386 results about "Dyspepsias" patented technology

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.

The invention discloses a traditional Chinese medicine combination and a preparation method thereof for dysentery treatment; the traditional Chinese medicine combination mainly includes the following raw medicines: the rhizome of Chinese goldthread, bighead atractylodes rhizome, rhizoma atractylodis, mangnolia officinalis, medicated leaven, sunburn frankincense, sunburn myrrh, rhizoma alismatis, plantain seed, fructus evodiae, dried tangerine, angelica, white paeony root, scutellaria baicalensis, oyster, red halloysite, starwort root, rhizoma cyperi, gorgon fruit, Chinese yam, drgon's bones, radix sophorae flavescentis, ash bark and codonopsis pilosula and the like. The traditional Chinese medicine combination can be prepared into any type of common oral preparation according to the conventional traditional Chinese medicine preparation method. The invention can significantly improve the symptoms of diarrhea, dysentery, bellyache, tenesmus, dyspepsia, difficult diet and loss of appetite, and also has definite clinical curative effect, significant curative and quick effect. As the traditional Chinese medicine combination basically combines medicinal and edible medicine sources specified in the National Formulary, the traditional Chinese medicine combination has low cost and basically has no toxic and side effect.

The invention discloses a clostridium butyricum having a diarrhea treating effect. The strain is named as clostridium butyricum Cb-2 which is conserved in China Center for Type Culture Collection with the conservation number of CCTCC M2011384, in November 9th, 2011. A test proves that the clostridium butyricum disclosed by the invention has strong acid producing capability especially butyric acidproducing capability; and the clostridium butyricum has obvious effects on diseases, such as intestinal tract flora infection, acute and chronic diarrhea, irritable bowel syndrome and non-ulcer dyspepsia, caused by various reasons, and has no toxicity and harm. Thus, the clostridium butyricum or clostridium butyricum powder disclosed by the invention is used as a raw material for preparing a micro-ecological preparation and used for replacing sodium butyrate to be applied; and when a specific application is carried out, a clostridium butyricum preparation can be singly used as an active component to be prepared into the micro-ecological preparation together with corn starch, or, the clostridium butyricum preparation is mixed with at least one of other bacterial preparations and the corn starch to prepare a composite micro-ecological preparation.

The invention discloses an edible traditional Chinese medicine composition and a preparation method thereof. The edible traditional Chinese medicine composition is prepared from 6 to 30 parts by weight of white hyacinth bean, 6 to 30 parts by weight of dioscorea rhizome, 6 to 30 parts by weight of white poria, 6 to 30 parts by weight of coix seed, 6 to 30 parts by weight of semen nelumbinis, 6 to 30 parts by weight of gordon euryale seed, 3 to 15 parts by weight of dried ginger, 4 to 20 parts by weight of haw, 4 to 20 parts by weight of germinated barley, 3 to 15 parts by weight of inner membrane of chicken gizzard, and 3 to 15 parts by weight of orange peel. The edible traditional Chinese medicine composition has functions of invigorating spleen and tonifying qi, excreting dampness and stopping diarrhea, warming the middle warmer and promoting appetite, improving intestinal immunity, adjusting intestinal functions and promoting digestion. The edible traditional Chinese medicine composition is mainly used for treating children's diarrhoea caused by spleen deficiency, anorexia, dyspepsia and drug-induced diarrhea. The edible traditional Chinese medicine composition has mild properties and flavor, can be used as a medicine and a food, and has no toxic and side effects, a sweet smell, an excellent taste and a wide application range.

The invention relates to a Chinese medicinal composition for treating gastrointestinal tract diseases, which is prepared from the following raw materials (by weight ratio): banksia rose, linaloe, bitter orange, magnolia bark each 2-20 parts, Chinese date 10-60 parts, musk 0.1-0.8 part, defatted powder of croton seed 1-10 parts, sandalwood 1-10 parts, rheum officinale 1-10 parts, rhizome of Sichuan lovage 1-10 parts and cinnabar 1-10 parts.

The novel positively charged prodrugs of acetylsalicylic acid and its analogues in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of ASA or its analogues,(for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and push the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl acetylsalicylate.AcOH, diffuses through human skin -400 times faster than acetylsalicylic acid itself and -100 times faster than ethyl acetylsalicylate. In plasma, 80% of these pro-drugs can change back to the drug in a few minutes. The pro-drugs can be used medicinally in treating any aspirin-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of aspirin, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enable the aspirin in the blood to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of aspirin.

The invention discloses a compound traditional Chinese medicine for diminishing inflammation, checking diarrhea and relieving pain. The compound traditional Chinese medicine consists of the following active pharmaceutical ingredients by weight:10-14 grams of poria, 8-12 grams of rhizoma atractylodis macrocephalae, 10-14 grams of semen dolichoris album, 8-12 grams of dioscorea opposita, 6-10 grams of myristica fragrans, 10-14 grams of cortex magnoliae officinalis, 8-12 grams of rhizoma atractylodis, 8-12 grams of endoconcha sepiae, 6-10 grams of pericarpium citri reticulatae, 4-8 grams of pinellia tuber, 8-12 grams of inula britannica, 8-12 grams of reddle, 8-12 grams of endothelium corneum gigeriae galli, 8-12 grams of fructus amomi, 8-12 grams of fructus crataegi, 8-12 grams of fructus hordei germinatus, 8-12 grams of semen raphani, 6-10 grams of massa medicata fermentata, 8-12 grams of root of pilose asiabell, 8-12 grams of ixeris denticulata, 8-12 grams of anemone chinensis, 8-12 grams of herba taraxaci, 6-10 grams of fructus litseae, 4-8 grams of lignum dalbergiae odoriferae, 4-8 grams of cortex fraxini, 4-8 grams of pericarpium granati, 8-12 grams of halloysit, 4-8 grams of citrus medica linn, 4-8 grams of fructus citri sarcodactylis, 6-10 grams of corydalis turtschaninovii bess and 6-10 grams of fructus meliae toosendan. The compound traditional Chinese medicine has obvious effects in treating chronic gastritis, dyspepsia, diarrhea and abdominal pain. The compound traditional Chinese medicine has the advantages of short treatment time, good treatment effect, no side effect and the like.

The invention specifically provides a foodstuff, medical formulated foodstuff, specific medical formulated foodstuff, health-care product and drug for patients with disorders in intestinal microecology, belonging to the technical field of both medicinal and edible prescriptions and new resource food. Prescriptions for intestinal-microecology regulating preparations in the invention are developed according to the physical characteristics of people with disorders in intestinal microecology and on the basis of reasonable combination of quintessential theories of traditional Chinese medicine and modern bioscientific progress. Specifically, the intestinal-microecology regulating preparations are prepared from probiotic powder obtained after vacuum freeze drying and adjuvants consisting of prebiotics, cereal fiber and multiple natural plant essences of medicinal and edible traditional Chinese medicines and the like through mixing, granulation and other processes, and are capable of forming probiotic intestinal barriers, promoting spleen yang, invigorating the spleen, regulating middle energizer, preventing inflammations, relieving pain and eliminating dampness and heat. The intestinal-microecology regulating preparations can effectively improve gastrointestinal diseases like diarrhea, enteritis and dyspepsia caused by disorders in intestinal microecology; the preparations can improve insomnia dreaminess due to the tranquillizing effect of ginseng; and kudzu vine roots and turmeric in the preparations can relieve or neutralize the effect of alcohol, protect the liver, and alleviate discomfort caused by alcohol.

A Chinese medicine in the form of injection or the orally taken preparations for treating insomnia, functional indigestion and constipation is prepared from 9 Chinese-medicinal materials including cyperus tuber, wild jujube, tuckahoe, scutellaria root, etc. Its preparing process is also disclosed.

The objective of the invention is to provide a medicinal and edible composition having no toxic or side effect and especially a composition capable of replenishing qi, invigorating the spleen and nourishing the stomach. The composition is prepared from the following ingredients: ginseng roots, poria cocos, Chinese yam, lotus seeds, coix seeds, white hyacinth beans and wheat flour. One or a plurality of the following substances also can be added into the traditional Chinese medicinal composition: tangerine peel, perilla, fructus amomi, prepared licorice roots, bighead atractylodes rhizomes, platycodon roots, jujubes, sesame, ginseng leaves, haws, chicken gizzard-membrane, malt, hyacinth-bean flowers and semen raphani. The invention also relates to the application of the composition containing the ingredients by a certain weight ratio in preparing health care food or medicines or products having functions of preventing and treating chronic gastritis, peptic ulcer, chronic diarrhea, functional dyspepsia, ulcerative colitis and syndrome of weakness of the spleen and the stomach, replenishing qi, invigorating the spleen, nourishing the stomach and relieving abdominal distension and pain and loss of appetite caused by the chronic gastritis, gastroduodenal ulcer, the chronic diarrhea, the functional dyspepsia and the ulcerative colitis.

The invention discloses a Chinese medicine composition for treating esophageal cancer and a preparation method thereof. The Chinese medicine composition is mainly formed by the following raw medicine materials: coix seed, figwort root, Taraxacum officinale root, rhizoma belamcandae, Vietnamese sophora root, Chinese lobelia, lithospermum, Poria cocos, white paeony root, indigo naturalis, aspongopus, ground beetle, prepared frankincense, prepared myrrh, pangolin scale, dried tangerine peel, fructus amomi, common burreed rhizome, zedoary, Rhizoma acori Graminei, dalbergia wood, agilawood, Ligusticum wallichii and the like. The Chinese medicine composition of the invention can be prepared into any kind of common oral preparation according to the conventional Chinese medicine preparation method. The invention has the advantages that symptoms such as growth, development, diffusion and transfer of esophageal cancer tumors, difficulty in swallowing, hiccup, vomitting, chocking, dyspepsia, emaciation and the like are obviously improved, the clinical curative effect is exact, the curative effect is obvious and the rapid effect is obtained. Moreover, the Chinese medicine composition is basically combined by homologous plant food medicines regulated in National Formulary, thereby having the advantages of low cost, basically no toxic side effect and the like.

The invention provides sialic acid-added milk powder with an easy digestion function for premature infants and a preparation method thereof, and relates to the technical field of foods. The milk powder is prepared from the following raw materials: skim milk powder, lecithin, maltodextrin, immune globulin, refined palm olein, vitamin complex, prebiotics, minerals, alpha-whey protein, lactotransferrin, ferrous gluconate, bifidobacterium, sialic acid, edible vegetable oil mixture, beta-galactosidase, tryptophan, threonine and cystine. Compositions of the formula of the milk powder for premature infants is closer to breast milk, memory and intelligence level of premature infants can be improved by the sialic acid ingredient added into the milk powder, and nutrition essential to premature infant growth can be provided by optimizing the proportion of ingredients. The milk powder can be easily digested and absorbed, and can be used for improving the resistance of premature infants and reducing the phenomena of internal heat and iron-deficiency anemia caused by dyspepsia.

The invention discloses a medicine compound for curing tummy bug, which including following ingredients and proportion: bismuth aluminic acid 100-300 shares, heavy magnesium carbonate 100-600 shares, sodium bicarbonate 100-400 shares, liquorice extractive powder 100-500 shares, frank mouse lippich 1-50 shares, fennel powder 1-50 shares, aloe powder 1-50 shares or/and grassleaved sweetflag rhizome 1-50 shares. It also discloses the manufacturing method for the medicine, the compound medicine is one compound preparation resisting acid and protecting gastric mucosa, it can be applied to cure stomach and duodenum abscess, chronic superficial gastritis, overmuch stomach acid, and nerve indigestion and so on.

The invention discloses a medicine for treating gastrointestinal diseases by utilizing biological live bacteria, which is prepared from the following substances: 1 to 6 weight portions of oligoisomaltose, 1 to 6 weight portions of glucose, as well as 1 to 10 hundred million CFU/gram of bifidobacteria, 1 to 10 hundred million CFU/gram of lactobacilli and 1 to 10 hundred million CFU/gram of probiotics which take the total weight of the oligoisomaltose and the glucose as a radix number, wherein the probiotics are at least one of bacillus, lactococcus and enterococcus. The medicine is based on a modern microecology theory, adopts a probiotic live bacteria preparation to treat diseases such as gastritis, gastric ulcer, enteritis, diarrhea, constipation, indigestion, abdominal distension, diarrhea, intestinal cancer, acute and chronic hepatitis, low immunity and the like, and has the advantages of reliable action, broad function, safe use, no any toxic side effect and irritation, convenient administration and carrying and the like.

The invention discloses a novel stomach invigorating tangerine peel powder and a preparation method and an application of the novel stomach invigorating tangerine peel powder; the novel stomach invigorating tangerine peel powder comprises the components by mass percent: 5-10% of tangerine peel extract powder, 10-20% of pomegranate bark charcoal powder and 70-85% of tangerine peel charcoal powder. The tangerine peel extract powder is tangerine peel alcohol extract, and the novel stomach invigorating tangerine peel powder is prepared by concentrating the tangerine peel extract powder, adding a right amount of carrier into the concentrated tangerine peel extract powder, mixing, drying at low temperature and crushing into powder. The obtained powder contains the tangerine peel extract within the mass fraction range of 0.1-0.5g tangerine peel extract/g powder; the best mass fraction of the tangerine peel extract powder is 0.5g tangerine peel extract/g powder; the pomegranate bark charcoal powder is pomegranate bark calcined charcoal powder; and the tangerine peel charcoal powder is residue calcined charcoal powder obtained after tangerine peel is extracted by alcohol. The novel stomach invigorating tangerine peel powder is suitable for relieving or preventing the symptoms such as gastrointestinal discomfort, decreased intake, dyspepsia and the like caused by acute and chronic gastroenteritis of pigs, and can be used for a long time as feed additive.

Disclosed are methods for the prevention or treatment of a disease or infection caused by or associated with H. Pylori in a subject infected by H. Pylori, the method comprising orally administering a halogenated salicylanilide such as niclosamide to the subject. The method may be used for the prevention or treatment of, for example dyspepsia, gastritis, peptic ulcer disease, premalignant gastric lesions, gastric cancer and gastric mucosa-associated lymphoid tissue (MALT) lymphoma.

The invention provides a combined drug of pantoprazole and domperidone and in particular provides application of pantoprazole and domperidone to preparing combined injections for treating gastric ulcer, duodenal ulcer, gastro-esophageal reflux diseases or functional dyspepsia. The invention also provides the combined injections for treating gastric ulcer, duodenal ulcer, gastro-esophageal reflux diseases or functional dyspepsia, including different specifications of unit preparations, pantoprazole and domperidone for simultaneous, respective or successive administration and preparations prepared by pharmaceutically acceptable vectors. The weight ratio of pantoprazole and domperidone is 1:1-5:1, and the pantoprazole and domperidone contain excipients, stabilizing agents, etc. Through combined injection administration, the invention improves the bioavailability of pantoprazole and domperidone and ensures the treatment effects to be obviously better.

The invention discloses a nutritional rice flour for infants and a preparation method thereof, which comprises the following components in terms of mass percentage: 60-65% of brown rice flour; 20-24% of sugar; 10-15% of protein powder; ‑2%; minerals 1‑2%; the infant rice flour also includes compound probiotics and compound prebiotics. The invention uses organic rice as the main raw material and adds other nutrients, changes the single nutritional structure of traditional rice noodles, and makes the prepared nutritional rice noodles for infants and young children richer and more comprehensive in nutrition. In addition, it is equipped with a nutrition package containing compound prebiotics and compound probiotics, which greatly enriches the nutrients in rice noodles, which can significantly improve the immunity of infants and young children, improve the gastrointestinal function of infants and young children, and reduce the risk of getting angry after eating , diarrhea and indigestion.

The invention discloses health tea and a preparation method thereof. The health tea is prepared from the following raw materials in parts by weight: 25-45 parts of rosa roxburghii tratt fruits, 20-40 parts of fructus cannabis, 25-45 parts of broadleaf holly leaf, 10-20 parts of pawpaw, 8-15 parts of emblic leafflower fruits, 5-10 parts of isatis root, 5-10 parts of gynostemma pentaphylla, 15-25 parts of radix astragali and 12-18 parts of the root of kudzu vine. By virtue of the preparation method, the health tea is prepared from the pure natural traditional Chinese medicinal materials and the broadleaf holly leaf; the tea tastes slightly bitter at the beginning and then sweet, is good in taste, and can be continuously brewed for 4-6 times; meanwhile, tests show that the health tea has a good effect of treating diabetes and obesity and also has a certain effect of relieving symptoms such as insomnia and dreamful sleep, hypertension, dyspepsia and the like.

The invention provides a children's traditional Chinese medicinal preparation for spleen and stomach reinforcing, qi rectifying and stagnation transforming. The preparation is a pure traditional Chinese medicinal preparation prepared by refining thirteen traditional Chinese medicines comprising ginseng, Rhizoma Atractylodis Macrocephalae, dried orange peel and the like through a modern technology. The preparation has the characteristics of reasonable composition, advanced technology, safety, no toxic side effects, and definite and reliable therapeutic effect. The preparation has the spleen and stomach reinforcing, qi rectifying, stagnation transforming and growth promoting functions, and is mainly used for treating spleen-stomach deficiency, emaciation with sallow complexion, spiritual drowsiness, anorexia, less meal, dyspepsia, inappetence, stomach swelling, children's infantile malnutrition and the like. The total effective rate of the preparation is 96.7%, wherein the cure rate is 16.5%, and the apparent rate is 65.1%. The preparation can promote the body weight increase, has no obvious influences on the breathing, the blood pressure or the heart rate of sick children, can rise the erythrocytes and hemoglobins of the sick children, and has no toxic side effects or untoward effects during the clinic observation period. The preparation has a definite therapeutic effect, has no toxic side effects, and is a good product for controlling children's spleen vacuity after infection, children's anorexia, children's easy infection children's blood deficiency and the like. The preparation has the advantages of good absorption, taking convenience, easy reception by the sick children and parents, and the like.