A manual-reversing insulin uniformly-mixing device comprises a base provided with a boss, a concave rotary table and a uniformly-mixing barrel; a supporting column for supporting the bottom of the concave rotary table is arranged on the base; the edge of the bottom of the concave rotary table is rotatingly connected with the edge of the boss on the base through a rotary shaft, so as to achieve a fact that after the concave rotary table rotates 90 degrees around the rotary shaft, one outer lateral wall of the concave rotary table is fitted with the top of the boss; a medicine basket filled with insulin is arranged in a barrel body; a barrel cover is provided with a motor II; a transmission shaft of the motor II passes through the barrel cover and is connected with the medicine basket, so as to make the medicine basket rotate around a rotary shaft II mounted at the bottom of the barrel body under the action of the motor II. Through a plurality of simple components, a large amount of insulin is mixed uniformly according to a correct method before a patient is injected, and an insulin short supply problem is avoided from appearing.