98 results about "Dyspepsias" patented technology

The invention relates to the field of medicine synthesis, and discloses a GCG-GLP-1 dual agonist compound. The GCG-GLP-1 dual-agonist compound provided by the invention is used for preparing a pharmaceutical composition for treating diseases, and the application of the pharmaceutical composition in preparing a medicine for treating at least one of the following diseases, the diseases include type II diabetes mellitus, impaired glucose tolerance, type I diabetes mellitus, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive impairment, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, stroke, inflammatory bowel syndrome and / or dyspepsia or gastric ulcer, hepatic fibrosis disease and pulmonary fibrosis disease.

The invention relates to the field of medicine synthesis, and discloses a GLP-1 / GIP / GCG tri-agonist compound. The GLP-1 / GIP / GCG three-agonist compound is used for preparing a medicine composition for treating diseases, and the application of the medicine composition in preparing a medicine for treating at least one of the following diseases, namely, the GLP-1 / GIP / GCG three-agonist compound, and the GLP-1 / GIP / GCG three-agonist compound. The diseases include type II diabetes mellitus, impaired glucose tolerance, type I diabetes mellitus, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive impairment, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, stroke, inflammatory bowel syndrome and / or dyspepsia or gastric ulcer, hepatic fibrosis disease and pulmonary fibrosis disease.

The invention relates to the field of medicine synthesis, and discloses a GLP-1 / GIP / GCG tri-agonist compound. The GLP-1 / GIP / GCG three-agonist compound is used for preparing a medicine composition for treating diseases, and the application of the medicine composition in preparing a medicine for treating at least one of the following diseases, namely, the GLP-1 / GIP / GCG three-agonist compound, and the GLP-1 / GIP / GCG three-agonist compound. The diseases include type II diabetes mellitus, impaired glucose tolerance, type I diabetes mellitus, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive impairment, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, stroke, inflammatory bowel syndrome and / or dyspepsia or gastric ulcer, hepatic fibrosis disease and pulmonary fibrosis disease.

The invention relates to a traditional Chinese medicine composition for treating functional dyspepsia combined with anxiety and depression and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 200-781 parts of rhizoma pinellinae praeparata, 50-365 parts of coptis chinensis, 100-521 parts of scutellaria baicalensis, 150-625 parts of rhizoma zingiberis, 50-313 parts of ginseng, 100-417 parts of liquorice, 150-625 parts of Chinese dates and 150-521 parts of immature bitter orange. The traditional Chinese medicine composition has a good effect of treating functional dyspepsia combined with anxiety and depression, and the preparation method of the traditional Chinese medicine composition is simple and suitable for large-scale production and popularization.

The invention relates to the field of medicine synthesis, and discloses a GLP-1 / GCG dual-agonist compound. The GLP-1 / GCG dual-agonist compound provided by the invention is used for preparing a pharmaceutical composition for treating diseases, and application of the pharmaceutical composition in preparation of a medicine for treating at least one of the following diseases, the diseases include type II diabetes mellitus, impaired glucose tolerance, type I diabetes mellitus, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive impairment, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, stroke, inflammatory bowel syndrome and / or dyspepsia or gastric ulcer, hepatic fibrosis disease and pulmonary fibrosis disease.

The invention relates to the technical field of medicines, and discloses an application of a traditional Chinese medicine composition in a humanized flora transplantation model.The application comprises the following steps that an experimental body is pretreated through sterile feeding or broad-spectrum antibiotics, then coprophilous fungus suspension of a functional dyspepsia patient is transplanted, and the humanized flora transplantation model is constructed; acquiring physiological data of the humanized flora transplantation model, and performing intervention on the traditional Chinese medicine composition after the humanized flora transplantation model is completed; acquiring physiological data of the traditional Chinese medicine composition intervened humanized flora transplantation model, and analyzing an evaluation result of the traditional Chinese medicine composition intervened humanized flora transplantation model by combining the evaluation parameters of the humanized flora transplantation model. The bottleneck that the traditional animal model is greatly different from the human microflora and the curative effect and the mechanism are difficult to transform is overcome, so that the research result is closer to the clinical practice, and the molecular mechanism of the traditional Chinese medicine composition is reliably revealed.

The invention discloses a multi-layer multi-release metagen composition and application thereof in quickly promoting defecation, lubricating intestinal tracts, relieving intestinal problems such as flatulence, stomachache, diarrhea, constipation, irritable bowel syndrome and inflammatory bowel disease, maintaining intestinal flora balance, repairing intestinal tracts, repairing intestinal mucosa health, relieving dyspepsia and improving gastrointestinal functions.

The invention relates to a compound probiotic formula, a preparation and application of the compound probiotic formula. The compound probiotic formula is prepared from bifidobacterium animalis HN019, bifidobacterium animalis Bb-12, bifidobacterium breve M-16V, lactobacillus rhamnosus HN001 and lactobacillus acidophilus NCFM. The ratio of the viable count of the bifidobacterium animalis HN019 to the viable count of the bifidobacterium animalis Bb-12 to the viable count of the bifidobacterium breve M-16V to the viable count of the lactobacillus rhamnosus HN001 to the viable count of the lactobacillus acidophilus NCFM is 2.5 to 1.2 to 1.3 to 2.5 to 2.5. The traditional Chinese medicine composition has the advantages of helping to establish intestinal flora balance, improving immunity, preventing infectious diseases, regulating immune balance, preventing and relieving eczema and allergy, bidirectionally regulating diarrhea and constipation, relieving gastrointestinal function discomfort symptoms, improving poor appetite, anorexia and dyspepsia, improving children crying and screaming at night and poor sleep, improving children growth and development retardation, and improving children immunity. Social emotion behaviors of children are improved, and attention deficits are improved; the probiotic composition can coexist and symbiotic, induces an organism to establish intestinal flora balance, relieves food allergy symptoms, and improves social emotion problems caused by food allergy.

The invention belongs to the field of biological pharmacy, and particularly relates to a phenolic acid composition and application thereof in promoting digestion. According to the invention, monophenolic acid for improving dyspepsia is found through a single-component phenolic acid experiment, and then a phenolic acid compound with a synergistic effect is searched in a compounding manner, so that unexpectedly, the combination of two phenolic acids with the best digestion promoting effect cannot realize the effect optimization; on the contrary, syringic acid with the worst digestion promoting effect is compounded with other phenolic acids, so that the synergistic digestion promoting effect is achieved, the effect of a positive medicine can be achieved, and a potential optional medicine is provided for improving dyspepsia.

The invention belongs to the technical field of traditional Chinese medicine preparations, and provides a traditional Chinese medicine granule composition based on rhizoma polygonati and a preparation method and application thereof. A three-layer intelligent response structure design is adopted, a 80-300 nm rhizoma polygonati nano core is prepared through an anti-solvent precipitation technology, a calcium alginate gel buffer layer containing probiotic nutritional factors is constructed through an ionic crosslinking technology, a pH response shell layer is prepared through a fluidized bed coating technology, and the release rate lt in gastric juice is achieved; the cumulative release rate gt in intestinal juice is 10%; according to the invention, the rhizoma polygonati polysaccharide and probiotic nutritional factors are added into the preparation, the precise intestinal targeted release performance is 80%, the drug loading capacity is 15-35%, the coating efficiency is 85-95%, and the technical problems that a traditional rhizoma polygonati preparation is poor in stability, effective components are damaged by gastric acid, and the bioavailability is low are solved; the traditional Chinese medicine composition can be used for treating diseases such as weakness of the spleen and the stomach, functional dyspepsia and dysbacteriosis of intestinal flora, and has wide application value.

This invention relates to a traditional Chinese medicine preparation for treating functional dyspepsia and its preparation method. The traditional Chinese medicine preparation is made from the following raw materials in parts by weight: Pinellia ternata 200-781 parts, Coptis chinensis 50-365 parts, Scutellaria baicalensis 100-521 parts, Zingiber officinale 150-625 parts, Panax ginseng 50-313 parts, Glycyrrhiza uralensis 100-417 parts, Ziziphus jujuba 150-625 parts, and Citrus aurantium 150-521 parts. The traditional Chinese medicine preparation of this invention has a good therapeutic effect on functional dyspepsia, and the preparation method of this traditional Chinese medicine preparation is simple and suitable for large-scale production and promotion.

The present invention relates to the field of pharmaceutical synthesis. A GLP-1 / Gcg dual-agonist compound is disclosed. The GLP-1 / Gcg dual-agonist compound is used for preparing a pharmaceutical composition for treating disease. Use of the pharmaceutical composition in the preparation of a drug for treating at least one of the following diseases: type-II diabetes, impaired glucose tolerance, type-I diabetes, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive disorders, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, strokes, inflammatory bowel syndrome and / or dyspepsia or gastric ulcers, hepatic fibrosis disease, and pulmonary fibrosis disease.

The invention discloses a traditional Chinese medicine compound composition for treating functional dyspepsia and a preparation method and application thereof. The traditional Chinese medicine compound composition is prepared from 5-20 parts of gordon euryale seeds, 6-12 parts of Chinese yams, 10-30 parts of astragalus membranaceus, 10-30 parts of roasted rhizoma atractylodis macrocephalae, 10-20 parts of smoked plums, 3-15 parts of pericarpium citri reticulatae viride, 10-40 parts of malt, 6-12 parts of roasted endothelium corneum gigeriae galli, 10-20 parts of honey-fried licorice roots and the like. The traditional Chinese medicine composition is prepared according to the theory of treatment based on syndrome differentiation, has the functions of strengthening the spleen and stomach, promotes digestion and absorption, and has an exact treatment effect on related symptoms caused by dyspepsia. Most medicinal materials are medicinal and edible, have small toxic and side effects and are safe and reliable to take.

The invention provides a traditional Chinese medicine composition formula for improving intestinal flora and application thereof, and relates to the technical field of traditional Chinese medicine, and the traditional Chinese medicine composition formula is prepared from the following raw materials: bighead atractylodes rhizome, poria cocos, pericarpium citri reticulatae, fructus amomi, fried malt, fried rice sprout, lotus seed, gordon euryale seed, dandelion, agastache rugosus, eupatorium, fried white hyacinth bean, medicated leaven, semen raphani and astragalus membranaceus. According to the invention, the number of beneficial bacteria in intestinal tracts can be increased, multi-target regulation of intestinal flora can be carried out, growth of harmful bacteria can be inhibited, diversity of intestinal flora can be improved, structural balance of flora can be recovered, the effect is comprehensive, and the effect is remarkable; the used raw materials are all medicinal and edible or common traditional Chinese medicines, are high in safety and have no obvious toxic or side effects; the traditional Chinese medicine composition is suitable for different types of intestinal flora disorder patients, and especially has a good treatment effect on functional dyspepsia, inflammatory diseases, irritable bowel syndrome and other diseases.

The application provides a pharmaceutical composition for functional dyspepsia and a preparation method and application thereof, and belongs to the technical field of medicines, and the pharmaceutical composition comprises the following components: Aucklandia, Atractylodes, Mentha, Agastache, Citrus aurantium, Uncaria, Tribulus terrestris, Guangdong Shenqu, Chrysanthemum, Poria cocos, Radix Trichosanthis, Coix seed, Magnolol, Imperatorin, Isoimperatorin, Oxypeucedanin, Ferulic acid, Vanillic acid, p-Coumaric acid and Puerarin. The pharmaceutical composition comprises traditional Chinese medicine components and compounds, the components interact with each other, the effect of the pharmaceutical composition on improving functional dyspepsia can be improved, and meanwhile, the pharmaceutical composition has excellent stability.

The application provides application of a Baoji oral liquid composition in preparation of a functional dyspepsia medicine, and relates to the technical field of medicines. The application is based on the Baoji oral liquid, and it is found that the Baoji oral liquid has a remarkable effect on treating functional dyspepsia, especially cisplatin-induced functional dyspepsia. Specifically, the Baoji oral liquid can rapidly restore body weight, significantly improve body weight gain, steadily promote food intake, significantly improve gastric emptying rate and intestinal propulsion rate, protect the gastric mucosa layer, reduce inflammatory cell infiltration, repair the mucosa layer and muscle layer, improve the expression of serum gastrin and motilin, and improve the expression level of IL-4 in the gastric tissue and reduce the expression level of IL-1beta. The Baoji oral liquid has remarkable efficacy when applied in preparation of a functional dyspepsia medicine.

The present application belongs to the field of biopharmacy, and particularly relates to a phenolic acid composition and application thereof in promoting digestion. The present application firstly finds a single phenolic acid for improving dyspepsia through single-component phenolic acid experiments, then attempts to find a phenolic acid compound with a synergistic effect through compounding, and surprisingly, the combination of two phenolic acids with the best effect on promoting digestion cannot achieve the best effect optimization, but eugenol with the worst effect on promoting digestion achieves a synergistic effect on promoting digestion through compounding with other phenolic acids, and can achieve the effect of a positive drug, which provides a potential alternative drug for improving dyspepsia.

The invention discloses a traditional Chinese medicine composition for treating diabetes and complications thereof, a preparation and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. According to the traditional Chinese medicine composition, the symptoms of liver-spleen disharmony, phlegm stagnation and qi stagnation and blood stasis are taken as main symptoms according to traditional Chinese medicine differentiation. The symptoms include dry and bitter mouth, impatience and irritability, dyspepsia, fatigue and hypodynamia, insomnia and dreaminess, chest and hypochondrium swelling pain, heavy body, obesity, medium and large tongue body, light red tongue, greasy fur, fine and smooth pulse and the like, and patients with abnormal blood glucose. The formula has the functions of improving insulin resistance, regulating blood sugar metabolism, improving microcirculation, protecting pancreas islet beta cells and the like, and can improve and enhance related organs of a human body after being taken persistently. The formula is more precise and appropriate in compatibility and takes all the components into consideration. The traditional Chinese medicine composition can widely play a main or auxiliary treatment role in diabetes with multiple situations at present. Compared with common blood-glucose-reducing western medicines and insulin, the traditional Chinese medicine preparation is small in toxic and side effects and free of obvious adverse effects after being taken for a long time.

The invention relates to the technical field of medicines, and discloses an application of a traditional Chinese medicine composition in serum neurotransmitter, which comprises the following steps: selecting 6-8 weeks old mice to establish a normal model, a chronic fatigue syndrome model and a functional dyspepsia model; the method comprises the following steps: sampling blood from mice of a normal model, a chronic fatigue syndrome model and a functional dyspepsia model to respectively obtain a normal blood sample, a CFS blood sample and an FD blood sample, and performing protein precipitation operation to obtain normal deproteinized supernatant, CFS deproteinized supernatant and FD deproteinized supernatant; separating by using a reversed-phase chromatographic column, and then carrying out mass spectrometric detection to respectively obtain a normal serum neurotransmitter mass spectrogram, a CFS serum neurotransmitter mass spectrogram and an FD serum neurotransmitter mass spectrogram; and carrying out concentration value calculation and rhythm fluctuation analysis to respectively obtain a neurotransmitter function index and a rhythm stability quantitative score. Therefore, the action mechanism of the serum neurotransmitter of the traditional Chinese medicine composition can be clearly and quantitatively represented.

The utility model relates to a multifunctional cup for oral nutrition supplement patients, which comprises a cup body and a cup cover and further comprises a base fixedly connected with the bottom of the cup body. The controller is arranged in the base; the stirring module is arranged in the base; the heating module is arranged in the base; and the timing module is arranged in the base. Compared with the prior art, a nutrient solution in the cup is heated and kept warm through the heating module, the optimal taking temperature of an oral nutrition preparation is controlled to be 35-38 DEG C, stimulation to gastrointestinal tracts is effectively avoided, and diarrhea is prevented; the stirring assembly is used for stirring the nutrient solution in the cup, so that the phenomenon that the oral nutrient solution is caked and cannot reach a nutrition target value required by an organism or causes dyspepsia and digestive tract intolerance is avoided; a user can conveniently record the preparation time of the nutrient solution through the timing module, so that the prepared oral nutrient solution can be stored at normal temperature for not more than 4 hours and refrigerated for not more than 24 hours to avoid pollution and deterioration.

Provided herein is a bulk composition comprising the trihydrate form of (3S, 4R, 3′R)-6-[4-(4-amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1-yl]-hexanoic acid 1-azabicyclo[2.2.2]oct-3′-yl ester di-hydrochloride salt. Provided are also pharmaceutical compositions and dosage forms comprising the trihydrate form, and methods and uses for treating a gastrointestinal disorder in a subject with the trihydrate form. In some embodiments, the gastrointestinal disorder is gastroesophageal reflux disease (GERD), dyspepsia (such as functional dyspepsia or functional motility disorder), gastroparesis, paralytic ileus, post-operative ileus, emesis, nausea, heartburn, intestinal pseudo-obstruction, irritable bowel syndrome (IBS), constipation, enteral feeding intolerance (EFI), or esophagitis. In some embodiments, the gastrointestinal disorder is post-operative ileus, chronic grass sickness, constipation, megacolon, gastritis, gastrointestinal stasis, or abomasal emptying defect.

The present application belongs to the technical field of traditional Chinese medicine, and specifically discloses a traditional Chinese medicine composition for treating children's functional dyspepsia, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw medicinal materials by weight: Fructus Aurantii Immaturus 5-20 parts, Magnolia officinalis 5-20 parts, Forsythia suspensa 5-30 parts, Dendrobium 5-30 parts, Atractylodes macrocephala 5-20 parts, and Glycyrrhiza 5-30 parts. The pharmacological experiment results show that the traditional Chinese medicine composition has the effects of improving gastrointestinal motility and regulating gastrointestinal hormone secretion, has a significant therapeutic effect on children's functional dyspepsia, has stable curative effect, and has a small dosage. Meanwhile, the present application has the advantages of simple process operation, low cost, good controllability and stability, and is suitable for industrialized mass production.

The present invention relates to a Chinese medicine composition for treating functional dyspepsia, which is prepared from the following Chinese medicine raw materials: pinellia, scutellaria, coptis, dried ginger, codonopsis, amomum, rhubarb, curcuma, magnolia bark, white peony root, corydalis, liquorice, jujube. The preparation method is to decoct in water for multiple times, filter, collect the filtrate, and prepare the corresponding preparation. The preferred preparation is a granule. The Chinese medicine composition has excellent clinical effects in treating functional dyspepsia, especially for patients showing symptoms of cold and heat, liver and stomach disharmony, spleen deficiency and qi stagnation, epigastric fullness or distending pain, poor appetite, dry throat, intestinal rumbling and loose stools, pale tongue with yellow or greasy fur, and stringy and thin pulse, and can also improve mental symptoms such as anxiety and depression related to functional dyspepsia.

The invention relates to oral probiotic hydrogel as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing inulin-modified thiolated polysaccharide with a probiotic liquid, and quickly crosslinking to form probiotic hydrogel, so as to construct a colon-targeted probiotic delivery system; the system can effectively protect the probiotics from passing through the upper digestive tract, and realizes targeted release of the probiotics at the colon part by using a dual mechanism that the inulin is specifically ingested by the probiotics in the colon and the disulfide bond is easily reduced and disassembled by reduced glutathione (GSH) in the colon. The oral probiotic hydrogel disclosed by the invention is applied to preparation of medicines for preventing and treating irritable bowel syndrome, diarrhea, constipation, dyspepsia, inflammatory bowel disease, colon cancer, diabetes mellitus, obesity and hypercholesteremia.

The invention provides a medicine composition for invigorating stomach and dispelling cold as well as a preparation and application thereof, and the medicine composition is prepared from the following raw materials in parts by weight: 20-30 parts of gypsum rubrum, 10-15 parts of fructus amomi rotundus, 10-15 parts of fructus piperis longi powder, 10-15 parts of pomegranate seeds, 10-15 parts of flos carthami, 10-15 parts of radix aucklandiae, 10-15 parts of coriander, 10-15 parts of radix inulae inula and 10-15 parts of pawpaw, the preparation method of the fructus piperis longi powder comprises the following steps: crushing fructus piperis longi, pre-soaking, adding mesoporous silica nanoparticles, adding an ethanol aqueous solution, adjusting the pH value, performing ultrasonic-assisted extraction, filtering, purifying, concentrating and drying to obtain the fructus piperis longi powder; amomum kravanh powder is extracted with the assistance of a deep eutectic solvent, and the content of effective components of the medicine is increased through the preparation method. The pharmaceutical composition disclosed by the invention is scientific in formula and capable of effectively treating sour regurgitation of stomach, gastric ulcer, dyspepsia and inappetence due to the synergistic effect of all the components, and has clinical medication value.

The application relates to the technical field of medicines, and discloses application of a traditional Chinese medicine composition in serum neurotransmitters, which comprises the following steps: selecting 6-8-week-old mice to establish normal models, chronic fatigue syndrome models and functional dyspepsia models; blood sampling is conducted on the mice of the normal models, the chronic fatigue syndrome models and the functional dyspepsia models to obtain normal blood samples, CFS blood samples and FD blood samples respectively; protein precipitation operation is conducted to obtain normal deproteinized supernatants, CFS deproteinized supernatants and FD deproteinized supernatants; separation is conducted by using a reversed-phase chromatographic column, and then mass spectrometry is conducted to obtain normal serum neurotransmitter mass spectra, CFS serum neurotransmitter mass spectra and FD serum neurotransmitter mass spectra respectively; concentration value calculation and rhythm fluctuation analysis are conducted to obtain a neurotransmitter function index and rhythm stability quantitative score respectively. Therefore, the mechanism of the traditional Chinese medicine composition in serum neurotransmitters is clearly quantitatively characterized.

The present invention relates to the field of pharmaceutical combination components and discloses a GLP-1 / Gcg dual agonist compound. The GLP-1 / Gcg dual agonist compound described above is used for manufacturing a pharmaceutical composition for treating diseases. The pharmaceutical composition is used for manufacturing a medicament for treating at least one of diseases including type 2 diabetes, impaired glucose tolerance, type 1 diabetes, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive impairment, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, stroke, inflammatory bowel syndrome and / or indigestion or gastric ulcer, liver fibrosis and pulmonary fibrosis.

Contemplated test kits and methods for food sensitivity are based on rational-based selection of food preparations with established discriminatory p-value. Particularly preferred kits include those with a minimum number of food preparations that have an average discriminatory p-value of ≤0.07 as determined by their raw p-value or an average discriminatory p-value of ≤0.10 as determined by FDR multiplicity adjusted p-value. In further contemplated aspects, compositions and methods for food sensitivity are also stratified by gender to further enhance predictive value.

The invention relates to the technical field of traditional Chinese medicine, in particular to Jianqu and a processing method thereof, and the Jianqu comprises the following raw materials and auxiliary materials: polygonum hydropiper, eupatorium, artemisia apiacea, semen armeniacae amarae, phaseolus calcaratus, fructus aurantii (stir-fried with bran), betel nut powder, rhizoma cyperi powder, magnolia officinalis powder, mint powder, rice sprout powder, malt powder, cinnamon powder, perilla powder, hawthorn (stir-fried), rhizoma atractylodis, radix angelicae, pericarpium citri reticulatae, pogostemon cablin, liquorice, common vladimiria root, wheat bran and flour. According to the Jianqu disclosed by the invention, the herba eupatorii which also has the functions of relieving exterior syndrome and resolving dampness, can promote digestive juice secretion and does not contain toxicity is used for replacing xanthium sibiricum, and the formula does not contain the xanthium sibiricum with toxicity, so that the original effects of improving dyspepsia and relieving gastrointestinal discomfort can be well maintained and even improved; moreover, the injury to the liver can be well avoided, and the safety is better.

The invention discloses a medicinal moxa composition for preventing and treating migraine and dyspepsia stomachache. The medicinal moxa composition comprises gypsum, ginseng, radix angelicae and moxa. Based on the theory that the stomach is mainly accepted and the spleen is mainly transported and transformed, the medicinal moxa composition disclosed by the invention starts from the stomach channel of foot yangming, has the effects of clearing heat, nourishing yin, invigorating the spleen, replenishing qi, regulating qi, relieving pain and the like, and can be used for improving the symptoms of migraine and dyspepsia abdominal pain at the same time. Gypsum has the effects of clearing heat and purging fire, ginseng has the effects of tonifying qi and spleen, radix angelicae has the effects of dispelling wind and relieving pain, moxa has the effects of warming channels and expelling cold and promoting blood circulation to remove meridian obstruction, and the four medicines are compatible to form a balanced system for clearing heat and nourishing yin, invigorating spleen and replenishing qi and regulating qi to relieve pain. The medicinal folium artemisiae argyi composition disclosed by the invention can be used for remarkably reducing the vasospasm degree of a migraine patient and improving the gastrointestinal motility function of a patient suffering from dyspepsia abdominal pain at the same time.