The invention provides a layer mixing method and device based on an open graphics library (OpenGL) and is applied to the technical field of images. According to the method and the device, a main interface view layer is established through a 3D application interface of an Android system and initialized; graphic drawing is performed in an area, which corresponds to a television (TV) frame, of the main interface view layer according to the size of the TV frame of a rear video layer of the main interface view layer, the area of the main interface view layer, which corresponds to the TV frame, is set to be transparent, when item superposition in the TV frame of the video layer is required, items to be superposed are drawn in the main interface view layer, and an area, where the superposed items are drawn, of the main interface view layer is set to be opaque. According to the layer mixing method and device based on the OpenGL, the superposed items in the TV frame are established on the main interface view layer so that superposition and mixing of multiple view layers are not required, and the controlling is further easy.