The invention discloses a piglet antibiotic-free compound feed containing fermented mulberry leaf powder. The piglet antibiotic-free compound feed comprises the following raw materials in parts by weight: 5-20 parts of fermented mulberry leaf powder, 60-65 parts of corn, 10-15 parts of soybean meal, 1-2 parts of extruded soybeans, 1-1.5 parts of whey powder, 1-1.5 parts of odd feed powder, 2-4 parts of fish meal, 1-2 parts of glucose and 2-4 parts of antibiotic-free premix. Wherein the fermented mulberry leaf powder is obtained by cleaning mulberry leaves, airing, shredding, adding bran, uniformly mixing, bagging, fermenting, drying and crushing, the nutritional value can be effectively improved, the process is simple, the production cost is low, and production is facilitated. The piglet antibiotic-free compound feed containing the fermented mulberry leaf powder is of an antibiotic-free formula, is designed according to the characteristics of weaned piglets, can remarkably increase the number of lactobacillus in intestinal tracts and reduce the number of escherichia coli when being used for feeding the piglets, and is lower in feed conversion ratio and lower in diarrhea rate.