2 results about "Phosphate loading" patented technology

The present disclosure relates to a pharmaceutical composition for providing phosphorus to an adult or pediatric patient, wherein the composition is an aqueous solution of sodium glycerophosphate which by virtue of an improved process for producing the active pharmaceutical ingredient and the pharmaceutical composition is characterized by a low amount of free phosphate, a low amount of SGP-related substances and by a low amount of aluminum. The pharmaceutical composition is used in clinical nutrition, preferably in the preparation of nutritional formulations by compounding. The compositions can further be used for preventing or correcting phosphorus deficiency (hyperphosphatemia) in said adult or pediatric patients.

The application relates to the technical field of chemical analysis, in particular to a spectrophotometric determination method for phosphates in phosphorous acid, which comprises the following steps: adding a reducing agent to a sample to be measured to start a color reaction, synchronously triggering and performing double-wavelength high-frequency sampling, obtaining color light absorbance and background light absorbance at each moment during the whole determination process after the reaction is started; performing smoothing processing on the color light absorbance, evaluating the change degree of the smoothed color light absorbance with time to represent the time sequence characteristics of the change of the reaction rate, obtaining the relative change rate at each moment, and identifying the observation end moment when the main color reaction ends and the matrix interference drift starts; determining the interference drift rate, combining the reaction time, and determining the cumulative interference absorbance representing the matrix interference drift; obtaining the net absorbance, and determining the phosphate content in the sample to be measured. The application significantly improves the accuracy of the determination of trace phosphates in phosphorous acid.