The invention discloses a hot backup method of a VTS multi-sensor information comprehensive processing system. The method comprises the following steps: step one, synchronizing clock; step two, establishing an information corresponding table; step three, establishing a chained topology list; step four, determining a working machine; step five, synchronizing data; step six, switching fault; and step seven, after the equipment fault is recovered, repeating steps three to six, establishing a new chained topology list, and repeatedly and circularly executing to realize automatic monitoring switching of a backup machine. The hot backup of the multi-sensor information comprehensive server is realized, and a reliability requirement on a heartbeat link by the hot backup, the flexibility and uniqueness of the automatic switching of the working machine and the backup machine are comprehensively considered, a closed-loop synchronization mechanism is designed according to a data integrity requirement on the VTS multi-sensor information comprehensive processing, and the high reliability and stability of a VTS system are well guaranteed by adopting a way of taking starting time as unique arbitration decision for the working machine.