The invention provides a numerical control irregular glass cutting edging machining center device. The numerical control irregular glass cutting edging machining center device comprises an X shaft moving mechanism, a Y shaft moving mechanism, a Z shaft moving mechanism, an A shaft moving mechanism, a B moving mechanism, a C moving mechanism, a grinding head motor, a cutting grinding wheel, a suction disc and a tool changer. The X moving mechanism is located on the top portion of a main rack, the Y shaft moving mechanism is located on the lower portion of the X shaft moving mechanism, the Z shaft moving mechanism is located on the lower portion of the Y shaft moving mechanism, the C shaft moving mechanism is located on one side of the Z shaft moving mechanism, the A shaft moving mechanism and the B moving mechanism are respectively located on the lower portion of the C shaft moving mechanism, the grinding head motor is arranged on the A shaft moving mechanism, the cutting grinding wheel is arranged on the lower portion of the grinding head motor, the suction disc is located on a platform on the lower portion of a host machine, and the tool changer is located on the right lower portion of the host machine. The numerical control irregular glass cutting edging machining center device is capable of achieving plate glass cold machining, diversified cutting, and beveled edge and straight edge grinding of multi-arc and multi-angle combination.