The invention relates to a larval micropterus salmoides food conversion domestication method. The method is characterized by comprising the following steps of (1) selecting and setting a domesticationpool; 2) preparing before stocking; 3) putting fries; 4) food conversion domestication, specifically, I, feeding live freshwater rotifers; II, after 1-3 days, mixing frozen rotifers with water for feeding; III, after 1-2 days, carrying out feeding through mixed feed, wherein the mixed feed is obtained by mixing the frozen rotifers with water and artificial compound granular baits according to themass ratio into paste, and sequentially reducing the number of the frozen rotifers according to the proportion of 1: 1, 0.75: 1 and 0.5: 1 until the frozen rotifers are completely replaced by the artificial compound granular baits; and IV, after 1-2 days, carrying out feeding for 1-2 days through the artificial compound granular baits; 5) daily management; and (6) putting fries into a pond, namely transferring the successfully-fed micropterus salmoides fries to an outdoor soil pond for culture, wherein the culture baits are all artificial compound granular baits. According to the method, through continuously adjusting the proportion of the mixed feed for food conversion domestication, the larval micropterus salmoides fries are induced to be fed with the artificial compound granular baitsin an initial stage, the feeding cost is reduced, and the survival rate in the domestication and food conversion process is increased.