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6 results about "Taste Bud Cells" patented technology

Taste buds contain the taste receptor cells, which are also known as gustatory cells. The taste receptors are located around the small structures known as papillae found on the upper surface of the tongue, soft palate, upper esophagus, the cheek and epiglottis.

Treatment of Memory Loss with Phosphodiesterase Inhibitors

PendingUS20260041690A1Nervous disorderBoron compound active ingredientsPhosphodiesterase inhibitorSmell loss
Smell loss (hyposmia) is a common cognitive deficit perceived clinically as a nasal abnormality but, in reality, it is a deficit of complex biochemical detection and processing of externally generated chemical events. A major mechanism initiating hyposmia involves abnormalities of growth of human olfactory cells through altered growth factor stimulation of stem cell activity. While several growth factors are involved well known signaling substances generate and perpetuate this process; among these substances are cAMP and cGMP. We have hypothesized a role for cAMP in taste and olfaction as a growth factor necessary for stem cell maturation. We have thus measured cAMP and cGMP in parotid saliva of 19 normal subjects and 144 patients with hyposmia to evaluate roles for these signals in cognition. Results indicate that patients secrete significantly less cAMP (0.40+ / −0.03 pmol / mg protein (Mean+ / −SEM); patients; 0.67+ / −0.09, normals, p<0.005) and significantly less cGMP (0.072+ / −0.003, patients; 0.100+ / −0.007, normals, p<0.005) than do normals. While parotid gland secretions relate directly to taste bud growth factors many substances secreted in saliva are similar to those secreted in nasal mucus. The present results indicate aberrant signaling in saliva may serve both as a marker for hyposmia and as an indicator of a mechanism which interferes with olfactory system function.
Owner:CYRANO THERAPEUTICS INC

Oral structure for relieving pain and quenching thirst after general anesthesia

The invention relates to the technical field of rehabilitation medical instruments, in particular to a pain relieving and thirst quenching buccal structure used after general anesthesia. Comprising a base, a supporting module, a shell, a controller, a cable, a fixing base, a supporting frame, a refrigeration piece, a temperature conduction rod, a mouthpiece, a cooling head, a rail, a sliding block and an adjusting module, the controller is arranged in the shell, the two ends of the cable are connected with the controller and the refrigeration piece correspondingly, the supporting frame is slidably arranged in a containing groove, and the refrigeration piece is fixedly connected with the supporting frame; the two ends of the temperature conduction rod are connected with the refrigeration piece and the mouthpiece respectively, the cooling head is fixedly connected with the mouthpiece, the rail is fixedly connected with the fixing base, the sliding block is fixedly connected with the supporting frame and located on the outer side wall of the supporting frame, the sliding block is arranged in the rail in a sliding mode, and the adjusting module is connected with the supporting frame. The effects of being convenient for operation patients with different tooth conditions to use after the general anesthesia operation and being beneficial to stimulating taste buds of the operation patients to secrete saliva are achieved.
Owner:核工业四一六医院

A method for enhancing the sweetness of cigarette smoke based on aroma synergy

PendingCN122096458ATobacco preparationTobacco treatmentBiotechnologySmell Perception
The application discloses a cigarette smoke sweet feeling enhancement method based on aroma synergy, which comprises the following steps: preparing a sweet feeling enhancement base: dissolving or dispersing an aroma composition composed of milk flavor, caramel sweet flavor and fruit sweet flavor in a solvent to form a sweet feeling enhancement base; applying the sweet feeling enhancement base: applying the prepared sweet feeling enhancement base to cigarette material to obtain cigarette material treated by the sweet feeling enhancement base; subsequent treatment: balancing the cigarette material treated by the sweet feeling enhancement base and rolling the cigarette material into cigarettes. The cigarette smoke sweet feeling enhancement method based on aroma synergy does not directly act on taste buds, but adds specific aroma combinations that can effectively induce and enhance sweet feeling perception, utilizes the cross-modal interaction of olfaction-taste, and forms a stronger and more natural sweet feeling experience in the brain of consumers; the method does not directly stimulate taste buds, and fundamentally avoids the after-bitterness and metallic taste possibly caused by excessive sweeteners.
Owner:CHINA TOBACCO HENAN IND CO LTD

Adjustable bionic tongue sleeve type straw

ActiveCN224140549Uavoid mixingImprove the taste of drinking waterTablewaresTongue surfaceSilica gel
The utility model provides an adjustable bionic tongue sleeve type suction tube, which belongs to the technical field of suction tubes and comprises a bionic tongue sleeve. Comprising a silica gel base body, a plurality of main flow channels formed in the upper layer of the tongue face part of the silica gel base body, a main flow dividing groove formed in the silica gel base body and communicated with the confluence ends of the main flow channels, a flow dividing cavity formed in the lower layer of the tongue face part of the silica gel base body, and a plurality of auxiliary flow dividing grooves formed in the bottom of an inner cavity of the flow dividing cavity. The main channel and the auxiliary channel operate independently, the taste bud area is covered in a directional mode through the micro-flow through holes of the auxiliary channel, the main channel avoids the sensitive area, liquid mixing is effectively prevented, meanwhile, the drinking taste is improved through trace flavor liquid, and the drinking desire is stimulated; by means of the more than eight main flow channels distributed in the radial shape and the detachable channel plugs, a user can freely block part of the channels, the liquid flowing path and flow distribution are dynamically changed, and the comfort experience of the user can be improved.
Owner:博兴成蹊科技工作室(个人独资)

Traditional Chinese medicine composition for treating children eczema

The invention relates to the technical field of traditional Chinese medicine compositions for children eczema, and discloses a traditional Chinese medicine composition for treating children eczema, which comprises 4-10 parts of cape jasmine flower, 6-11 parts of turmeric, 4-9 parts of borneol, 4-14 parts of alum, 15-30 parts of dark plum, 7-14 parts of red sage root, 8-20 parts of purslane, 4-9 parts of purified water and 3-6 parts of glycerin. The preparation method of the traditional Chinese medicine composition comprises the following steps: step 1, simultaneously putting the same amount of gardenia, turmeric, borneol, alum, dark plum, salvia miltiorrhiza and purslane into crushing equipment, mixing and crushing; according to the traditional Chinese medicine composition for treating children eczema, through the brand-new prepared traditional Chinese medicine composition, the traditional Chinese medicine composition is more excellent in infant eczema treatment, taste bud stimulation and oral administration harm are avoided, and the problems that existing medicines used for treating children eczema are large in taste irritation, are not suitable for infants when being orally taken, and are not suitable for children are solved. Therefore, the infant eczema treatment is influenced.
Owner:NANJING XINWEIFANG MEDICAL TECH CO LTD

A slow-release edible salt and a method for preparing the same

ActiveCN117297067BReduce release areaslow release rateLipidic food ingredientsFood shapingBiotechnologySalty taste
The application provides a slow-release edible salt and a preparation method thereof, and the slow-release edible salt comprises salt particles and a slow-release layer wrapped on the surface of the salt particles; the slow-release layer is prepared from the following raw materials in parts by weight: 100 parts of water, 3-10 parts of an emulsifier, 0.5-3 parts of sodium citrate, 4-10 parts of glutamine peptide, 0.5-1.0 parts of water-soluble soybean polysaccharide and 0.01-0.05 parts of tea polyphenol; the slow-release edible salt provided by the application is wrapped with a slow-release layer on the surface of the salt particles, so that the release area of the salt is reduced, the release speed of the salt is reduced, the release of the salt is retarded, and the slow-release effect of the salt is ensured; meanwhile, the glutamine peptide in the slow-release edible salt provided by the application can enhance the perception of salty taste by human taste buds, so that the intake of the edible salt is reduced.
Owner:YIYANTANG YINGCHENG HEALTH SALT MFG