This invention belongs to the field of steel
structure building technology, and particularly relates to a connection structure for prefabricated steel structure beams and columns with ultra-large cross-sections. The structure includes: an upper connecting column with a lower supporting column at its bottom; both the upper connecting column and the lower supporting column are hollow square steel tubes; a positioning component fixedly disposed at one end inside the upper connecting column; a clamping component fixedly disposed at one end inside the lower supporting column, which cooperates with the positioning component to clamp the positioning component; and a beam-column connection component fixedly disposed at the outer end of the upper connecting column and / or the lower supporting column, with multiple crossbeams detachably connected to the beam-column connection component. This invention can improve the construction efficiency and
assembly accuracy of steel structure beams and columns.