The invention discloses a computer case structure with the dust removal performance, and relates to the technical field of computer equipment. The computer case structure comprises a case body, a containing plate is fixedly connected to the left side of the inner wall of the case body, a bottom box is fixedly connected to the bottom of the inner wall of the case body, a partition plate is fixedly connected between the top and the bottom of the inner wall of the bottom box, an exhaust fan is fixedly connected to the left side of the bottom of the inner wall of the bottom box, a suction pipe is communicated with a suction opening of the exhaust fan, one end of the suction pipe is communicated with a suction plate, a top box is fixedly connected with the right side of the inner wall of the case body, and a first bevel gear is fixedly connected to an output shaft of a motor. According to the computer case with the dust removal performance, dust removing can be conducted on the interior of the case effectively, it is guaranteed that elements inside the computer case can work normally, the performance of the computer is greatly improved, unnecessary waste is reduced, dust removal is very convenient to achieve, and meanwhile the stability of the device is effectively improved, the work efficiency is greatly improved, and the cost is reduced.