The utility model relates to a weight detection loading device of a weighing sensor, which comprises a bearing base, a weighing sensor main body and a loading disc, the top of the weighing sensor main body is fixedly connected with a mounting box, a bidirectional screw rod is rotatably connected in the mounting box, two threaded sections of the bidirectional screw rod are respectively sleeved with a nut in a threaded manner, and the top end of each nut is fixedly provided with a sliding block. Sliding grooves are formed in the positions, corresponding to the sliding blocks, of the top of the mounting box, the sliding blocks are arranged in the corresponding sliding grooves in a sliding mode, the top ends of the sliding blocks stretch out of the sliding grooves and are fixedly connected with locking plates, and a plurality of locking rods are arranged on the opposite sides of the two locking plates. A plurality of second through holes are formed in the side, close to the locking rod, of the positioning seat, a plurality of second blind holes are formed in the other side of the positioning seat, mounting plates are fixedly arranged on the left side and the right side of the outer top of the carrying disc, and a plurality of third through holes are formed in the mounting plates. According to the utility model, the weighing sensor main body and the loading disc can be independently and conveniently disassembled, assembled and replaced, and the weighing sensor is more practical.