14 results about "Silyamandin" patented technology

The invention provides a composition for improving the thrombolysis capacity of a human body, a preparation method and application thereof.The composition is prepared from, by weight, 5-30 parts of earthworm protein, 30-120 parts of hippophae rhamnoides total flavone extract, 50-150 parts of silymarin extract, 20-80 parts of maltodextrin and 15-60 parts of pregelatinized starch, the earthworm protein activates a fibrinolytic system to promote t-PA to release and dissolve thrombus, and the hippophae rhamnoides total flavone extract activates the fibrinolytic system to promote t-PA to release and dissolve thrombus; the hippophae rhamnoides total flavonoids regulate the ratio of PGI2 / TXA2 to inhibit platelet aggregation and reduce blood fat, the silymarin protects the liver function to enhance LDL-C metabolism clearing, the hippophae rhamnoides total flavonoids, the silymarin and the hippophae rhamnoides total flavonoids cooperate to form a thrombolysis-antithrombosis-metabolism regulation three-dimensional intervention system, a whole-course low-temperature mixing direct tabletting process is adopted

The application discloses a culture method for enhancing the body color of Eaststar Prawn and relates to the technical field of aquaculture. The method comprises the following steps: (1) light induction: white-red-blue-yellow light sources are alternately used for irradiation, (2) color enhancer feeding: the color enhancer is fed simultaneously with the basic feed, and the components of the color enhancer include Camellia nitidissima polysaccharide, Sargassum fusiforme polysaccharide, fucoxanthin, scallop peptide, silymarin, guanidino acetic acid and sodium butyrate, and (3) water flow stimulation. Through the regulation of physiological metabolism, nutrient absorption and environmental adaptability, the method jointly acts on the body color performance of Eaststar Prawn, is favorable for enhancing the body color of Eaststar Prawn and improving the economic value of Eaststar Prawn.

Cosmetic and dietary supplement compositions containing silymarin and sulfoalkyl ether cyclodextrin, particularly sulfobutyl ether cyclodextrin, are described. The compositions and methods are useful in reducing appearance of facial redness in rosacea-prone skin, rejuvenating skin, preventing skin aging, inhibiting oxidative stress in epidermal and dermal cells, increasing collagen production, reducing the likelihood of skin cancer, treating or reducing liver damage from a toxin, or treating a liver disease.

The invention relates to a novel formulation or composition of krill oil and silymarin and use thereof, in particular for the treatment and prophylaxis of liver diseases.

The invention belongs to the field of natural pharmaceutical chemistry and the field of cosmetics, and particularly relates to a skin care composition, a skin care product and application thereof.The skin care composition comprises silymarin, epigallocatechin gallate and quercetin, and the mass ratio of the silymarin to the epigallocatechin gallate to the quercetin is (3-7): (3-10): (1-5). The skin care product comprises the skin care composition, the content of the skin care composition is 0.5-10%, the skin care composition or the skin care product is applied to preparation of the skin care cosmetics, the esterified lecithin is used for encapsulating the silymarin, the epigallocatechin gallate and the quercetin, and sodium hyaluronate is matched, so that the skin care composition or the skin care product can be used for preparing the skin care cosmetics. The problems that flavonoid compounds are difficult to dissolve, permeate and absorb are effectively solved, and meanwhile, the skin care composition and sodium hyaluronate have a synergistic effect, so that the moisturizing, wrinkle removing and aging resisting effects are remarkably improved.

Nutritional supplements and compositions for activating cellular signaling genes in innate inflammatory pathways are described in this application. In particular, this application describes a composition containing a solid portion comprising Bacopa monnieri extract having a least 20 percent bacosides, Silybum marianum (milk thistle) extract having 70 percent to about 80 percent silymarin, milk thistle extract, Withania somnifera (ashwagandha) extract, Camellia sinensis (green tea) extract containing at least 40 percent epigallocatechin gallate and about 98 percent polyphenols; and Curcuma longa (turmeric) extract containing at least about 95 percent curcumin. The compositions also comprise a liquid portion comprising fish collagen peptides comprising about 90 percent protein and Formosa ruby quinoa water extract containing about 10 wt % extract and about 90 wt % water. These compositions improved the skin and impacted key regulatory genes associated with several important cellular pathways. Other embodiments are also described.

The invention discloses a composition for protecting liver functions and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The preparation method comprises the following steps: firstly, treating chrysanthemum in steps, preparing part of chrysanthemum into sterilized fine powder for later use, and adding part of chrysanthemum into an extraction system; the preparation method comprises the following steps: crushing and breaking shells of part of cassia seed and cistanche, mixing with Chinese angelica, performing ethanol percolation extraction, performing secondary water reflux extraction on decoction dregs and other traditional Chinese medicine raw materials, combining percolate and reflux filtrate, and concentrating; synchronously preparing a silybum marianum extract, a Chinese magnoliavine fruit extract and reduced glutathione which meet standards, spray-drying a concentrated solution, adding the chrysanthemum fine powder and the three types of core extracts, and performing three-dimensional mixing to obtain a finished product. The silymarin is used for enhancing liver cell membrane protection, the schisandra chinensis extract is used for activating an endogenous antioxidant system, the reduced glutathione is used for removing toxic substances, the traditional Chinese medicine components are used for synergistic interaction, meanwhile, the process is optimized to guarantee uniform component retention and distribution, and the problems that a traditional preparation is single in effect and unstable in quality are solved.

Provided is a method for improving or regulating liver metabolism level, enhancing or maintaining liver function, improving or maintaining liver health in a subject, which includes administering to the subject an effective amount of tetrahydrocurcumin and silymarin composition. The composition can be widely applied to nutritional supplements, foods and beverages.

The application aims to establish a solubilization system for improving the dissolution of silymarin and prepare silymarin-loaded polymer microspheres, and belongs to the technical field of pharmaceutical preparations. The silymarin polymer microspheres prepared by the solubilization system can significantly improve the dissolution of silymarin. The method for preparing the silymarin polymer microspheres in the application is as follows: S1: uniformly mixing pre-activated corn starch, nicotinamide and O / W emulsifier in deionized water to form an aqueous phase; S2: dissolving silymarin in ethyl acetate to form an oil phase; S3: slowly adding the oil phase to the aqueous phase and stirring at high speed to prepare an emulsion; S4: placing the emulsion in an ice water bath for several hours, centrifuging, taking the precipitate, and freeze-drying to obtain silymarin microspheres.

This invention belongs to the field of feed additives, and particularly relates to a montmorillonite-co-loaded silymarin nanosuspension and its preparation method. The montmorillonite-co-loaded silymarin nanosuspension comprises montmorillonite, silymarin, liquid phospholipids, and chitosan, wherein silymarin is loaded onto the surface and interlayer of montmorillonite via liquid phospholipids, forming a nano-dispersion system with a particle size distribution of 150–320 nm. The montmorillonite-co-loaded silymarin nanosuspension and its preparation method provided by this invention achieve efficient loading, nano-dispersion, and liver-targeted delivery of silymarin.

The invention relates to the technical field of cosmetics, in particular to a silymarin composition, a transparent aqueous solution and a preparation method of the transparent aqueous solution, the silymarin composition at least comprises silymarin, nicotinamide, hydrophilic polyol and water, and the mass ratio of the silymarin to the nicotinamide to the hydrophilic polyol to the water is 0.05: (2-3): (2.5-5): 2. By optimizing a composition formula system, the dissolution of the silymarin in water is realized, and the silymarin can be stabilized in a transparent aqueous solution product system without additionally adding a specific emulsifier, a solubilizer and the like subsequently, so that the application range of the silymarin is expanded.

The invention belongs to the technical field of medicines, and particularly relates to a silybum marianum composition for improving liver function and a preparation method thereof, the composition comprises quick-release cholagogic micro powder and slow-release liver-nourishing particles in a mass ratio of 1: (2-4); the quick-release cholagogic micro powder is prepared from curcumin, fructus aurantii immaturus flavone, a tanshinone extract and PVP K30 through ball-milling solid dispersion; the slow-release liver-nourishing particle is of a core-shell structure, a freeze-drying core of the slow-release liver-nourishing particle contains silymarin and schizandrin extract, and a glycyrrhetinic acid-phospholipid / chitosan oligosaccharide targeted coating and a medicinal acrylic resin coating are sequentially arranged on an outer layer of the slow-release liver-nourishing particle. According to the composition, through sequential synergy of'first defibering and then repairing 'and a liver targeting effect, the content of silymarin in liver tissue is remarkably increased, the silymarin is retained for a long time, and liver function impairment such as non-alcoholic fatty liver disease is effectively improved.

The present application relates to the field of medical devices, the field of medical or toiletry formulations, the field of biopharmaceutical manufacturing technology and the field of formulation manufacturing technology, in particular to a supramolecular anti-aging composition suitable for sensitive skin population and a preparation method and application thereof. Active ingredients, inclusion materials, emulsifiers and solvents; the active ingredients include: silymarin, silatrane and phytol; the silymarin includes silybin, silychristin and silydianin; the inclusion material includes at least one of hydroxypropyl-alpha-cyclodextrin and hydroxypropyl-beta-cyclodextrin; the emulsifier includes at least one of oleyl polyether-20, Tween 80 and PPG-13-decyltetradecyl alcohol polyether-24; the solvent includes water and polyhydric alcohol. The composition provided by the present application has excellent anti-aging efficacy and stability, and has good effect of reducing allergy, and is suitable for sensitive population.

The present invention discloses a natural plant liver-protecting formulation based on promoting bile secretion and a preparation thereof, relating to the technical field of natural plant medicine and health food. The present invention effectively achieves a liver-protecting effect through multi-target synergistic actions of promoting bile secretion, cholagogic and detoxifying effects, and directly protecting liver cells. Among these, the milk thistle extract is rich in silymarin, which can stabilize hepatocyte membranes, prevent toxic substances from entering hepatocytes, and promote the repair and regeneration of damaged hepatocytes. Cynarin in the artichoke extract promotes bile secretion, accelerates the excretion of toxins and waste from the body, and reduces the burden on the liver. The total flavonoids component in the dandelion root extract has anti-inflammatory and antioxidant effects, which can protect hepatocytes from free radical damage, thereby comprehensively improving liver health.