234 results about "Microbiological material" patented technology

A needleless valve assembly includes a needleless connector having a housing with an inlet end with an inlet opening and an outlet end with an outlet opening, and a valve disposed in the housing to control passage between the openings. The assembly also includes a collar having an exterior surface and an interior surface, and a first end with a collar opening communicating between the interior surface and the exterior surface and a second end moveably attached to the housing. Further, the assembly includes a barrier disposed across the collar opening with a slit therethrough and including an anti-microbial material. The collar is moveable relative to the housing so that the inlet end of the housing depends past the exterior surface of the collar through the slit in the barrier. A kit may include the assembly and a catheter having a first end attached to the outlet opening.

The present invention relates to an antimicrobial material comprising sheet of fabric and- metallic salt crystals embedded in an adhesive material covering the sheet of fabric.

A transcutaneous device dressing and method for its use with a transcutaneous medical device, such as an intravascular catheter, which punctures the skin of a patient and which has a portion of the medical device protruding from the skin which can lead to infection. The dressing includes a top and a bottom dressing, both being formed from a flexible material and having upper and lower surfaces, with the lower surface being the skin facing surface in use. The bottom dressing has a slit formed therein extending from one edge inwardly to a termination point within the confines of the bottom dressing. An anti-microbial material is provided without the use of adhesives at the upper and lower surfaces of the bottom dressing, and at least at the lower surface of the top dressing. In use, the bottom dressing is placed next to the skin, the slit allowing the bottom dressing to surround the puncture site such that the lower surface of the bottom dressing is in contact with the skin while the upper surface of the bottom dressing is in contact with a portion of the medical device protruding from the skin. The top dressing is placed above the puncture site such that its lower surface is in contact with a portion of the medical device protruding from the skin. In this way, there is exposure of the portion of the medical device protruding from the skin to the anti-microbial activity of the anti-microbial material.

An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from about 60 to about 95 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 0.25 wt % pigment, and about 0.5 to about 3.5 wt % lubricant. The silicone resin may be a dispersion of about 40 to about 60 w / v % of an RTV silicone resin in a solvent, a liquid silicone resin, or a solid silicone resin. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article and permitting the solvent to evaporate. It may also be formed by making a mixture of about 5 to about 12 wt % of an antimicrobial formulation and about 88 to about 95 wt % of a liquid or solid silicone resin and molding, overmolding, or extruding the article from the compounded mixture.

The present invention broadly comprises a multiport filter having at least three intake ports and at least two layers—a first layer for containing particles 3 microns or greater and a second layer that contains particles 3 microns or less in size. In alternate embodiments, the filter includes a third layer for trapping odors and gases and a fourth layer for trapping fines. The second layer may be comprised of ULPA material and may have antimicrobial material. The invention also includes a contaminant removal system for the filtering and recirculation of air contaminated with smoke from cautery-type surgical procedures. The invention also broadly comprises a surgical assemblies control service head designed to house powered surgical devices and a vacuum-filtering system for the treatment of air contamination caused by surgical procedures.

The invention is directed to efficient methods for depositing highly adherent anti-microbial materials onto a wide range of surfaces. A controlled cathodic arc process is described, which results in enhanced adhesion of silver oxide to polymers and other surfaces, such as surfaces of medical devices. Deposition of anti-microbial materials directly onto the substrates is possible in a cost-effective manner that maintains high anti-microbial activity over several weeks when the coated devices are employed in vivo.

A method is provided for depositing a hard wear resistant surface onto a porous or non-porous base material of a medical implant. The wear resistant surface of the medical implant device may be formed by a Laser Based Metal Deposition (LBMD) method such as Laser Engineered Net Shaping (LENS). The wear resistant surface may include a blend of multiple different biocompatible materials. Further, functionally graded layers of biocompatible materials may be used to form the wear resistant surface. Usage of a porous material for the base may promote bone ingrowth to allow the implant to fuse strongly with the bone of a host patient. The hard wear resistant surface provides device longevity, particularly when applied to bearing surfaces such as artificial joint bearing surfaces or a dental implant bearing surfaces. An antimicrobial material such as silver may be deposited in combination with a metal to form an antimicrobial surface deposit.

A luer adapter includes a body including an inner surface defining a lumen and first and second ends. Each end is adapted to connect to a medical device. An antimicrobial material is positioned at least on a portion of the inner surface. A barrier is positioned between the lumen and the antimicrobial material and permits the passage of the antimicrobial material therethrough upon exposure to moisture. The barrier may include hydrophilic material.

A treatment device having a first portion in a first plane, a treatment portion with a cover in a second plane that defines a treatment volume extending between the first and second planes, and a flexible transition portion that connects the first portion to the treatment portion. The treatment portion including a polymeric foam ring having interior and exterior walls extending from the first plane to the second plane. The cover spanning the interior wall thereby forming a closed treatment volume. The polymeric foam ring may be impregnated with a medicament selected from the group including an antibiotic material, an antifungal material, an antimicrobrial material, a deodorant material and nitric oxide. The cover may include a pocket for use with an accessory, such as a heater or mapping grid.A method of treating a treatment area on a patient's skin with the treatment device. The treatment device includes a closed treatment volume having polymeric foam ring impregnated with a medicament. The treatment device is attached to the patient's skin, such that the closed treatment volume encloses the treatment area. The medicament is released into the treatment volume to bring the medicament into contact with the treatment area. Additional steps may include inserting a heater into the pocket or inserting the mapping grid into the pocket and tracking the treatment area with the mapping grid.

The invention provides a saline land improvement method and belongs to the technical field of saline land improvement. The saline land improvement method comprises the following steps of locally smashing straws of plants growing in a saline land and then spreading the straws on the saline land, continuing to sequentially spread a composite microbiological material for renovation and urea on the surface of the saline land spread with smashed straws, and plowing and watering the saline land spread with the smashed straws, the composite microbiological material for renovation and the urea on the surface, wherein the composite microbiological material for renovation comprises raw material components: 4-6 parts by weight of organic manure, 2-4 parts by weight of humic acid, 0.7-3 parts by weight of agricultural organic waste, 0.2-0.4 part by weight of marine organic waste, 0.01-0.02 part by weight of liquid fungicide and 0.005-0.01 part by weight of solid fungicide. The saline land improvement method has the advantages of being low in renovation cost, small in working amount, convenient to operate and free of secondary pollution.

A catheter having features configured to provide a substantially uniform flow rate of a fluid exiting the catheter and also exhibits anti-microbial properties. The uniform flow rate features may include one or more of a flow restricting membrane or flow restricting component within an infusion section of the catheter. In other arrangements, exit holes defining the infusion section of the catheter may be configured to provide the desired uniform flow rate over the length of the infusion section. Furthermore, the catheter also includes anti-microbial properties to inhibit the growth of microbes on or within the catheter and, preferably, to inhibit microbe growth in an anatomical region surrounding the catheter. The desired anti-microbial properties may be provided by an anti-microbial layer, anti-microbial materials dispersed within the material from which components of the catheters are constructed, or a combination of anti-microbial layers and embedded anti-microbial materials. In some arrangements, one or more portions of the catheter may be bio-absorbable.

A system for the rapid analysis of microbiological parameters includes a specimen container for containing a liquid sample, a housing having an enclosable chamber shaped for receiving the specimen container, an incubating system mounted within the housing for incubating microbiological materials within the liquid sample, and a spectrophotometer system mounted within the housing for measuring light absorbed, emitted or scattered by the liquid samples as the microbiological materials are incubated by the incubating system over time. The specimen container is filled with a liquid sample to be tested and mixed with a reagent that provides a detectable parameter, and placed inside the apparatus. The incubation system heats and maintains the temperature of the liquid sample within a preset range while the spectrophotometer system propagates light within the specimen container, and monitors and records changes in the light as the light propagates through the container. A continuous non-intrusive monitoring and recording of the test parameter is achieved as the incubation progresses. Any significant deviation of the signal output is an indication of presence of the detectable parameter, while the time taken to reach the significant deviation provides quantification of the microbiological parameter under investigation.

Compositions having antimicrobial activity contain surface functionalized particles comprising an inorganic copper salt which has low water solubility. These types of inorganic salts may also be introduced in porous particles to yield antimicrobial compositions. The compositions may optionally comprise additional antimicrobial agents, salts with high water solubility, organic acids, salts of organic acids and their esters. The compositions may be added to various fluids used in the petroleum extraction industry, or used as coatings on components used in this industry. These antimicrobial materials may be used for reducing both anaerobic and aerobic bacteria and are also useful for reducing corrosion of ferrous components caused by anaerobic bacteria. Although such compositions may be used for any antimicrobial application, and some of the other important uses of these compositions are in wound care, personal care and waste processing.

The invention is directed to efficient methods for depositing highly adherent anti-microbial materials onto a wide range of surfaces. A controlled cathodic arc process is described, which results in enhanced adhesion of silver oxide to polymers and other surfaces, such as surfaces of medical devices. Deposition of anti-microbial materials directly onto the substrates is possible in a cost-effective manner that maintains high anti-microbial activity over several weeks when the coated devices are employed in vivo.

A two-stage, tandem, replaceable filter cartridge assembly includes an outer filter cartridge having a cylindrical shape and defining an axial bore therein, and an inner filter cartridge, also having a cylindrical shape which is received within the axial bore of the outer filter cartridge. The inner filter cartridge may be collapsible so that it can be easily inserted inside the axial bore of the outer filter cartridge, and is expandable so that in normal applications, it rests up against the inner surface of the outer filter cartridge's core, if such is included, or filter medium. One or both of the filter media of the inner and outer cartridges may be formed from an antimicrobial material. In a second embodiment, each of the inner and outer filter cartridges has top and bottom end caps which respectively are structured to mate with one another to form seals therebetween to prevent or minimize the egress of water between the mating top and bottom end caps.

An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from about 60 to about 95 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 0.25 wt % pigment, and about 0.5 to about 3.5 wt % lubricant. The silicone resin may be a dispersion of about 40 to about 60 w / v % of an RTV silicone resin in a solvent, a liquid silicone resin, or a solid silicone resin. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article and permitting the solvent to evaporate. It may also be formed by making a mixture of about 5 to about 12 wt % of an antimicrobial formulation and about 88 to about 95 wt % of a liquid or solid silicone resin and molding, overmolding, or extruding the article from the compounded mixture.

A filter medium capable of removing microorganisms from a fluid such as water. The filter medium includes particles of activated carbon, particles of a substantially insoluble inorganic material having an isoelectric point greater than the fluid being filtered. A low melt index binder, preferably with a melt index of less than about 1 gram per 10 minutes, binds the particles of activated carbon and particles of inorganic material, such that the binder will become tacky at elevated temperatures without becoming sufficiently liquid to substantially wet the particles of activated carbon and inorganic material. An antimicrobial material can be incorporated into the filter to prevent biofilm growth. The use of a biocidal material in combination with the high isoelectric point material provides a trap-and-kill mechanism for microorganism removal.

A process for depositing anti-microbial materials into or onto the surface of a substrate using ionic plasma deposition. The process includes the steps of providing a cathode of target material having anti-microbial potential which is disposed within a partial vacuum, powering the cathode to generate a plasma discharge for ionizing the target material into a plasma of constituent particles. The plasma particles are reacted with ionized gas, and are selected, controlled and directed toward the substrate by electromagnetic fields generated by at least one first anode adjacent to the cathode and at least one second anode positioned adjacent the first anode. Additional anode structures and charged screens provide further control of the plasma constituents. The plasma constituents, comprising the anti-microbial materials, are deposited on the substrate as dispersed ordered structures which form an anti-microbial surface into and onto the substrate.

A needleless valve assembly includes a needleless connector having a housing with an inlet end with an inlet opening and an outlet end with an outlet opening, and a valve disposed in the housing to control passage between the openings. The assembly also includes a collar having an exterior surface and an interior surface, and a first end with a collar opening communicating between the interior surface and the exterior surface and a second end moveably attached to the housing. Further, the assembly includes a barrier disposed across the collar opening with a slit therethrough and including an anti-microbial material. The collar is moveable relative to the housing so that the inlet end of the housing depends past the exterior surface of the collar through the slit in the barrier. A kit may include the assembly and a catheter having a first end attached to the outlet opening.

Sulfur composites and polymeric materials having a high sulfur content and prepared from elemental sulfur as the primary chemical feedstock. The sulfur copolymers are prepared by the polymerization of elemental sulfur with one or more monomers of amines, thiols, sulfides, alkynylly unsaturated monomers, nitrones, aldehydes, ketones, thiiranes, ethylenically unsaturated monomers, or epoxides. The sulfur copolymers may be further dispersed with metal or ceramic composites or copolymerized with elemental carbon, photoactive organic chromophores, or reactive and solubilizing / biocompatible moieties. The sulfur composites and polymeric materials feature the ability self-healing through thermal reformation. Applications utilizing the sulfur composites and polymeric materials may include electrochemical cells, optics, H2S donors and antimicrobial materials.

Contact killing antimicrobial articles, devices and formulations are described which kill microorganisms on contact. The articles, devices or formulations contain a non-leaching antimicrobial material which is a unique combination of an organic matrix having biocidal metallic materials non-leachably associated with the matrix. The antimicrobial material may used to form an antimicrobial coating or layer on a surface of the article or device, or may be dispersed in a vehicle or carrier to form a topical antiseptic or disinfectant, or solid shape having contact killing antimicrobial properties. When a microorganism contacts the article, device, or formulation, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it.

A system is provided for regulating a flow of oxygen to a patient where the system may include an oximeter for measuring the patient's blood oxygen level and / or heart rate; a controller for determining a desired oxygen flow rate based on the patient's blood oxygen level and / or heart rate, and generating a control signal representative of the desired oxygen flow rate; an oxygen flow regulator for dynamically regulating a flow rate of oxygen supplied to the patient responsive to the control signal provided by the controller; an oxygen delivery device; and a transmitter for wirelessly communicating with an electronic medical records system. The oxygen flow regulator may receive oxygen from an oxygen bottle, oxygen mixer, a wall oxygen supply of a healthcare facility, or an oxygen concentrator. One or more of the components of the system may be treated with an antimicrobial material.

Specific transfer methods and articles to impart a metal-ion based antimicrobial finish to recipient textile surfaces. Such treatments preferably comprise silver ions, particularly as constituents of inorganic metal salts or zeolites. In particular, the inventive method involves the application of a solid, inorganic antimicrobial material to a donor substrate (such as a dryer sheet), and the subsequent placement of such a substrate within a tumble drying machine containing textile fabrics and operating the machine. The donor substrate, upon contact with the recipient textile fabrics, transfers antimicrobially effective amounts of the metal-ion based compounds to such recipient fabrics thereby imparting at least a temporary antimicrobial finish over at least a portion of such fabrics. The donor substrates, with either the antimicrobial compound alone or mixed with standard tumble dryer additives (such as perfumes, fabric softeners, fiber lubricants, and the like) are also contemplated within this invention.

The invention relates to polymeric coatings on proppants. These coatings have antimicrobial materials incorporated within these coatings. Preferably the antimicrobial materials have low water solubility. These antimicrobial agents are incorporated as particles whose surfaces are modified or these may also be incorporated within porous particles which are then added to the coating formulations. The antimicrobially active agents are incorporated in a fashion so that they can be released from these coatings in the environment of the proppants.

An intravenous connector is provided having a valve body having first end configured to receive a syringe for administering medicine to a patient; a spike element having a tapered hollow spike terminating in a tip at a first end and having a second end configured for attaching to an intravenous tube, the spike element secured in the valve body such that the tip is disposed proximate the first end of the valve body and the second end of the spike element is located at a second end of the valve body; and a pliable seal member disposed in the valve body around the tapered hollow spike and exposed at the first end of the valve body. An antimicrobial material comprising a silane quaternary ammonium salt is incorporated on or within the seal member and is coated on the valve body and the spike element.

An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a polyurethane resin or polyurethane hybrids, copolymers, or mixtures with other polymers such as polyesters, nitrites, PVC, and synthetic rubber latexes. The antimicrobial formulation is formed from about 60 to about 90 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 2 wt % color and appearance enhancing pigments, about 0.001 to about 2 wt % of surfactants, and about 0.5 to about 10 wt % lubricant. The polyurethane resin may be a nonaqueous or aqueous latex dispersion or a prepolymer that polymerizes when exposed to moisture. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article; if a polyurethane prepolymer is used, the composition is exposed to moisture and if an aqueous or nonaqueous dispersion is used, the water or solvent is evaporated. A coating may also be formed by making a mixture of the antimicrobial formulation and a resin and molding, overmolding, or extruding the article from the compounded mixture.

An expandable, foldable compact shopping bag that includes a decorative outer face that converts into a pocket that holds further expandable, foldable compact shopping bags. The bag decor can match any other article of clothing or bags used by the consumer. The bag can include a thermal layer for the transport of perishable foodstuffs or made of an anti-microbial material. The bag is secured shut when folded through attachment means, such as magnets, snaps, buttons, zippers, hook and loop systems and the like.

The invention describes a usage of a heteroatom doped water-soluble carbon quantum dot serving as a photosensitizer in an antimicrobial material. Various types of heteroatom doped water-soluble carbon quantum dots contain one or more of such heteroatoms as N, S, Si, Se, P, As, Ge, Gd, B, Sb and Te, and the absorption spectrum wavelength of the heteroatom doped water-soluble carbon quantum dot is 300-850 nm. As shown in a research, the heteroatom doped water-soluble carbon quantum dots can efficiently generate active oxygen under the irradiation of visible light, so that the heteroatom doped water-soluble carbon quantum dot has a huge development potential in the application field of photodynamic (PDT) sterilization and disinfection.

A method is provided for depositing a hard wear resistant surface onto a porous or non-porous base material of a medical implant. The wear resistant surface of the medical implant device may be formed by a Laser Based Metal Deposition (LBMD) method such as Laser Engineered Net Shaping (LENS). The wear resistant surface may include a blend of multiple different biocompatible materials. Further, functionally graded layers of biocompatible materials may be used to form the wear resistant surface. Usage of a porous material for the base may promote bone ingrowth to allow the implant to fuse strongly with the bone of a host patient. The hard wear resistant surface provides device longevity, particularly when applied to bearing surfaces such as artificial joint bearing surfaces or a dental implant bearing surfaces. An antimicrobial material such as silver may be deposited in combination with a metal to form an antimicrobial surface deposit.

A composite having a textured surface with multiple protrusions and a bulk portion. The composite includes a polymeric matrix and particles, the major amount of particles being concentrated into the textured surface. The composite can be used as a structural coating, super-repellent material, antireflective material, or antimicrobial material among others.