42 results about "Bacterial Conjunctivitis" patented technology

A method for treating ocular conditions such as bacterial keratitis, bacterial conjunctivitis, corneal ulcers and wounds, endophthalmitis, and blebitis in mammals, by using a native, synthetic, or recombinant CAP37, or effective peptide portions thereof including CAP37 peptides 20-44, 23-42, 102-122, and 120-146 and monocysteine derivatives of peptides 20-44 and 23-42. The CAP37, peptides, and peptide derivatives can also be used to store, clean, sterilize, or coat contact lenses, and may be used in media for storing mammalian corneal transplants.

A method for rapidly detecting infectious conjunctivitis in a host is provided. The method includes contacting an ocular test sample with a chromogen (e.g., Reichardt's dye) that exhibits a color change in the presence of a microbe. The present inventors have discovered that the extent of the color change may vary depending on whether the microbe is a bacteria or virus. Without intending to be limited by theory, the present inventors believe that the chromogen interacts with the peptidoglycan-based cell wall structure of bacteria to induce a color change that is even more apparent at infectious levels. It is believed that this interaction occurs to a much greater extent in bacteria than in viruses. Accordingly, although the chromogen may still undergo a color change in the presence of the viruses, it is typically to a much lesser extent. In this manner, the degree of color change of the chromogen may be used in the present invention as a mechanism for differentiating between viral and bacterial conjunctivitis.

The invention discloses azithromycin gel eye drops and a preparation process thereof. The eye drops are prepared from a main medicine, namely azithromycin and excipients such as an adhesive, a gel matrix, an isotonic regulator, a preservative, an antioxidant, a buffering agent and the like. The adhesive, namely polycarbophil in the eye drops can increase the biological adhesion of the eye drops, so that the detention time of medicines in eyes is further prolonged. The invention provides a practical, convenient and reliable ophthalmic preparation for treating bacterial conjunctivitis, and solves the problems that the detention time of medicines in an eye drop formulation in the eyes is short, the medicines are not easy to absorb, the bioavailability is low and the like.

The invention belongs to the technical field of medicine product processing, and in particular relates to dendrobe eye drops and a preparation method thereof. The dendrobe eye drops consist of the following components in percentage by mass: 40 to 65 percent of dendrobe, 10 to 23 percent of the root bark of the peony tree, 5 to 8 percent of rhizoma acori graminei, 2 to 10 percent of bighead atractylodes rhizome, 6 to 10 percent of fructus cnidii, 3 to 7 percent of biond magnolia flower, 2 to 5 percent of chitosan, 1 to 3 percent of vitamin B12 powder, 1 to 3 percent of vitamin B1 and 3 to 8 percent of normal saline. The dendrobe eye drops provided by the invention adopts the common traditional Chinese medicine components, is reasonable in compatibility and safe and reliable in medicine, has antibacterial and anti-inflammation effects, has remarkable treatment effect on eye diseases such as bacterial conjunctivitis and keratitis, and has the characteristics of exact curative effect, quick response, high curative ratio, no side effect and the like; and the preparation of the dendrobe eye drops is capable of storing effective components in the raw materials, reasonable in production process and suitable for industrialized production.

The present invention relates to a kind of Yizhihuang eye drops and its preparation method. It can be used for curing the diseases of conjunctivitis, bacterial conjunctivitis, viral conjunctivitis, acute hemorrhagic conjunctivitis, neonatal bacterial conjunctivitis and chronic conjunctivitis and keratitis, etc. It is made up by using four Chinese medicinal materials of lonicera flower, scutellaria root, capillaries and gardenia fruit through a certain preparation process.