The invention relates to the technical field of commercial heavy truck cooling systems, and discloses a guard-plate-free high-reliability commercial vehicle cooling module integrated structure which comprises a radiator, an intercooler, a condenser, a cooling fan protective cover and an insect-proof net, a water inlet chamber is arranged on the upper portion of the radiator, and a water outlet chamber is arranged on the lower portion of the radiator. The upper left portion of the side, close to the water inlet chamber, of the radiator is fixedly connected with the intercooler through a first bolt, the upper right portion of the side, close to the water inlet chamber, of the radiator is fixedly connected with the intercooler through a second bolt, and the lower left portion of the side, close to the water outlet chamber, of the radiator is connected with the intercooler through a metal shock pad. The lower right portion of one side close to the water outlet chamber is connected with the intercooler through a metal shock pad, the metal shock pad is fixedly connected with the water outlet chamber of the radiator through a plug pin, and the two sides of the radiator are each provided with a baffle for supporting the radiating core and releasing thermal expansion stress of the core. According to the guard-plate-free high-reliability commercial vehicle cooling module integrated structure, the reliability of the cooling module can be greatly improved, the lightweight requirement is met, and the weight and the cost are greatly reduced.