44results about How to "More soluble" patented technology

The invention relates to pharmaceutical compositions comprising propylene glycol solvates of APIs.

Novel positive-working photoresist compositions are disclosed. The monomers of the base resin of the resist contain diamondoid-containing pendant groups higher than adamantane in the polymantane series; for example, diamantane, triamantane, tetramantane, pentamantane, hexamantane, etc. The diamondoid-containing pendant group may have hydrophilic-enhancing substituents such as a hydroxyl group, and may contain a lactone group. Advantages of the present compositions include enhanced resolution, sensitivity, and adhesion to the substrate.

The present invention involves a method and apparatus for enhanced recovery of petroleum fluids from the subsurface by injection of a steam and hydrocarbon vaporized solvent in contact with the oil sand formation and the heavy oil and bitumen in situ. Multiple propped hydraulic fractures are constructed from the well bore into the oil sand formation and filled with a highly permeable proppant. Steam, a hydrocarbon solvent, and a non-condensing diluent gas are injected into the well bore and the propped fractures. The injected gas flows upwards and outwards in the propped fractures contacting the oil sands and in situ bitumen on the vertical faces of the propped fractures. The steam condenses on the cool bitumen and thus heats the bitumen by conduction, while the hydrocarbon solvent vapors diffuse into the bitumen from the vertical faces of the propped fractures. The bitumen softens and flows by gravity to the well bore, exposing fresh surface of bitumen for the process to progressively soften and mobilize the bitumen in a predominantly circumferential, i.e. orthogonal to the propped fracture, diffusion direction at a nearly uniform rate into the oil sand deposit. The produced product of oil and dissolved solvent is pumped to the surface where the solvent can be recycled for further injection.

Soluble and stable liquid compositions containing a plant growth regulator selected from the group consisting of cytokinin and a gibberellin, an acid solubilizer such as citric acid, tartaric acid or glycolic acid and a solvent; as well as methods for making and using the composition are disclosed. The compositions improve solubility, handling, stability, safety, as well as activity improvements such as improved plant growth, yield, fruit thinning or sizing and quality. The compositions are soluble and stable by adding an ethoxylated alkyl alcohol wherein the growth regulator is 6-benzyladenine (6-BA) or forchlorfenuron (CPPU) and the ethoxylated alcohol surfactant is C12-15 alkyl alcohol in propylene glycol. The compositions may also contain a cytokinin such as 6-benzyladenine (6-BA) or forchlorfenuron (CPPU) that is increased in solubility and activity and by synergistically combined with GA₃ or GA₄A₇ as well as in storage stability by adding an antioxidant. The compositions are formulated in a ready-to-mix formulation.

The present invention involves a method and apparatus for enhanced recovery of petroleum fluids from the subsurface by injection of a steam and hydrocarbon vaporized solvent in contact with the oil sand formation and the heavy oil and bitumen in situ. Multiple propped hydraulic fractures are constructed from the well bore into the oil sand formation and filled with a highly permeable proppant. Steam, a hydrocarbon solvent, and a non-condensing diluent gas are injected into the well bore and the propped fractures. The injected gas flows upwards and outwards in the propped fractures contacting the oil sands and in situ bitumen on the vertical faces of the propped fractures. The steam condenses on the cool bitumen and thus heats the bitumen by conduction, while the hydrocarbon solvent vapors diffuse into the bitumen from the vertical faces of the propped fractures. The bitumen softens and flows by gravity to the well bore, exposing fresh surface of bitumen for the process to progressively soften and mobilize the bitumen in a predominantly circumferential, i.e. orthogonal to the propped fracture, diffusion direction at a nearly uniform rate into the oil sand deposit. The produced product of oil and dissolved solvent is pumped to the surface where the solvent can be recycled for further injection.

The present invention involves a method and apparatus for enhanced recovery of petroleum fluids from the subsurface by injecting a hydrocarbon solvent vapor in contact with the oil sand formation and the heavy oil and bitumen in situ. Multiple propped vertical hydraulic fractures are constructed from the well bore into the oil sand formation. The hydrocarbon solvent vapor and a non-condensing diluent gas are injected into the well bore, fill the hydraulic fractures, and thus contact and diffuse into the in situ bitumen. The hydrocarbon solvent vapors diffuse into the bitumen from the vertical faces of the propped fractures. The bitumen softens and flows by gravity to the well bore, exposing fresh surface of bitumen for the process to progressively soften and mobilizes the bitumen in a predominantly circumferentially, i.e. orthogonal to the propped fracture, diffusion direction at a nearly uniform rate into the oil sand deposit. The mobile oil may be deasphalted by the condensed solvent, leaving the heavy asphaltenes behind in the oil sand pore space with little loss of inherent fluid mobility in the processed oil sands. The processed product is produced with the dissolved solvent along with a tail diluent gas. The tail diluent gas is enriched with hydrocarbon solvent and re-injected into the process zone and the cycle repeated.

The present disclosure relates to a method for synthesizing ergothioneine or one of the derivatives thereof of following formula (I):

or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in all proportions thereof,

from a compound of betaine type of following formula (II):

or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in all proportions thereof,

by cleavage reaction in the presence of a thiol, at a temperature above or equal to 60° C.

The present disclosure also relates to compounds of formula (II) and the method of synthesis thereof.

The present invention involves a method and apparatus for enhanced recovery of petroleum fluids from the subsurface by injecting a hydrocarbon solvent vapor in contact with the oil sand formation and the heavy oil and bitumen in situ. Multiple propped vertical hydraulic fractures are constructed from the well bore into the oil sand formation. The hydrocarbon solvent vapor and a non-condensing diluent gas are injected into the well bore, fill the hydraulic fractures, and thus contact and diffuse into the in situ bitumen. The hydrocarbon solvent vapors diffuse into the bitumen from the vertical faces of the propped fractures. The bitumen softens and flows by gravity to the well bore, exposing fresh surface of bitumen for the process to progressively soften and mobilizes the bitumen in a predominantly circumferentially, i.e. orthogonal to the propped fracture, diffusion direction at a nearly uniform rate into the oil sand deposit. The mobile oil may be deasphalted by the condensed solvent, leaving the heavy asphaltenes behind in the oil sand pore space with little loss of inherent fluid mobility in the processed oil sands. The processed product is produced with the dissolved solvent along with a tail diluent gas. The tail diluent gas is enriched with hydrocarbon solvent and re-injected into the process zone and the cycle repeated.

The invention relates to a method for recovering low molecular weight lignin from a filtrate, wherein the low molecular weight lignin includes lignin molecules having a molecular weight of 3000 g/mol or lower, wherein the filtrate is obtained from a process where lignin is precipitated from black liquor and the formed precipitate is separated therefrom by filtration resulting in the filtrate including low molecular weight lignin being formed, and wherein the method includes the following steps: a) adjusting the pH of the filtrate to a value of 3-4 for precipitating lignin in the filtrate; b) separating the precipitated lignin from the filtrate; c) reslurrying the separated lignin until the dry solids content of the slurry is 25-40 weight-% and adjusting the pH of the slurry to a value of 2-3; d) washing the slurry; and e) separating the lignin from the slurry.

The present invention provides a polyimide resin, which is prepared by epolycondensing a dianhydride monomer including at least a dianhydride represented by formula (I)

• • wherein R is O or O(CH₂)_nO, n is an integer of 1 to 2 and a diamine monomer represented by formula (II)

H₂N—Ar—NH₂   (II)

wherein Ar is defined as in the text then imidizing the resulting polyamic acid resin to form a polyimide resin. Through using the dianhydride represented by formula (I) as the polymerizing unit, a biphenyl moiety and an ester moiety are introduced into the main chain of the polyimide resin, such that the resulting polyimide resin has lower moisture absorption and smaller linear thermal expansion coefficient and therefore have satisfactory heat resistance and dimensional stability, in addition, become more soluble in organic solvents.

New methods for the refolding of recombinant granulocyte colony stimulating factor (G-CSF) from inclusion bodies are disclosed. The methods comprise two refolding steps. In particular, the methods comprise the solubilising of G-CSF with a solubilising agent, the oxidative refolding (first refolding step) of G-CSF in the presence of the solubilising agent and an oxidizing agent, the efficient removal of the solubilising agent, and a second refolding step to complete the folding of G-CSF in the absence of the solubilising agent. Various methods are described for the efficient removal of the solubilising agent from partially refolded G-CSF.

The invention provides food composition for regulating phlegm-dampness constitution and a preparation method of the food composition. The food composition comprises raw materials as follows: coix seeds, Chinese yam, white hyacinth beans, red beans, broomcorn, black soybeans, peanuts, broad beans, radish seeds, dietary fiber, lotus seeds, seabuckthorn fruits, amomum fruits, Chinese wax gourd peels, Poria cocos, wheat germs, rice and maltodextrin. The preparation method comprises steps as follows: other raw materials except maltodextrin are heated, cooked and mixed uniformly, a paste is obtained and processed by a low-temperature spray drying device, granular powder is prepared, maltodextrin is added to the granular powder, and the food composition is obtained. According to the regulating mechanisms of spleen invigorating, dampness removal, phlegm and turbidity elimination, homology of medicine and food, warming and yang activating for damp evil removal, as well as combination of phlegm-dampness removal and blood circulation promotion for simultaneous removal of turbid phlegm and blood stasis, the food composition with active functions of inhibiting bacteria, reducing blood pressure, resisting cancer, enhancing digestive tract mobility, resisting epinephrine and oxidation, regulating immunity, benefiting the bile, resisting platelet aggregation and the like is obtained.

Pharmaceutical formulations prepared by granulating valganciclovir or a salt thereof, using a nonaqueous solvent or hydro-alcohol.

The invention provides novel LRP5-binding polypeptides, and more specifically novel LRP5-binding immunoglobulin single variable domain constructs which can inhibit Wnt signaling pathways. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as cancer.

This disclosure relates to a process for polymerization, and in particular to minimizing undesired polymerization reactions downstream of a polymerization reaction zone, for instance by use of a quenching agent that enables fast reaction rates with active polymerization catalyst in the polymerization effluent, so as to quench the catalyst quickly, thereby preventing uncontrolled polymerization reactions. A preferred quenching agent is methanol. Also provided are means for treating polymer recycle streams containing oxygenates, which may result from the use of such quench agents, particularly in polymerization processes including polyene (e.g., diene) monomers.

A device (e.g., a vending machine) and method for preparing a consumable beverage include mixing an agglomerated natural milk powder having a scorched particle mass not greater than fifteen milligrams with hot water to produce the consumable beverage. The hot water and milk powder may be mixed prior to or during their placement of the beverage in a beverage cup, such as part of operation of a vending machine. Alternatively, the hot water and milk powder may be mixed with one or more additional ingredients, such as coffee, tea, cocoa powder, and/or sugar, to produce the beverage. Further, the hot water and milk powder may be whipped together or with an additional ingredient to produce a foaming beverage, such as cappuccino.

Compounds of Formula I

wherein R¹, A, R², R³, R⁴, R⁵, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.

Compounds of Formula I

wherein R¹, A, R², n, R³, m, R⁴, R⁵ and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.