A method of providing ventricular support for patients experiencing an acute
myocardial infarction (AMI) by performing a coronary intervention procedure. The method including inserting a mechanical circulatory support device into the vasculature of a patient; delivering the mechanical circulatory support device within the vasculature into a heart of the patient; operating the mechanical circulatory support device for a support period; and measuring a
sympathetic nerve activity (CSNA) of the patient during the mechanical circulatory support. A reduction in the recorded CSNA levels during the mechanical circulatory support device is reduced after 60 minutes of the mechanical circulatory support by between about 40.8% to about 54.2% as compared to the CSNA levels at the
initiation of the mechanical circulatory support.