The invention relates to the technical field of switch cabinets, in particular to a GCS low-voltage draw-out type switch cabinet with moisture-proof performance, which comprises a supporting structure, a sealing structure, a storage structure, an accommodating structure, a protection structure and a transmission structure, the arrangement of the sealing structure facilitates the sealing of the supporting structure, and the arrangement of the supporting structure facilitates the adjustment of the flatness of the accommodating structure in the same direction, thereby greatly improving the installation efficiency and quality of the accommodating structure. The protection structure can abut against the storage structure, the storage structure can be protected conveniently through the protection structure, misoperation of a rotary knob in the storage structure is effectively prevented, meanwhile, the storage structure is conveniently limited, and the stability of the storage structure is improved; and the transmission structure is conveniently driven through the protection structure, so that the transmission structure drives the storage structure to abut against the accommodating structure, the sealing performance between the storage structure and the accommodating structure is better, and the moisture-proof performance is greatly improved.