57 results about "Epidemic outbreak" patented technology

The invention provides a platform technology with rich ability to flexibly perform, create, deploy, maintain, and update a wide range of panels, assay, array, and/or sequence of tests for a wide range of substances and pathogens. The invention provides a unifying framework for widely-ranging miniature sensor implementation, fluidic/gas interfacing, electrical interfaces and optical interfaces, and further by collocating, allowing the integration a large number highly-selective sensors and chemical sensors—together as needed with appropriately selected supplemental sensors (for example temperature, pH, selective ions, etc.), into a common readily-manufacturable framework. The diverse sensor arrays give rise to statistical enhancing through novel statistical processing approaches. The invention is deployable and useable in a wide range of situations previously unavailable, and addresses many otherwise problematic aspects of field testing for food safety, water safety, epidemic outbreaks, routine diagnosis, and disease monitoring.

The present invention relates to a method for predicting outcome and evaluation of clusters. Particularly the invention relates to a method of determining deviation and predict future out comes of clusters with certain attributes. In one embodiment, the present invention relates to epidemic outbreaks of disease and, more particularly, to a method for predicting the spread thereof.

The invention discloses a precise management and control system for infectious epidemic situations. The system comprises an epidemic situation infection triggering mechanism, the system comprises a real-time positioning data packet data fuzzification processing technology, an epidemic situation infection intersection result elimination technology, a data group binding method, a data group removaljudgment method, a data combination analysis measure when multiple mobile phone user mobile phones are used at the same time, an epidemic situation prevention and control team and resource optimal configuration method and an epidemic situation prevention and control danger upgrading and degrading mechanism. According to the system and the method, at least basic data is collected, secrets behind the data are analyzed and deeply interpreted, infection tracing, epidemic outbreak prevention and diffusion early warning can be accurately carried out, epidemic prevention management and control personnel and epidemic prevention management and control resource materials are optimally distributed, accurate management and control are realized, and national economy and personal collective loss are reduced to a great extent.

The invention discloses a multivariate accurate management and control system for infectious epidemic situations. The multivariate accurate management and control system comprises a user client and adata analysis management and control terminal, wherein a user installs real-time locating information acquisition software; and the data analysis management and control terminal at least comprises a storage database module, a data analysis software module, a data interaction software module and an instruction sending confirmation module. The data analysis software module performs processing and calculation to capture key features and/or data intersection, so epidemic situation management and control data is obtained and guides epidemic prevention management ministries and commissions, cooperation department groups and mobile phone users to effectively prevent and treat infectious epidemic situations. According to the system, the least and the most fundamental data is collected, secrets behind the data are analyzed and deeply interpreted, infection tracing, epidemic outbreak prevention and early warning of spreading can be accurately carried out, epidemic prevention management and control personnel and epidemic prevention management and control resource materials are optimally distributed, accurate management and control are realized, and the loss of national economy, individuals and groups are reduced to a great extent.

The invention provides for a novel dynamically configurable point-of-care device for clinical diagnostics and research for analysis of activity associated with pluripotent stem cells, tumor cells, drug metabolites, immunological response, glucose monitoring, cardiovascular diseases, liver cell therapy, cell-cell signaling, epidemic outbreaks, hospital based infectious diseases, pathogens, germ cells, pharmacological compounds, oxidation reduction, microscopy, tomography, flow cytometry, clinical lab testing, and for providing immunoassays, ELISA, electrophoresis, PCR, chromatography, and other laboratory functions. The device comprises a biochemical processing module further comprising a processor and at least one controller, receiving microfluidic elements, sensors, software scripts, an electrically operated interface, flow ports, a user interface, memory, and a communications link, configurable based on analysis of patient data. The invention further provides for multiple-criteria decision analysis for hospital administrators, a wearable device, mobile medical device, molecular electronics configuration, touchscreen recognition, data analytics application, and a drone delivery based point-of-care system.

The invention discloses a precise management and control system for infectious epidemic situations. The precise management and control system comprises an epidemic situation judgment and control step,a real-time positioning data packet interpretation technology, a measure directed at the situation that a mobile phone user does not cope with an epidemic situation according to operation requirements prescribed in epidemic situation prevention and control measures, and treatment measures for early warning of the epidemic situations. According to the invention, historical instant speed vectors and accelerations of the user can be calculated, solved and drawn according to positioning displacement and time difference between real-time positioning information, so the moving tool and moving behavior of the user can be judged; and therefore, the system is of great significance to accurately analyze whether an infection place and an infection mechanism will continue to exist or not. According to the system, minimum basic data is collected and secrets behind the data are analyzed and deeply interpreted, so infection tracing, epidemic outbreak prevention and early warning of epidemic spreading can be accurately carried out, management and control personnel and resource materials for epidemic prevention are optimally distributed, and accurate management and control are realized.

The invention discloses a macrobrachium rosenbergii nodavirus detection kit and detection method. According to the detection kit, with the combination of the characteristics of isothermal amplification and rapid detection of nucleic acid test strips, expensive instrument equipment is not required during the detection process; and the color display is performed by utilizing the nucleic acid test strip, so that the detection reliability and the result judgment easiness are improved. The detection kit is low in detection cost and convenient to use and is safe for people and environment, and is capable of replacing the existing relevant detection methods. The detection kit can be used on wild production site and in laboratories in various levels, and has popularization and application value in the aspects of enhancing macrobrachium rosenbergii nodavirus detection, discovering and controlling the individual propagation of infected macrobrachium superbum infected by virus in real time, discovering and preventing the large-scale epidemic outbreak of the epidemix disease and the like.

The invention discloses an epidemic prevention and control oriented population dynamic contact structure modeling and discovery method. The method comprises the following content: a method for modeling a population dynamic contact structure by using a metapopulation based third-order tensor; a method for constructing a spatial mode of the population contact structure by using an analog simulation technology based on population statistics data; and a method for inferring a time mode of the population contact structure by using a data mining technology based on epidemic monitoring data. The invention provides a brand-new and efficient method for modeling and discovery of the population contact structure. Compared with an existing method, the method provided by the invention has the following advantages: (1) the population dynamic contact structure modeling and discovery method is provided, and the dynamic contact structure better conforms to a contact mode of human being; (2) the method can be applied to modeling and discovery of large-scale population contact structures; (3) the method has the characteristic of low cost; and (4) the obtained population dynamic contact structure can accurately predict epidemic outbreak and planning of epidemic prevention and control measures.

The invention discloses a kit and a detection method for detecting carbapenem-resistant enterobacteriaceae (CRE). The detection primer pair in the present invention is selected from one or several pairs of KPC detection primer pair, NDM detection primer pair, IMP detection primer pair, VIM detection primer pair and OXA-48 detection primer pair. The kit described in the present invention covers common carbapenem-resistant genes, with a minimum detection of 1 copy/uL. The detection method of the invention has the characteristics of good sensitivity, high specificity, accurate quantification, etc., and has important clinical significance for the detection and monitoring of the increasingly severe CRE epidemic outbreak.

The invention discloses an epidemic situation early warning and processing method, system and device and a storage medium. The method comprises the steps of putting feature data of viruses collected from all medical institutions into a virus feature model to be calculated to obtain a virus analysis result; giving an alarm in response to the fact that the similarity between the virus analysis result and the virus characteristics exceeds a threshold value; acquiring original data information of infected people and suspected infected people of viruses, and determining people with infection risksbased on the original data information; and determining the geographic position of the person at risk of infection, and notifying the manager closest to the geographic position. According to the epidemic situation early warning and processing method, system, device and the medium provided by the invention, viruses causing epidemic situations can be discovered in time before the epidemic situationsburst; at the beginning of epidemic outbreak, an epidemic outbreak source can be positioned in an extremely short time, suspected infected persons can be positioned in real time, and the negative influence of epidemic outbreak on daily life of people is minimized as much as possible.

The invention provides a pneumatic membrane structure virus detection lab and a casing soil virus detection lab. The pneumatic membrane structure virus detection lab comprises multiple pneumatic membrane structures; each pneumatic membrane structure can form a main space unit used as a main functional area and one or more sub space units used as auxiliary functional areas after being inflated; themain space units communicate with each other through the sub space units; a one-way air inlet is formed in the main space unit in each pneumatic membrane structure; a one-way ventilation port with afiltering device is formed in an internal opening and closing door in each pneumatic membrane structure; and one-way air outlets having filtering devices and used for the air to be exhausted are formed in the side surfaces, adjacent to the internal opening and closing doors, in the sub space units. According to the pneumatic membrane structure virus detection lab and the casing soil virus detection lab, as a pneumatic positive pressure structure is adopted, the building supporting structure is simplified and the whole closeness of the whole system is also guaranteed through combination of a positive pressure pneumatic membrane structure and a prefabricated construction system. Therefore, without foundation construction, the pneumatic membrane structure virus detection lab can be rapidly deployed; and the pneumatic membrane structure virus detection lab is especially beneficial for responding to emergency during epidemic outbreak and can be rapidly placed in needed places.

The invention discloses a safe long-acting antiviral antibacterial agent. The antiviral antibacterial agent comprises an organosilicon quaternary ammonium salt, nano-silver antibacterial powder and purified water, wherein a mass percent of the organosilicon quaternary ammonium salt is 4%, a mass percent of the nano-silver antibacterial powder is 0.6%, and a mass percent of the purified water is 95.4%. The invention discloses a safe and non-toxic spray dressing with long-acting antibacterial and antiviral functions; the safe long-acting antiviral antibacterial agent can pass various safety tests and can only be subjected to archive management as liquid dressings or spray dressings of class I medical appliances; the safe long-acting antiviral antibacterial agent can be used for disinfecting,sterilizing, killing acarids and removing off odors, can be used for stopping cutaneous pruritus and resisting bacterial and viral infections and is an invisible protective suit capable of resistingbacteria and viruses; and the safe long-acting antiviral antibacterial agent meets daily healthy and sanitary protection demands and anti-infection demands of shallow wounds and postoperative wounds and plays a huge role in controlling epidemic outbreaks and preventing propagation in case of great epidemic outbreaks.

The invention provides a double fluorescent quantitative RT-PCR (reverse transcription-polymerase chain reaction) kit for detecting dengue virus and zika virus. The kit comprises a quantitative RT-PCR reaction liquid, an enzyme mixed liquid, a primer probe mixed liquid, standard products (DENV and ZIKV), strong-positive reference products (DENV and ZIKV), weak-positive reference products (DENV and ZIKV), and negative reference products. The kit has the advantages that primer probes with high specificity for DENV and ZIKV are designed according to high conservancy of DENV and ZIKV and the polyprotein protein area with smaller difference between types; the dengue virus and the zika virus can be simultaneously detected through one-time reaction in a single tube by a single tube one-step type double real-time fluorescent quantitative RT-PCR; the specificity and sensitivity are high, and the kit can be used for the laboratory emergency diagnosis of epidemic outbreak caused by dengue virus and zika virus, quick screening, clinical diagnosis, and study of epidemiology of fever eruption virus.

The invention relates to a prawn covert mortality nodavirus (CMNV) fluorescent quantitative PCR (RT-PCR) detection method. The method includes the steps that a primer and a Taqman probe are designed according to a RNA polymerase gene conserved gene segment on which RNA of the CMNV depends, an RNA sample is prepared, and fluorescent quantitative RT-PCR is carried out according to preset reaction conditions. By means of standard curve manufacturing and specificity verification of the detection method, results show that absolute quantification of the CMNV can be achieved through the method. Meanwhile, the CMNV can be accurately identified from the white spot syndrome virus, the baculovirus, the taura syndrome virus, the hepatopancreatic parvovirus, the infectious hypodermal and hematopoietic necrosis virus and the infectious myonecrosis virus through the method, and high specificity is represented. The primer, the probe and the detection method have high popularization value in enhancement of monitoring of the CMNV in water, bait and offspring seeds and prevention of large-scale epidemic outbreak of the CMNV.

The present invention discloses a vehicle-mounted negative pressure gas collection and disinfection system. The system comprises a transfer trolley; the transfer trolley is provided with a stretcher and a chamber for placing the stretcher; the stretcher is provided with a gas collection hood; the gas collection hood is located above the head end of the stretcher; the gas collection hood is of a hollow structure; the inner wall of the gas collection hood is provided with gas holes; the gas collection hood is provided with a gas guide pipe communicating with the gas collection hood; a gas inletpipeline of the transfer trolley is provided with a branch pipe; and the tail end of the branch pipe extends into the chamber and can communicate with the gas guide pipe. The system is suitable for manual transfer of respiratory tract infectious disease patients, the infection of the public environment is reduced, the infection risk of transfer personnel along with the trolley is lowered, the mental stress is relieved, the structure is convenient and quick to mount, accessory materials are easy to obtain, and the system is particularly suitable for use in the epidemic outbreak period.

The invention provides a triplet fluorescence quantitative detection kit for PRRSV (Porcine reproductive and respiratory syndrome virus), HP-PRRSV (Highly pathogenic porcine reproductive and respiratory syndrome virus) and CSFV (Classical Swine Fever Virus). The triplet fluorescence quantitative detection kit comprises primers and probes listed in SEQ ID No.1-9 in a sequence table, as well as a total virus RNA extraction agent, an RT-QPCR mixed enzyme solution, RNase Free dH2O, and one or more of positive controls and negative controls. The kit is based on a triplet fluorescence quantitative PCR technology, PRRSV molecules, HP-PRRSV molecules and CSFV molecules are simultaneously detected, the kit is applied to detection of insignificant-content samples such as animal lungs, lymph glands, spleens, kidneys, hearts, livers, blood and meat products, whether the sample donors are contaminated or not is determined, and the kit is applicable to quarantine of live animals and meat products. The kit has the advantages of good specificity and high sensitivity, the detection cost is greatly lowered through joint detection, the detection time is saved, and the type of a pestilence can be conveniently determined in a short time at an epidemic outbreak.

The invention discloses a general purpose real-time fluorescent RT-PCR (reverse transcription-polymerase chain reaction) non-diagnostic method for Hantaan virus detection. The detection method comprises the following steps: selecting a Hantaan virus L gene full-length sequence, performing homologous alignment, and designing primers in a conserved region; designing a specific probe according to a nucleotide sequence in a PCR amplification region, and detecting the specificity of the probe; and performing real-time quantitative analysis on an object to be detected. The specific fluorescent probe is used to perform a completely closed pipe type operation, so that the possibility of polluting the amplification product is greatly reduced, and experiment steps, experiment time and the consumption of reagents are reduced. At present, no general purpose Hantaan virus detection method exists, and the existing method is basically used for singly amplifying one corresponding type based on one Hantaan genotype. According to the invention, the pair of primers and the probe are used to detect Hantaan viruses of different genotypes, the real-time PCR has very high sensitivity and specificity, and the detection of a Hantaan virus gene is sensitive and accurate. In practice, the method has a high application value especially in case of an epidemic outbreak.

The invention relates to the application field of biological detection technologies, and in particular relates to a primer pair and a kit for coxsackievirus A6 type RT-LAMP (Reverse Transcription Loop-mediated Isothermal Amplification) nucleic acid detection. The primer pair comprises two outer primers F3 and B3, two inner primers FIP and BIP and two loop primers LF and LB; and the kit comprises the primer pair. The CA6RT-LAMP has the characteristics of strong specificity, high sensitivity, simplicity in operation methods, quick detection, easiness in result judgment, low cost and the like, can better satisfy the requirement of on-site quick detection, is easy to popularize and apply in grassroots units, can be used for early rapid diagnosis of epidemic outbreaks, such as hand-foot-and-mouth diseases and the like and clinical cases in disease prevention and control organizations, hospitals, kindergarten units, and has broad market prospect and enormous economic and social benefits.

The invention belongs to the technical field of medical facilities, and particularly relates to an isolation negative pressure shelter for infectious disease prevention and control. The isolation negative pressure shelter comprises a base and a cover plate group, wherein a wall body group is mounted between the base and the cover plate group, the wall body group comprises a fixed wall, a movable wall and two foldable side wall groups, a door frame is arranged on the fixed wall, and a sealing door is mounted in the door frame. The base comprises two underframe groups and a plurality of supporting plates detachably mounted between the two underframe groups, each side wall group comprises a plurality of side wall plates which are hinged in sequence, the fixed wall and the movable wall are parallel to each other, a first fixing structure is arranged between the side wall plates and the underframe groups, and the cover plate group comprises a first cover plate, a second cover plate and a plurality of third cover plates. The third cover plates are sequentially connected between the first cover plate and the second cover plate, and a second fixing structure is arranged between the cover plate group and the wall body group. The negative pressure shelter aims to solve the problems that due to the structural defects of an existing negative pressure shelter, assembling is complex, the construction time is long, and the rapid construction requirements during epidemic outbreak are difficult to meet.

The invention provides a composite sterilizing agent, and relates to the field of sterilizing liquid. The composite sterilizing agent is characterized in that flavoring agents are added; in the use process, fresh and elegant mint flavor is realized; the sterilizing agent is suitable for being used for skin and air sterilization; the sensory happiness of people can be improved. In addition, the sterilizing agent contains various sterilization ingredients; the goal of fast and efficient killing can be achieved in epidemic outbreak places or during flu spreading. The sterilizing agent also contains metal corrosion inhibitors; the inhibition effects can be achieved on the corrosion on the surface of metal objects; the substitute use can be realized for occasions in which some chlorine-containing disinfectants cannot be used due to corrosion; the sterilization effect and the sterilization time are both superior to the chlorine-containing disinfectants.

The invention provides a BERT-based new coronal pneumonia epidemic situation microblog sentiment analysis method, equipment and a medium. The method comprises the following steps: acquiring microblog public opinion information and epidemic situation data related to a new coronal pneumonia epidemic situation; preprocessing the microblog public opinion information to obtain microblog public opinion data; performing sentiment analysis on the microblog public opinion data through a language model to obtain a sentiment analysis result; and processing the sentiment analysis result according to the microblog public opinion information and the epidemic situation data to obtain correlation analysis of the new coronal pneumonia epidemic situation. According to the method, a set of sentiment analysis model integrating data crawling, cleaning, storage, analysis and visualization is constructed, epidemic situation data and microblog public opinion data are integrated, model hyper-parameters are adjusted on a data set, the model accuracy is improved, finally, mainland epidemic situation development conditions are summarized and analyzed stage by stage, the correlation between the new coronal pneumonia epidemic outbreak situation and the public opinion emotion change is obtained, and the method has important significance on public opinion monitoring and obtaining in the epidemic period.

The embodiment of the invention provides an infectious disease checkpoint checking and control method. The method comprises the following steps: presetting a plurality of checkpoints, setting at leastone check gate at each checkpoint, and collecting personnel information of people to pass at the check gate; and judging whether the people to pass meet passing conditions or not according to the collected personnel information, generating certificates uniquely corresponding to the people to pass, and identifying the people to pass holding the certificates, so that the people to pass can pass through the check gate or a potential risk person isolation measure is enabled. In this way, the personnel information can be collected at the check gate at each checkpoint, and potential risk personnelcan be screened and differentially admitted and the like, so that the risks of epidemic outbreak and the like in a region due to the fact that infectious diseases are imported into a population-intensive region are reduced, the prevention and control efficiency is improved, the risk of infection of monitoring personnel is reduced, and the joint defense and joint control efficiency is improved.

The invention provides a Puer tea immune adjuvant. The adjuvant is characterized by consisting of the following components in percentage by mass: 0.05 to 100 percent of Puer tea extract and 0 to 99.95 percent of a carrier. The influenza vaccine adjuvant prepared from the Puer tea extract has good effectiveness, can improve the immunogenicity of antigens and enhance the immune effect, and solves numerous problems that the conventional immune adjuvant is single, the side effect is difficult to avoid, production and supply of vaccines are limited, the requirement for urgently providing a large quantity of vaccines in epidemic outbreak is difficult to meet, the response time of the vaccines is long and the like; and the quality of the vaccines is easy to control. A preparation method for the Puer tea extract is simple, convenient, wide in material source, economic and environment-friendly.