404 results about "Dyspepsias" patented technology

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.

The invention discloses a traditional Chinese medicine combination and a preparation method thereof for dysentery treatment; the traditional Chinese medicine combination mainly includes the following raw medicines: the rhizome of Chinese goldthread, bighead atractylodes rhizome, rhizoma atractylodis, mangnolia officinalis, medicated leaven, sunburn frankincense, sunburn myrrh, rhizoma alismatis, plantain seed, fructus evodiae, dried tangerine, angelica, white paeony root, scutellaria baicalensis, oyster, red halloysite, starwort root, rhizoma cyperi, gorgon fruit, Chinese yam, drgon's bones, radix sophorae flavescentis, ash bark and codonopsis pilosula and the like. The traditional Chinese medicine combination can be prepared into any type of common oral preparation according to the conventional traditional Chinese medicine preparation method. The invention can significantly improve the symptoms of diarrhea, dysentery, bellyache, tenesmus, dyspepsia, difficult diet and loss of appetite, and also has definite clinical curative effect, significant curative and quick effect. As the traditional Chinese medicine combination basically combines medicinal and edible medicine sources specified in the National Formulary, the traditional Chinese medicine combination has low cost and basically has no toxic and side effect.

The invention discloses a clostridium butyricum having a diarrhea treating effect. The strain is named as clostridium butyricum Cb-2 which is conserved in China Center for Type Culture Collection with the conservation number of CCTCC M2011384, in November 9th, 2011. A test proves that the clostridium butyricum disclosed by the invention has strong acid producing capability especially butyric acidproducing capability; and the clostridium butyricum has obvious effects on diseases, such as intestinal tract flora infection, acute and chronic diarrhea, irritable bowel syndrome and non-ulcer dyspepsia, caused by various reasons, and has no toxicity and harm. Thus, the clostridium butyricum or clostridium butyricum powder disclosed by the invention is used as a raw material for preparing a micro-ecological preparation and used for replacing sodium butyrate to be applied; and when a specific application is carried out, a clostridium butyricum preparation can be singly used as an active component to be prepared into the micro-ecological preparation together with corn starch, or, the clostridium butyricum preparation is mixed with at least one of other bacterial preparations and the corn starch to prepare a composite micro-ecological preparation.

A once-a-day oral milnacipran modified release formulation has been developed. The formulation comprises an extended release dosage unit (optionally containing the immediate release portion) coated with delayed release coating. The milnacipran composition, when administered orally, first passes through the stomach releasing from zero to less than 10% of the total milnacipran dose and then enters the intestines where drug is released slowly over an extended period of time. The release profile is characterized by a 0.05-4 hours lag time period during which less than 10% of the total milnacipran dose is released followed by a slow or extended release of the remaining drug over a defined period of time. The composition provides in vivo drug plasma levels characterized by Tmax at 4-10 hours and an approximately linear drop-off thereafter and Cmax below 3000 ng / ml, preferably below 2000 ng / ml, and most preferably below 1000 ng / ml. The composition provides a therapeutic effect over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, nausea, vomiting, headache, tremulousness, anxiety, panic attacks, palpitations, urinary retention, orthostatic hypotension, diaphoresis, chest pain, rash, weight gain, back pain, constipation, vertigo, increased sweating, agitation, hot flushes, tremors, fatigue, somnolence, dyspepsia, dysoria, nervousness, dry mouth, abdominal pain, irritability, and insomnia.

The invention discloses an edible traditional Chinese medicine composition and a preparation method thereof. The edible traditional Chinese medicine composition is prepared from 6 to 30 parts by weight of white hyacinth bean, 6 to 30 parts by weight of dioscorea rhizome, 6 to 30 parts by weight of white poria, 6 to 30 parts by weight of coix seed, 6 to 30 parts by weight of semen nelumbinis, 6 to 30 parts by weight of gordon euryale seed, 3 to 15 parts by weight of dried ginger, 4 to 20 parts by weight of haw, 4 to 20 parts by weight of germinated barley, 3 to 15 parts by weight of inner membrane of chicken gizzard, and 3 to 15 parts by weight of orange peel. The edible traditional Chinese medicine composition has functions of invigorating spleen and tonifying qi, excreting dampness and stopping diarrhea, warming the middle warmer and promoting appetite, improving intestinal immunity, adjusting intestinal functions and promoting digestion. The edible traditional Chinese medicine composition is mainly used for treating children's diarrhoea caused by spleen deficiency, anorexia, dyspepsia and drug-induced diarrhea. The edible traditional Chinese medicine composition has mild properties and flavor, can be used as a medicine and a food, and has no toxic and side effects, a sweet smell, an excellent taste and a wide application range.

The invention relates to a Chinese medicinal composition for treating gastrointestinal tract diseases, which is prepared from the following raw materials (by weight ratio): banksia rose, linaloe, bitter orange, magnolia bark each 2-20 parts, Chinese date 10-60 parts, musk 0.1-0.8 part, defatted powder of croton seed 1-10 parts, sandalwood 1-10 parts, rheum officinale 1-10 parts, rhizome of Sichuan lovage 1-10 parts and cinnabar 1-10 parts.

Pharmaceutical composition for regulation of pancreatic juice secretion characterized by comprising a lisophosphatidic acid (LPA) receptor modulator. Since an LPA receptor modulator has an effect of regulating the secretion of pancreatic juice, a compound acting on this receptor is useful in treating diseases in association with disorders in pancreatic juice secretion. For example, an LPA receptor agonist is useful in treating and / or preventing pancreatic diseases and obesity, while an LPA receptor antagonist is useful in treating and / or preventing maldigestion, constipation, diarrhea and cibophobia.

The novel positively charged prodrugs of acetylsalicylic acid and its analogues in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of ASA or its analogues,(for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and push the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl acetylsalicylate.AcOH, diffuses through human skin -400 times faster than acetylsalicylic acid itself and -100 times faster than ethyl acetylsalicylate. In plasma, 80% of these pro-drugs can change back to the drug in a few minutes. The pro-drugs can be used medicinally in treating any aspirin-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of aspirin, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enable the aspirin in the blood to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of aspirin.

The invention discloses a compound traditional Chinese medicine for diminishing inflammation, checking diarrhea and relieving pain. The compound traditional Chinese medicine consists of the following active pharmaceutical ingredients by weight:10-14 grams of poria, 8-12 grams of rhizoma atractylodis macrocephalae, 10-14 grams of semen dolichoris album, 8-12 grams of dioscorea opposita, 6-10 grams of myristica fragrans, 10-14 grams of cortex magnoliae officinalis, 8-12 grams of rhizoma atractylodis, 8-12 grams of endoconcha sepiae, 6-10 grams of pericarpium citri reticulatae, 4-8 grams of pinellia tuber, 8-12 grams of inula britannica, 8-12 grams of reddle, 8-12 grams of endothelium corneum gigeriae galli, 8-12 grams of fructus amomi, 8-12 grams of fructus crataegi, 8-12 grams of fructus hordei germinatus, 8-12 grams of semen raphani, 6-10 grams of massa medicata fermentata, 8-12 grams of root of pilose asiabell, 8-12 grams of ixeris denticulata, 8-12 grams of anemone chinensis, 8-12 grams of herba taraxaci, 6-10 grams of fructus litseae, 4-8 grams of lignum dalbergiae odoriferae, 4-8 grams of cortex fraxini, 4-8 grams of pericarpium granati, 8-12 grams of halloysit, 4-8 grams of citrus medica linn, 4-8 grams of fructus citri sarcodactylis, 6-10 grams of corydalis turtschaninovii bess and 6-10 grams of fructus meliae toosendan. The compound traditional Chinese medicine has obvious effects in treating chronic gastritis, dyspepsia, diarrhea and abdominal pain. The compound traditional Chinese medicine has the advantages of short treatment time, good treatment effect, no side effect and the like.

The novel positively charged prodrugs of acetylsalicylic acid and its analogues in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of ASA or its analogues,(for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and push the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl acetylsalicylate. AcOH, diffuses through human skin -400 times faster than acetylsalicylic acid itself and ˆ¼100 times faster than ethyl acetylsalicylate. In plasma, 80% of these pro-drugs can change back to the drug in a few minutes. The pro-drugs can be used medicinally in treating any aspirin-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of aspirin, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enables the aspirin to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of aspirin.

The invention relates to a traditional Chinese medicinal composition for treating gastrointestinal tract, in particular to a medicinal composition for treating gastrointestinal tract diseases such as acute and chronic gastritis, enteritis, gastric ulcer, superficial gastritis, gastric acid, gastrectasia, indigestion and the like. The invention also relates to a preparation of the medicinal composition. The traditional Chinese medicinal composition for treating gastrointestinal tract comprises the medicaments in percentage by weight: 10-25 parts of red ginseng, 10-23 parts of poria, 8-20 parts of bighead atractylodes rhizome, 10-25 parts of rhizoma ligustici wallichii, 10-25 parts of rhizoma atractylodis, 10-25 parts of cyperus rotundus, 10-25 parts of medicated leaven, 10-25 parts of gardenia, 10-23 parts of betelnut, 8-20 parts of radix aucklandiae, 5-15 parts of liquorice, 5-8 parts of malt and 10-25 parts of hawthorn. The medicinal composition for treating the gastrointestinal tract is orally taken and has the efficacies of regulating the flow of qi, comforting the stomach, diminishing inflammation, killing pain, repairing gastrointestinal mucosa and ulceration, enhancing gastrointestinal motility, adjusting gastric acid secretion, promoting digestive absorption and the like.

The invention relates to a traditional Chinese medicine preparation having functions of neutralizing the effect of alcoholic drink, reducing blood fat and protecting the liver and cardio-cerebral blood vessels, which comprises the following compositions: 20 to 80 percent of pollen pini, 10 to 70 percent of kudzu root extract, 5 to 50 percent of nutmeg extract and 5 to 30 percent of auxiliary materials. The traditional Chinese medicine preparation is health-care food prepared from pure natural food, namely the pollen pini, kudzu roots and nutmeg which are taken as main raw materials by a reasonable formula, specially aims to people suffering from chronic alcohol drinking, fat people and patients suffering from hypertension, hyperlipemia and hyperglycemia and chronic diseases, and achieves the aim of protecting chemical liver damage by protecting the liver and resisting lipid overoxidation damage of the liver caused by alcoholism. The pollen pini contains rich antioxidative substances, and can lighten lipid overoxidation damage of alcohol on the liver, strengthen metabolism of fatty acid in hepatocyte, and reduce fat deposition in the hepatocyte; the nutmeg has the function of regulating spleen and stomach; and the kudzu roots also have the function of relieving cerebral vasospasm, so that the traditional Chinese medicine preparation achieves the aim of relieving symptoms such as headache, stomach upset, dyspepsia and poor health after drinking.

The present invention provides conformationally-defined macrocyclic compounds that bind to and / or are functional modulators of the motilin receptor including subtypes, isoforms and / or variants thereof. These macrocyclic compounds, at a minimum, possess adequate pharmacological properties to be useful as therapeutics for a range of disease indications. In particular, these compounds are useful for treatment and prevention of disorders characterized by hypermotilinemia and / or gastrointestinal hypermotility, including, but not limited to, diarrhea, cancer treatment-related diarrhea, cancer-induced diarrhea, chemotherapy-induced diarrhea, radiation enteritis, radiation-induced diarrhea, stress-induced diarrhea, chronic diarrhea, AIDS-related diarrhea, C. difficile associated diarrhea, traveller's diarrhea, diarrhea induced by graph versus host disease, other types of diarrhea, dyspepsia, irritable bowel syndrome, chemotherapy-induced nausea and vomiting (emesis) and post-operative nausea and vomiting and functional gastrointestinal disorders. In addition, the compounds possess utility for the treatment of diseases and disorders characterized by poor stomach or intestinal absorption, such as short bowel syndrome, celiac disease and cachexia. The compounds also have use for the treatment of inflammatory diseases and disorders of the gastrointestinal tract, such as inflammatory bowel disease, ulcerative colitis, Crohn's disease and pancreatitis. Accordingly, methods of treating such disorders and pharmaceutical compositions including compounds of the present invention are also provided.

The invention specifically provides a foodstuff, medical formulated foodstuff, specific medical formulated foodstuff, health-care product and drug for patients with disorders in intestinal microecology, belonging to the technical field of both medicinal and edible prescriptions and new resource food. Prescriptions for intestinal-microecology regulating preparations in the invention are developed according to the physical characteristics of people with disorders in intestinal microecology and on the basis of reasonable combination of quintessential theories of traditional Chinese medicine and modern bioscientific progress. Specifically, the intestinal-microecology regulating preparations are prepared from probiotic powder obtained after vacuum freeze drying and adjuvants consisting of prebiotics, cereal fiber and multiple natural plant essences of medicinal and edible traditional Chinese medicines and the like through mixing, granulation and other processes, and are capable of forming probiotic intestinal barriers, promoting spleen yang, invigorating the spleen, regulating middle energizer, preventing inflammations, relieving pain and eliminating dampness and heat. The intestinal-microecology regulating preparations can effectively improve gastrointestinal diseases like diarrhea, enteritis and dyspepsia caused by disorders in intestinal microecology; the preparations can improve insomnia dreaminess due to the tranquillizing effect of ginseng; and kudzu vine roots and turmeric in the preparations can relieve or neutralize the effect of alcohol, protect the liver, and alleviate discomfort caused by alcohol.

A Chinese medicine in the form of injection or the orally taken preparations for treating insomnia, functional indigestion and constipation is prepared from 9 Chinese-medicinal materials including cyperus tuber, wild jujube, tuckahoe, scutellaria root, etc. Its preparing process is also disclosed.

The objective of the invention is to provide a medicinal and edible composition having no toxic or side effect and especially a composition capable of replenishing qi, invigorating the spleen and nourishing the stomach. The composition is prepared from the following ingredients: ginseng roots, poria cocos, Chinese yam, lotus seeds, coix seeds, white hyacinth beans and wheat flour. One or a plurality of the following substances also can be added into the traditional Chinese medicinal composition: tangerine peel, perilla, fructus amomi, prepared licorice roots, bighead atractylodes rhizomes, platycodon roots, jujubes, sesame, ginseng leaves, haws, chicken gizzard-membrane, malt, hyacinth-bean flowers and semen raphani. The invention also relates to the application of the composition containing the ingredients by a certain weight ratio in preparing health care food or medicines or products having functions of preventing and treating chronic gastritis, peptic ulcer, chronic diarrhea, functional dyspepsia, ulcerative colitis and syndrome of weakness of the spleen and the stomach, replenishing qi, invigorating the spleen, nourishing the stomach and relieving abdominal distension and pain and loss of appetite caused by the chronic gastritis, gastroduodenal ulcer, the chronic diarrhea, the functional dyspepsia and the ulcerative colitis.

The invention relates to the field of medicine synthesis and discloses an exenatide analog. The exenatide analog disclosed by the invention is used for preparing a medicine composition for treating diseases. The invention discloses application of medicine composition in preparing medicines for treating at least one of the following diseases: type-II diabetes, impaired glucose tolerance, type-I diabetes, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive disorder, atherosclerosis, myocardial infarction, coronary heart diseases, cardiovascular diseases, stroke, inflammatory intestinal tract syndrome and / or dyspepsia or gastric ulcer, hepatic fibrosis diseases and pulmonary fibrosis diseases.

The invention discloses a Chinese medicine composition for treating esophageal cancer and a preparation method thereof. The Chinese medicine composition is mainly formed by the following raw medicine materials: coix seed, figwort root, Taraxacum officinale root, rhizoma belamcandae, Vietnamese sophora root, Chinese lobelia, lithospermum, Poria cocos, white paeony root, indigo naturalis, aspongopus, ground beetle, prepared frankincense, prepared myrrh, pangolin scale, dried tangerine peel, fructus amomi, common burreed rhizome, zedoary, Rhizoma acori Graminei, dalbergia wood, agilawood, Ligusticum wallichii and the like. The Chinese medicine composition of the invention can be prepared into any kind of common oral preparation according to the conventional Chinese medicine preparation method. The invention has the advantages that symptoms such as growth, development, diffusion and transfer of esophageal cancer tumors, difficulty in swallowing, hiccup, vomitting, chocking, dyspepsia, emaciation and the like are obviously improved, the clinical curative effect is exact, the curative effect is obvious and the rapid effect is obtained. Moreover, the Chinese medicine composition is basically combined by homologous plant food medicines regulated in National Formulary, thereby having the advantages of low cost, basically no toxic side effect and the like.

The novel positively charged pro-drugs of ibuprofen in the general formula (I) ''Structure 1'' were designed and synthesized. The compounds of the general formula (I) ''Structure 1'' indicated above can be prepared from functional derivatives of ibuprofen, (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl 2-(p-isobutylphenyl) propionate.AcOH, diffuses through human skin -250 times faster than ibuprofen itself and -125 times faster than ethyl 2-(p-isobutylphenyl) propionate. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any ibuprofen-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of ibuprofen, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enable the ibuprofen to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of ibuprofen.

The invention provides sialic acid-added milk powder with an easy digestion function for premature infants and a preparation method thereof, and relates to the technical field of foods. The milk powder is prepared from the following raw materials: skim milk powder, lecithin, maltodextrin, immune globulin, refined palm olein, vitamin complex, prebiotics, minerals, alpha-whey protein, lactotransferrin, ferrous gluconate, bifidobacterium, sialic acid, edible vegetable oil mixture, beta-galactosidase, tryptophan, threonine and cystine. Compositions of the formula of the milk powder for premature infants is closer to breast milk, memory and intelligence level of premature infants can be improved by the sialic acid ingredient added into the milk powder, and nutrition essential to premature infant growth can be provided by optimizing the proportion of ingredients. The milk powder can be easily digested and absorbed, and can be used for improving the resistance of premature infants and reducing the phenomena of internal heat and iron-deficiency anemia caused by dyspepsia.

The invention discloses a medicine compound for curing tummy bug, which including following ingredients and proportion: bismuth aluminic acid 100-300 shares, heavy magnesium carbonate 100-600 shares, sodium bicarbonate 100-400 shares, liquorice extractive powder 100-500 shares, frank mouse lippich 1-50 shares, fennel powder 1-50 shares, aloe powder 1-50 shares or / and grassleaved sweetflag rhizome 1-50 shares. It also discloses the manufacturing method for the medicine, the compound medicine is one compound preparation resisting acid and protecting gastric mucosa, it can be applied to cure stomach and duodenum abscess, chronic superficial gastritis, overmuch stomach acid, and nerve indigestion and so on.

The present invention relates to a Chinese medicine pill preparation-Ganjiwan with the functions of promoting digestion, invigorating spleen, regulating stomach, promoting flow of qi, eliminating stagnated food and expelling, intestinal parasites for curing the diseases of dyspepsia, indigestion, abdominal distention, constipation, abdominal pain due to enterositosis and other diseases. Said medicine pill preparation is made up by using 10 Chinese medicinal materials of crataegus fruit, barley sprout, medicated leaven, gizzard lining, magnolia bark and others through the processes of drying, pulverizing, seiving, mixing, making pills by mixing medical powder with honey, sterilizing and packaging.

The invention discloses a spleen-invigorating and dampness-eliminating traditional Chinese medicine extract and a preparation method and an application thereof as well as a spleen-invigorating and dampness-eliminating cream. The spleen-invigorating and dampness-eliminating Chinese medicine extract is prepared by extracting the following raw materials in parts by weight: 3 to 4 parts of poria, 4 to 5 parts of yams, 3 parts of coix seeds, 3 to 4 parts of malt, and 1 part of tangerine peels. The poria, yams, coix seeds, malt, and tangerine peels are added to achieve the efficacies of invigorating the spleen and strengthening the middle energizer, and benefiting Qi and eliminating dampness, and can be used for alleviating the loss of appetite, abdominal distension, loose stools, dyspepsia, fatigue and weakness and other symptoms caused by the excessive dampness due to deficiency in spleen. The traditional Chinese medicinal materials in a formula are mutually synergized in property, flavor and function aspects, and the traditional Chinese medicine extract can be taken by people having excessive dampness due to deficiency in spleen.

Oral pharmaceutical, nutraceutical, health foods and medical device compositions based on polysaccharides from Opuntia Ficus Indica cladodes in combination with other active substances are useful for the prevention or treatment of GERD (Gastro-Esophageal Reflux Disease), gastric esophagitis and related diseases (e.g. dyspepsia, esophagitis, esofageal tumour, gastro-intestinal symptoms, chronic pharyngitis, Barrett's esophagus, esophageal adenocarcinoma, GERD-related pulmonary symptoms).

The invention discloses a medicine for treating gastrointestinal diseases by utilizing biological live bacteria, which is prepared from the following substances: 1 to 6 weight portions of oligoisomaltose, 1 to 6 weight portions of glucose, as well as 1 to 10 hundred million CFU / gram of bifidobacteria, 1 to 10 hundred million CFU / gram of lactobacilli and 1 to 10 hundred million CFU / gram of probiotics which take the total weight of the oligoisomaltose and the glucose as a radix number, wherein the probiotics are at least one of bacillus, lactococcus and enterococcus. The medicine is based on a modern microecology theory, adopts a probiotic live bacteria preparation to treat diseases such as gastritis, gastric ulcer, enteritis, diarrhea, constipation, indigestion, abdominal distension, diarrhea, intestinal cancer, acute and chronic hepatitis, low immunity and the like, and has the advantages of reliable action, broad function, safe use, no any toxic side effect and irritation, convenient administration and carrying and the like.

The present invention provides a food. The food comprises the following raw materials in percentages by weight: 10%-90% of wheat flour, 3%-25% of a traditional Chinese medicinal composition, 0.01%-15% of a swelling agent, 1%-35% of a sweetening agent, 1%-35% of oil, 0.1%-5% of edible salt and 0.001%-10% of essences. The traditional Chinese medicinal composition is characterized by comprising the following raw materials in parts by weight: 1-15 parts of ginsengs, 3-25 parts of poria cocos, 5-50 parts of Chinese yams, 2-25 parts of lotus seeds, 3-50 parts of coix seeds and 3-25 parts of semen lablab album. The food has functions of preventing and treating chronic gastritis, peptic ulcers, chronic diarrhea, functional dyspepsia, ulcerative colitis, spleen and stomach weakness syndromes, abdominal distension or abdominal pains, and inappetence, and benefits qi, strengthens spleen and nourishes stomach.

The present invention provides a paederia scandens extract and applications thereof. According to the present invention, the paederia scandens extract provides important application values in treatment of food retention, diarrhea, dyspepsia and other gastrointestinal tract diseases; and the compound traditional Chinese medicine comprising the paederia scandens extract, dried ginger, radix aconiti lateralis preparata, alisma orientalis and glucose oxidase provides good market prospects in the fields of inhibition and killing of pathogenic microorganisms, treatments of food retention, diarrhea, dyspepsia and other gastrointestinal tract diseases, promotion of animal growth, improvement of feed conversion rate, and the like.

The invention discloses a novel stomach invigorating tangerine peel powder and a preparation method and an application of the novel stomach invigorating tangerine peel powder; the novel stomach invigorating tangerine peel powder comprises the components by mass percent: 5-10% of tangerine peel extract powder, 10-20% of pomegranate bark charcoal powder and 70-85% of tangerine peel charcoal powder. The tangerine peel extract powder is tangerine peel alcohol extract, and the novel stomach invigorating tangerine peel powder is prepared by concentrating the tangerine peel extract powder, adding a right amount of carrier into the concentrated tangerine peel extract powder, mixing, drying at low temperature and crushing into powder. The obtained powder contains the tangerine peel extract within the mass fraction range of 0.1-0.5g tangerine peel extract / g powder; the best mass fraction of the tangerine peel extract powder is 0.5g tangerine peel extract / g powder; the pomegranate bark charcoal powder is pomegranate bark calcined charcoal powder; and the tangerine peel charcoal powder is residue calcined charcoal powder obtained after tangerine peel is extracted by alcohol. The novel stomach invigorating tangerine peel powder is suitable for relieving or preventing the symptoms such as gastrointestinal discomfort, decreased intake, dyspepsia and the like caused by acute and chronic gastroenteritis of pigs, and can be used for a long time as feed additive.