The invention discloses a radiation-resistant flame-retardant cable insulation material. The radiation-resistant flame-retardant cable insulation material is prepared from, by weight, 80-90 parts of ethylene propylene diene monomer, 30-40 parts of chloroprene rubber, 40-50 parts of ABS resin, 20-30 parts of ethylene-tetrafluoroethylene copolymers, 10-20 parts of barium sulfate, 10-15 parts of lead oxide, 20-25 parts of rare earth oxide, 10-20 parts of silicon nitride, 15-25 parts of hard clay, 20-30 parts of nanometer hydrogen peroxide, 1-1.5 parts of an aluminum zirconium coupling agent TL-5, 4-8 parts of 1,1,3,3-tetramethylbutyl hydroperoxide, 0.5-1.1 parts of sulfur powder, 0.8-1.2 parts of an assistant cross-linking agent TAIC, 0.4-0.8 part of an assistant cross-linking agent HVA-2, 2-4 parts of melamine cyanurate, 4-6 parts of magnesium oxide, 2-5 parts of triphenyl phosphate, 3-6 parts of zinc stearate and 3-4 parts of an anti-aging agent. The radiation-resistant flame-retardant cable insulation material is excellent in radiation resistance, good in mechanical performance, flame-retardant resistance and tensile and wear resistance, long in service life and suitable for high-radiation fields, and particularly, is suitable for nuclear power stations.