The invention discloses a preparation method of canned pear in syrup. The method belongs to the technical field of food processing. The method comprises the steps that: (1) vacuuming liquid is injected into pear pieces according to a mass ratio of 1:1.5-3; when a vacuum degree is reduced to 0.07-0.09MPa, vacuuming is carried out for 5-10min, such that vacuumed pear pieces are obtained; and (2) the vacuumed pear pieces are canned, and soup liquid is added; the can is sealed, and is subjected to normal-temperature sterilization for 15-25min under a temperature of 98-100 DEG C; and the can is cooled, such that the canned pear in syrup is obtained. The vacuuming liquid comprises the following components, by mass, 0.05-0.1% of calcium lactate, 0.1-0.3% citric acid, 0.05-0.1% of D-sodium isoascorbate, and balance of water. With the preparation method provided by the invention, a production period is short, manpower and material resources are saved, energy consumption is low, and processing cost is reduced. The method is environment friendly, and is suitable for industrial large-scale productions.