2results about How to "Efficient dismantling" patented technology

The present application relates to the field of pharmaceutical preparation and nanomedicine, and particularly relates to a kind of nano-drug composition, its combined drug delivery system and application.The nano-drug composition comprises alpha 1-AR blocker and amphiphilic nano-carrier;The alpha 1-AR blocker is loaded in the hydrophobic core formed by amphiphilic nano-carrier;The alpha 1-AR blocker is selected from one or more of prazosin, terazosin, doxazosin;The average particle size of the nano-drug composition is 220-260 nm, the polydispersity index is less than 0.3, and the encapsulation efficiency is greater than 50%.The nano-drug composition of the present application has dual functions of anti-tumor proliferation and immune microenvironment remodeling, improves the dispersion stability of the drug in physiological medium, effectively reduces the in vivo clearance rate, prolongs the circulation time, and realizes the efficient in vivo delivery of the drug.The preparation process of the nano-preparation is stable and can be produced on a large scale.

The present application relates to a kind of transformer core column automatic binding shaping device, it is related to transformer technical field.The automatic binding machine main body is installed with lifting column in the rear side of the automatic binding machine main body, lifting frame is connected with the sliding block position of lifting column, hollow turntable is installed in the bottom of lifting frame, bottom plate is connected with the bottom of hollow turntable, and winding disc is rotatably connected with the bottom of bottom plate.The present application, by starting motor drives screw rod to rotate, screw rod rotation drives sliding plate movement, sliding plate movement drives cutter plate and core column to be attached, and cutter plate will be vertically moved during the process of attachment to make rubber band enter to the cutting edge position of cutter plate and cut, it is convenient and fast, and lifting frame inside is equipped with identification inductor, and rubber band that surface has been coated with reaction material can be automatically surface, and then more efficiently gradually on the surface of core column winding rubber band can be disassembled, improve the binding efficiency of core column glass fiber band.