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156 results about "Iterative design" patented technology

Iterative design is a design methodology based on a cyclic process of prototyping, testing, analyzing, and refining a product or process. Based on the results of testing the most recent iteration of a design, changes and refinements are made. This process is intended to ultimately improve the quality and functionality of a design. In iterative design, interaction with the designed system is used as a form of research for informing and evolving a project, as successive versions, or iterations of a design are implemented.

Iterative probe design and detailed expression profiling with flexible in-situ synthesis arrays

Methods and compositions are provided that are useful for detecting and reporting a plurality of different target polynucleotide sequences in a sample, such as polynucleotides corresponding to a plurality of different genes expressed by a cell or cells. In particular, the invention provides methods for screening a plurality of candidate polynucleotide probes to evaluate both the sensitivity and the specificity with which each candidate probe hybridizes to a target polynucleoide sequence. Candidate polynucleotide probes can then be ranked according to both their sensitivity and specificity, and probes that have optimal sensitivity and specificity for a target polynucleotide sequence can be selected. In one embodiment, polynucleotide probes can be selected according to the methods described herein to prepare “screening chips” wherein a large number of target polynucleotide sequences are detected using a single microarray have a few (e.g., 1–5) probes for each target polynucleotide sequence. In a particularly preferred embodiment, the invention provides a screening chip that can detect genetic transcripts from the entire genome of an organism. In an alternative embodiment, polynucleotide probes can be selected according to the methods described herein to prepare “signature chips” to more accurately detect certain selected “signature genes” using several polynucleotide probes (e.g., 10–20) for each signature gene. The invention additionally provides microarrays containing polynucleotide probes for a large number of genes expressed by a cell or organism. Further, methods for detecting a plurality of polynucleotide molecules, including a large number of genes expressed by a cell or organism, are also provided.
Owner:MERCK & CO INC

Sequence radial basis function agent model-based high-efficiency global optimization method

The invention relates to a sequence radial basis function agent model-based high-efficiency global optimization method, and belongs to the technical field of multidisciplinary optimization in engineering design. The method comprises the following steps of: according to initial conditions given by a user, selecting sample points in a primary iteration design space, calculating a response value of a true model, constructing a radial basis function agent model, calculating the current optimal solution of the radial basis function (RBF) agent model, calculating a response value of the possible optimal solution of the current iteration in the true model, judging whether the global optimization method meets the convergence criterion, determining an important sampling space of the next iteration, increasing new sample points in the constructed important sampling space by an experimental design calculation method, saving the new sample points in a design sample point database and making k equal to k+1, and switching to the constructed radial basis function agent model for the next iteration. Through the method, the true models in the engineering design and analysis software are approximated, and the optimization design of the true models only takes several or dozens of seconds, so the period of the engineering optimization design is greatly shortened, the design cost is greatly saved and the efficiency is obviously improved.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Reactor core iterative design system based on Monte Carlo calculation

The invention discloses a modeling system which is used in reactor design and used for reactor core component design. According to the modeling system, the geometric specificity of a fission reactor core is analyzed, a great amount of repeatedly constructed geometries are adopted, a CAD engineering model and a Monte Carlo calculation model of the fission reactor core are automatically established by establishing parameters, the Monte Carlo calculation model is used for radiating and transporting input of a Monte Carlo calculation program, and the significant physical quantity of the reactor core can be calculated after the Monte Carlo calculation model is obtained. By constantly evaluating the physical parameters of the calculation result, the modeling system can be used for performing repeated iteration correction on a design scheme of the fission reactor core till a reactor core scheme which makes a user satisfactory is made. The modeling system has the benefits that the tediousness that Monte Carlo calculation programs are written and files are input manually is avoided, the whole modeling process is very visible, the probability of mistakes is greatly reduced, and the design time of the reactor core is shortened.
Owner:HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI

Method for designing structure of low-cost test combustion chamber with reliable thermal protection

The invention discloses a method for designing a structure of a low-cost test combustion chamber with reliable thermal protection. The combustion chamber comprises a body barrel segment, a connecting flange, a nozzle part, a connecting bolt and a measuring filler neck part. The combustion chamber adopts a capacitive type structure; the body barrel segment is made of a pure copper material with a high thermal conductivity; and the nozzle part is made from a copper-infiltrated tungsten material. In the invention, a thermal analysis aided design method is required to be used firstly, which needs to establish a computation mode and a computing method at first and then perform an iterative design process of the structural design and the thermal analysis. The computation mode adopts an unsteady thermal-dimensional heat conducting differential equation and the computed heat exchange mainly comprises heat convection from the gas to the chamber wall and the radiant heat exchange, the heat conduction in the chamber wall, the convection from the chamber wall to the outside and the radiant heat exchange. The thermal analysis aided design method comprises a global computing analysis and a local correcting and computing analysis. The method can minimize the materials used under the condition that the combustion chamber has the reliable thermal protection and greatly reduce the cost.
Owner:BEIHANG UNIV

M-APSK (amplitude phase shift keying) signal to noise estimation method based on iterative decoding and decision feedback

The invention discloses an M-APSK (amplitude phase shift keying) signal to noise ration estimation method based on iterative decoding and decision feedback. The method includes subjecting a transport signal to utilize a variable bit rate decoder to obtain feedback result, modulating to obtain a receiving signal without noise, finding out relative position of the receiving signal on a constellation map, dividing into a plurality of circular rings, obtaining each circular ring receiving signal through solving rotation, calculating amplitude mean value of each circular ring receiving signal, calculating useful signal total power and transport signal total power according to the amplitude mean value, and calculating estimated value of signal to noise ratio. The concept of iterative estimation is adopted, iterative decoding output information bit is used for inverse modulation and constellation map division, and the data-aided algorithm is adopted to finish estimation of the signal to noise ratio, so that the problem of major errors in the constellation map division is solved, signal to noise estimation accuracy is improved, the problem of realizability and complexity brought by the maximum likelihood estimation method is avoided, and the M-APSK signal to noise ration estimation method based on iterative decoding and decision feedback has better application prospect.
Owner:NANJING 6902 TECH +1

Self-adaptive iterative decoding method for Turbo product codes

The invention provides a self-adaptive iterative decoding method for Turbo product codes. The self-adaptive iterative decoding method comprises the steps as follows: channel environment values obtained through simulation and simulation samples of corresponding iterative factors are stored in a storer; the channel environment values S are estimated according to soft information R output by a demodulation terminal; corresponding groups of most suitable iterative factors are selected according to different channel environment values S; then the soft information R and the selected iterative factors are sent into a Turbo code soft-input soft-output (SISO) iterative decoder to be decoded; a code word of the current time of decoding is detected by an iterative stopping judging unit and compared with a code word of the last time of decoding; and when the distance between the code word of the current time of decoding and the last time of decoding is smaller than or equal to an iterative threshold, the decoding is stopped and the code words are output, otherwise iterative decoding is continued. The self-adaptive iterative decoding method has the advantages that suitable iterative factors can be selected according to different channel environments to realize optimal decoding, the iterative times are selected in a self-adaptive manner, and power consumption of a receiver is effectively reduced.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV

Method for estimating size parameter of carrier rocket

The invention discloses a method for estimating the size parameter of a carrier rocket, belongs to the technical field of aerospace and aims to solve the technical problem of large calculation amountand inaccuracy during conventional size parameter selection. The method for estimating the size parameter comprises the following steps of: carrying out task index analysis, selecting an overall scheme and determining each system parameter; determining design variables, an optimization target and constraint conditions and building a corresponding mathematical model on the basis of a size parametermodel, wherein the size model comprises a part size calculating module, an engine size calculating module and an overall size calculating module for sequential calculation; carrying out size parametric modeling on the carrier rocket, writing an integrated calculation program and giving input and output files; selecting an optimization algorithm, inputting to an optimizer and selecting a size parametric model to obtain a reference design scheme. The method disclosed by the invention has the advantages that the iterative design times of the carrier rocket in the overall scheme stage is reduced;and the method is simple in process, small in calculation amount and high in efficiency.
Owner:BEIHANG UNIV
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