene (HFO-1234ze(E)), and a surfactant (polysorbate 80 (polyoxyethylene (20) sorbitan monooleate), polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate), polyethylene glycol 1000, span 85 (sorbitan trioleate), polyvinylpyrrolidone K25, or their combination) in a pressurized metered dose inhaler are described. The formulations do not use any co-solvent, i.e., they are co-solvent-free (e.g., free of ethanol, glycerol, propylene glycol, and a combination thereof). The formulations provide highly efficient delivery, through metered dose inhaler (MDI), of pre-micronized albuterol particles into the patients' respiratory tracts and have the advantages of high efficacy, improved safety, and a low global warming potential (GWP) for environmental impact.

The application relates to the technical field of cosmetics, in particular to a water-in-oil system makeup primer and a preparation method thereof. The water-in-oil system makeup primer comprises the following components in parts by weight: cosmetic-grade purified water, cetyl PEG / PPG-10 / 1 dimethicone, dimethicone, isononyl isononanoate, synthetic wax, microcrystalline wax, glycerol, 1,3-propanediol / octyldodecanol / ethylhexylglycerin, butylene glycol, sodium chloride and a polyoxyethylene (20) sorbitan monolaurate-polyoxypropylene (4) sorbitan monolaurate compound. The water-in-oil system makeup primer provided by the application can realize 80% high-aqueous-phase stable bearing, provide sufficient moisturizing reserves for dry skin, realize instant film forming and water locking during smearing, improve the water retention rate to more than 85%, solve the problem of water supplement efficacy attenuation, thereby realize the dual effects of instant water locking and long-acting moisturizing, and resolve the contradiction between water locking and skin feeling.

The present invention discloses a novel stable, single phase aqueous suspension for nasal administration to treat bacterial sinusitis. The composition takes azithromycin dihydrate as an active ingredient, and adopts a suspending agent system to prevent phase separation during storage. Embodiments include a formulation comprising a sorbitan monolaurate, or a combination of chitosan and a sorbitan monolaurate, to maintain the stability of the suspension. The present invention has a variety of advantages, including local delivery of azithromycin to an infected site, which can reduce systemic exposure and associated side effects compared to oral formulations.

The invention belongs to the technical field of biological medicine, and particularly discloses a sprayable double-network hydrogel microsphere adhesive and a preparation method and application thereof.The preparation method comprises the following steps that liquid paraffin, sorbitan monooleate and polyoxyethylene sorbitan monolaurate serve as oil phases, and an emulsion is formed; fully mixing the emulsion with petroleum ether, centrifugally separating gel microspheres, freeze-drying, and storing in a dark place; preparing a ropivacaine liposome; and adding ultrapure water into the lipid membrane to obtain a primary liposome suspension, adsorbing the liposome by using the hydrogel microspheres, and collecting the obtained dual-network hydrogel microspheres. According to the sprayable double-network hydrogel microsphere adhesive as well as the preparation method and the application thereof, prepared hydrogel microspheres can quickly and consistently cover irregular wounds, and liposome loaded with ropivacaine provides continuous analgesic release, so that the painful wound healing effect is improved. By simultaneously solving the problems of maintaining continuous adhesion and prolonging pain relief in blood-saturated wounds.

This invention relates to ophthalmic compositions comprising troxerutin and a surfactant selected from polyoxyethylene 35 castor oil, polyoxyethylene 40 hydrogenated castor oil, polyoxyethylene (20) sorbitan monooleate, polyoxyethylene (20) sorbitan monolaurate, and mixtures thereof, wherein the weight ratio of troxerutin to the surfactant is from 0.02:1 to 100:1, wherein the surfactant is present in an amount of up to 7% by weight relative to the total weight of the composition, and wherein the composition is in the form of a solution, suspension, or gel. The invention also relates to the compositions for treating dry eye disease.

An example of the present invention provides a fuel additive composition, which includes a mixture of a mixture of tert-butylhydroquinone, a catalyst, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, and a lubricant. The CAS number is 1948-33-0), and the CAS number is 1948-33-0), and the CAS number is 1948-33-0), and the CAS number is 1948-33-0, and the CAS number is 1948-33-0; the invention relates to a calcium acetylacetonate hydrate and a preparation method thereof. The calcium acetylacetonate hydrate is characterized in that the CAS number is 61789-86-4. The invention relates to a high-base-number petroleum calcium sulfonate, which is characterized in that the CAS number is 345909-31-1), and the high-base-number petroleum calcium sulfonate is prepared by the following steps of: preparing a high-base-number petroleum calcium sulfonate, a high-base-number petroleum calcium sulfonate and a high-base-number petroleum calcium sulfonate; the CAS number is 68783-96-0), and the content of sorbitan monolaurate (Sorbitan monolaurate; the CAS serial number is 1338-39-2) and 2-ethylhexyl nitrate ester (2-ethylhexyl nitrate; the CAS serial number is 1338-39-2) and 2-ethylhexyl nitrate ester (2-ethylhexyl nitrate; and the CAS serial number is 27247-96-7). The fuel additive composition according to one embodiment of the present invention can be added to various fuels such as gasoline, light oil, heavy oil and the like to improve the combustion efficiency at the time of fuel combustion while significantly reducing the generation of atmospheric pollutants such as particulate matter (PM), carbon monoxide (CO), hydrocarbon (HC), nitrogen oxide (NOx) and the like.

To propose a method for effectively reducing the amount of fluorine-containing emulsifiers that may remain in aqueous emulsion polymerization solutions of fluoropolymers, including fluoroelastomers and perfluoroelastomers. [Solution] The following steps: A process of passing a weakly acidic aqueous solution through a hydroxide ion type strongly basic anion exchange resin. A step of adding polyoxyethylene (20) sorbitan monolaurate to an aqueous dispersion of fluoropolymer containing a fluorine-containing emulsifier, followed by A step to obtain an aqueous fluoropolymer dispersion by passing a fluoropolymer aqueous dispersion containing polyoxyethylene (20) sorbitan monolaurate and a fluorine-containing emulsifier through a strongly basic anion exchange resin through which the weakly acidic aqueous solution has been passed. A method for producing an aqueous dispersion of a fluoropolymer containing at least [a specific substance] is provided. Furthermore, a method for producing a fluoropolymer is provided for obtaining a fluoropolymer from the obtained aqueous dispersion of a fluoropolymer.

This invention relates to a wall painting coating and its preparation method, belonging to the field of polymer coating technology. The wall painting coating of this invention comprises the following components in parts by weight: 35-45 parts of waterborne acrylic copolymer emulsion; 15-25 parts of waterborne iron oxide red paste; 1.8-2.5 parts of silane-modified attapulgite clay; 0.4-0.6 parts of associative polyurethane thickener; 0.6-1.0 parts of wood fiber; 0.8-1.2 parts of wetting and dispersing agent; 0.15-0.2 parts of defoamer; 2.0-3.0 parts of film-forming aid; and 31-33 parts of water. The wetting and dispersing agent is sorbitan monolaurate, N,N-bis(2-hydroxypropyl)-dodecanoamide, or N-tris(hydroxymethyl)methyl-citrate monohydrazide amide.

Provided is an emulsifier composition containing: (A) a polyoxyalkylene alkyl ether represented by formula (1); (B) one or more sorbitan mono-fatty acid esters selected from the group consisting of sorbitan monolaurate, sorbitan monomyristate, sorbitan monopalmitate, sorbitan monostearate, and sorbitan monooleate; and (C) one or more polyhydric alcohols selected from the group consisting of 1,2-alkanediols having 6-18 carbon atoms and monoalkyl glyceryl ethers having a hydrocarbon group having 6-8 carbon atoms. In formula (1), R1 represents an alkyl group having 10-18 carbon atoms, and the average values of n and m independently represent a number of 0-10. Provided that, at least one of n and m is not 0.

The invention discloses an emulsifier, a preparation method and an application method, the emulsifier has the advantages of low cost, environmental protection, food safety and easiness in use, and the problems of high consumption, high cost and potential food safety of traditional milk in coffee art practice are solved. The emulsifier is prepared by mixing polyoxyethylene (20) sorbitan monolaurate and polyethylene glycol 400 monooleate according to a specific mass ratio, and can simulate the physical characteristics, including density, stability and milk foam quality, of the whipped milk at normal temperature. Through an accurate formula and a simple preparation process, the emulsifier disclosed by the invention can provide experience similar to that of real milk in the coffee art, meanwhile, the dependence on milk is reduced, the food waste is reduced, and the practice efficiency of coffee professionals is improved. Besides, the main component of the emulsifier is a food additive, so that the emulsifier is safer to use and does not threaten human health, and the environmental problem possibly caused by using chemical raw materials is also avoided.

Pharmaceutical aerosol formulations containing pre-micronized albuterol sulfate, high amount of green propellant trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), and a surfactant (polysorbate 80 (polyoxyethylene (20) sorbitan monooleate), polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate), polyethylene glycol 1000, span 85 (sorbitan trioleate), polyvinylpyrrolidone K25, or their combination) in a pressurized metered dose inhaler are described. The formulations do not use any co-solvent, i.e., they are co-solvent-free (e.g., free of ethanol, glycerol, propylene glycol, and a combination thereof). The formulations provide highly efficient delivery, through metered dose inhaler (MDI), of pre-micronized albuterol particles into the patients' respiratory tracts and have the advantages of high efficacy, improved safety, and a low global warming potential (GWP) for environmental impact.

The subject of the present invention is an adjuvant composition, in particular for activating agrochemicals, comprising water, ammonium sulfate, hydroxypropyl guar gum, at least one surfactant, a silicone defoamer, characterized in that the adjuvant composition contains oleyl alcohol, and at least one surfactant, and the surfactant is selected from the group consisting of at least one alkoxylated fatty alcohol, an alkyl polyglycoside, a polyethoxylated sorbitan monolaurate, and combinations thereof, and the ratio of water: ammonium sulfate: hydroxypropyl guar gum: surfactant: silicone defoamer: oleyl alcohol expressed in wt. Relative to the total adjuvant composition is 35 wt.% to 47 wt.%: 25 wt.% to 34 wt.%: 1.5 wt.% to 2 wt.%: 17 wt.% to 22 wt.%: 0.03 wt.% to 0.07 wt.%: 4.5 wt.% to 5.5 wt.%, respectively. The subject of the invention is also a process for preparing an adjuvant composition, characterized in that it comprises the following phases: phase I. mixing water, ammonium sulfate and at least one surfactant in a ratio of 35 wt.% to 47 wt.%: 25 wt.% to 34 wt.%: 17 wt.% to 22 wt.%, respectively, to obtain a mixture A; stage II. Mixing oleyl alcohol, a silicone defoamer and hydroxypropyl guar gum in a ratio of 4.5 wt.% to 5.5 wt.%: 0.03 wt.% to 0.07 wt.%: 1.5 wt.% to 2 wt.%, respectively, to form a mixture B; stage III, adding the mixture B to the mixture A while continuously mixing the mixture A, and continuing mixing after combining the mixture A and the composition B; wherein the proportions of these components are expressed in% by weight in the final mixture of stage III and the surfactant in stage I is selected from the group consisting of at least one alkoxylated fatty alcohol, an alkyl polyglycoside, a polyethoxylated sorbitan monolaurate, and combinations thereof. Another subject of the invention is the use of an adjuvant composition according to any of claims 1 to 8 for the preparation of a mixture having an agrochemically active substance, the mixture being selected from the group consisting of stable, ready-to-use mixtures incorporated into formulations of the agrochemically active substance (s), and mixtures of the agrochemically active substance (s), or mixtures of the agrochemically active substance (s), or mixtures of the agrochemically active substance (s), or mixtures of the agrochemically active substance (s), or mixtures of the agrochemically active substance (s), or mixtures of the agrochemically active substance (s), or mixtures of the agrochemically active substance (s). And a mixture added immediately prior to spraying to the atomizer tank in which (e) agrochemically active substance is located.

The invention relates to the technical field of cosmetics, in particular to water-in-oil system pre-makeup cream and a preparation method thereof. The water-in-oil system pre-makeup cream comprises the following components in parts by weight: cosmetic-grade purified water; and cetyl PEG (Polyethylene Glycol) / PPG-10 / 1 polydimethylsiloxane. A polydimethylsiloxane; isononyl isononanoate; synthetic wax; microcrystalline wax; glycerol; 1, 3-propylene glycol / caprylyl glycol / ethylhexylglycerin; butanediol; sodium chloride; and a compound of polyoxyethylene (20) sorbitan monolaurate and polyoxypropylene (4) sorbitan monolaurate is prepared from the polyoxyethylene (20) sorbitan monolaurate and the polyoxypropylene (4). The water-in-oil system pre-makeup cream provided by the invention can realize 80% high water phase stable bearing, and provides sufficient moisturizing reserve for dry skin; meanwhile, in the smearing process, instant film forming and water locking can be achieved, the water retention rate is increased to 85% or above, and the problem that the water supplementing effect is attenuated is solved, so that the double effects of instant water locking and long-acting moisturizing are achieved, and the contradiction between water locking and skin feeling is eliminated.

The present application relates to frozen food, in particular to a freeze-resistant chocolate and a preparation method thereof. The freeze-resistant chocolate coating contains a stabilizer composition composed of sorbitan monolaurate, sucrose fatty acid ester and polyglycerol fatty acid ester in a weight ratio of (1-4):(1.5-5):(5-10). The present application can improve fat crystals and more effectively prevent problems such as ice cream chocolate frost, brittle skin cracking, and dregs dropping by adding a stabilizer composition composed of sorbitan monolaurate, sucrose fatty acid ester and polyglycerol fatty acid ester in a specific ratio to the chocolate.

A biological agrochemical composition and method of synthesis thereof, are disclosed. Said biological agrochemical composition broadly comprises: a filtrate of Lactobacillus acidophilus; a filtrate of Aspergillus niger; neem oil; and polyoxyethylene (20) sorbitan monolaurate. The disclosed biological agrochemical composition offers at least the following synergistic advantages and effects: is efficient; is non-toxic; is environment- friendly; improves soil fertility; and / or is effective against a broad range of weeds.