48 results about "Taste Bud Cells" patented technology

The Split Can for Beverages is an advancement of the 12 ounce (oz.) beverage can having increased measurements throughout the entire can to satisfy primary improvements (additions) made to: (a) the top of the can and, (b) the interior center of the can. The Split Can for Beverages obtains on its top two smaller pull tabs positioned back to back (mirror images) as a thin piece (layer) of aluminum placed vertically in it's interior center forming a split. The Split Can for Beverages is a single aluminum can able to contain beverage products in a double embodiment having two sides (left and right) that are independent of each other functioning as two self-ruling usable single cans. In addition, because the Split Can for Beverages has two independent sides with their own set of opening mechanisms (pull tab, aluminum flap and opening) it maintains two different products comfortably, their brand names and designs. Whichever two different soft drink combinations or two different hard drink combinations, the Split Can for Beverages is able to be utilized while consumers maximize their taste buds by having two of their favorite drinks in one beverage can.

The invention relates to ivermectin effervescent granules for poultries. The ivermectin effervescent granules for poultries disclosed by the invention are composed of the following raw materials in parts by weight: 30-90 parts of ivermectin, 50-80 parts of citric acid, 60-90 parts of sodium bicarbonate, 30-60 parts of polyethylene glycol 6000, 60-90 parts of dextrin, and 80-200 parts of glucose. The ivermectin effervescent granules for poultries disclosed by the invention are prepared by crushing the above raw materials, mixing, granulating, drying and straightening. Different from common granules, the ivermectin effervescent granules for poultries disclosed by the invention contain an effervescent disintegrant; when the effervescent granules are put into drinking water, a large number of bubbles can be generated instantly under the action of the effervescent disintegrant, so that the granules are disintegrated and molten rapidly; therefore, taste buds of animals are stimulated; the release and action time of medicines are increased; furthermore, reagents adopted are conventional medicines, and thus, the ivermectin effervescent granules for poultries disclosed by the invention are low in preparation cost and easy to popularize and apply.

The present invention relates to high-throughput mammalian and medium-throughput oocyte-based electrophysiological assays for identifying human TRPML3 modulators, preferably TRPML3 enhancers. Compounds that modulate TRPML3 function in the assay are expected to affect salty taste in humans. The inventive electrophysiological assays, such as the two-electrode voltage-clamp technique, facilitate the identification of compounds which specifically modulate human TRPML3. The assays of the invention provide a robust screen useful to detect compounds that facilitate (enhance) or inhibit TRPML3 function. Compounds that enhance or block TRPML3 channel activity should thereby modulate salty taste. In addition, these compounds may be used to regulate sodium excretion, urinary output and other biological functions relating to sodium levels. This invention relates to the elucidation that TRPML3 is involved in salty taste perception in primates including humans and likely other mammals (given the significance of sodium and other ions to physiological functions and conditions this phenotype is likely strongly conserved in different animals). The TRPML3 gene also modulates one or more of sodium metabolism, sodium excretion, blood pressure, fluid retention, cardiac function and urinary functions such as urine production and excretion. The inventors have identified TRPML3 as encoding a salty taste receptor in primates and humans (and likely other mammals) based on gene expression assays which have determined that TRPML3 is expressed specifically in taste bud cells and not in lingual epithelial cells, similar assays that have determined that TRPML3 is specifically expressed or enriched in the top half of taste bud cells in a subset of taste cells which do not express TRPM5 or PKD2L1, prior reports that document the expression of TRPML3 in other sensory organs such as the ear (therefore further substantiating the role of TRPML3 as a 'professional' sensory gene).

The current invention relates to a gargle dosage formulation and a method for removing the bitter taste in oral medication or food. Particularly, this bitter-removal formulation comprises at least one of two preparations, the first preparation and the second preparation. The current invention also discloses a method of using the preparations before and after taking oral medication or food. Right before taking oral medication or food, the first preparation is used to gargle the user's oral cavity. After it is spat out, the first preparation forms a thin layer on the surface of the oral mucosa to cover, shield, and protect taste buds from the direct contact with oral medication or food. Immediately after oral medication or food is taken, the second preparation is used to gargle and clean the user's taste buds, which effectively elutes mucosa-binding bitter ingredients from the oral cavity. Because both preparations are spat out, there is neither body intake of these preparations nor interference to the oral medication. The gargle preparation can be generally used with various types of oral medication. Both preparations in this formulation are simple, safe, inexpensive, and easy to use. The first and second preparations may be used together or only one of them is used. The gargle preparation is very effective to minimize and remove tastes such as the bitter taste, peculiar taste, and dulled taste, which are associated with the traditional herbal medicine such as traditional Chinese herbs and their decoctions. The gargle preparation helps patients who are taking oral medication with the bitter taste to maintain healthy taste buds and improve life quality.

The invention discloses a drug taste-masking agent which is characterized by comprising the following components in parts by weight: 1-30 parts of pericarpium zanthoxyli, 0-30 parts of pepper, and 0-30 parts of chili, wherein the effective ingredients in the components are water extracts or alcohol extracts. The taste-masking agent which has the local anesthesia function can temporarily palsy taste bud cells and improve the bitter taste threshold value, thereby achieving the taste masking purpose. The method can also be applicable to the taste-masking of other antibiotics, thereby having a higher application value.

The invention discloses a preparation method for oral instant granules. Each oral instant granule is prepared from an outer enveloping capsule and built-in instant granules, the outer side of the outer enveloping capsule is coated with a sugar coating, the outer enveloping capsule is prepared from edible gelatin and pectin, and the built-in instant granules include a carrier aggregate and a drug factor. According to the method, the drug factor is carried by the carrier aggregate, so that a drug is distributed uniformly, the drug taste and bitter taste can be effectively covered, the granules have a popping candy effect after being eaten, the taste and flavor are unique and interesting, and the dissolution of the granules is further accelerated; the outer enveloping capsule is loaded with the built-in instant granules, so that the storage and moisture resistance of the granules are facilitated; and the sugar coating is wrapped around the outer side of the outer enveloping capsule to improve the sealing of the drug factor, an antioxidant is also used to maintain the drug effect of the drug factor, at the same time, the sugar coating is prepared from alpha-hydroxy acid to stimulate the taste bud and increase saliva, and the granules are released to moisturize and be adhered to the drug factor, so that the hidden danger of the granules entering trachea is reduced, and drug absorption is promoted.

A film composition for orally delivering a variety of substances to a person. In one embodiment, the substance is a reduced calorie sugar substitute derived from species of the plant genus Synsepalum. The reduced calorie substitute can be utilized to control calorie intake or to make the delivery of drugs, pharmaceuticals or cosmetics more palatable. In other embodiments, the substance is a drug product or medicant. Further, the film compositions can be used to deliver a wide variety of substances directly to the taste buds, thereby increasing the localized concentration of the substances. Also provided a generally applicable orally consumable sugar substitute.

The invention discloses a formula and a preparation method of electronic cigarette tobacco tar. The formula comprises essence and a tobacco tar base, wherein the tobacco tar base comprises a solvent and a greasiness reducing combination agent, wherein the solvent comprises glycerol, propylene glycol and water, the greasiness reducing combination agent comprises nicotine, organic acid and tobacco polyphenol, the weight percentage of nicotine in the tobacco tar base is 2-5%, the molar ratio of organic acid to nicotine is (1-3):1, and the weight percentage of tobacco polyphenol in the electronic cigarette tobacco tar is 0.0001-1%. According to the electronic cigarette tobacco tar disclosed by the invention, the greasiness reducing combination agent is added into the solvent, and comprises tobacco polyphenol, so that the tobacco polyphenol and derivative products thereof entering the oral cavity of a consumer can generate a relatively strong effect with taste buds when the consumer smokes, the perception of the consumer on the sweet greasy feeling is reduced, and the sweet greasy feeling of the tobacco-flavored atomized electronic cigarette is improved.

The invention provides a taste-masking compound based on a porous carrier and a preparation method and application thereof. The taste-masking compound consists of a soluble bitter drug, the porous carrier and a release regulator. According to the compound, the release of drugs from the taste-masking compound can be regulated and controlled, and the contact opportunity of the bitter medicine and taste buds in an oral environment is obviously reduced, so that the taste masking purpose is realized. The invention provides a prescription composition and the preparation method of the taste-masking compound. The taste-masking compound is suitable for taste masking of high-dose bitter drugs, drug release can be regulated and controlled according to needs, the taste-masking compound can be further prepared into granules, dry suspensions, orally disintegrating tablets, dispersible tablets, chewable tablets and other dosage forms suitable for children, the medication compliance of the children can be improved, and the clinical medication requirements of pediatric patients are met.

The present invention relates to a multifunctional pet food and a preparation method thereof. The multifunctional pet food can provide eight nutrient substances required by brain development, improvesmental activity of dogs, and has effects of benefiting brain and helping memory. By supplementing elements with stress reaction resistance and oxidation resistance, the multifunctional pet food effectively reduces damages of stress reaction on pets, plays effects of calming nerves and relieving tension emotions, can promote rapid proliferation of taste bud cells of tongue mucosa, regulates appetite, inhibits certain harmful bacteria in intestinal tracts, improves secretion functions of a digestive system and activity of enzymes in histiocytes, and finally plays effects in regulating intestines and stomach to help digestion. In conclusion, under synergistic effects of the raw materials, the multifunctional pet food has multiple effects of delaying memory decline, enhancing learning ability, relieving and relaxing stress reaction resistance, refreshing breath, improving intestinal health, protecting joints, helping sports, promoting development of puppies, etc.

According to the lacosamide oral solution and the preparation method thereof, sodium carboxymethyl cellulose, povidone and polyethylene glycol are used as taste-masking combined matrixes, the viscosity of the oral solution is increased, the contact time of a medicine and a taste bud is shortened, the strong bitter taste of the lacosamide oral solution can be effectively masked under the condition that a sweetening agent is not added, and the taste of the lacosamide oral solution is improved. The attention of a patient on bitter taste is transferred through the cooling effect of menthol, the medication compliance of the patient is improved, the stability of an oral solution is improved, and the validity period of the medicine is prolonged. In the lacosamide oral solution provided by the invention, the variety of auxiliary materials is less, the preparation method is simple, and the lacosamide oral solution has a good taste masking effect and stability.

The invention provides a sweet-milk-fragrance type flavoring agent for a feed used for sucking pigs and a preparation process thereof. The preparation process comprises the following steps: with natural cream as a main material and lipase, spice, ethyl lactate and the like as accessory materials, compounding the raw materials so as to separately obtain a mixture I, a mixture II, a fine mixture and fermentation broth, wherein every raw material is allowed to fully react with its corresponding ingredient and prevented from conflict with accessory materials conflicting with the raw material so as to prevent influence on reaction effect; and adding water into the fine mixture and the fermentation broth and carrying out a thermal reaction so as to allow the fine mixture, the fermentation broth and water to be mixed and synergism to be produced by all the ingredients. thus, excellent quality of the prepared flavoring agent is guaranteed and the flavoring agent can stimulate the hunger center of the sucking pigs after the sucking pigs eat the feed with the flavoring agent. Moreover, since the flavoring agent contains mint essence, the flavoring agent has special and exciting fragrance, can further stimulate the taste buds of the sucking pigs and allows the food intake of the sucking pigs to be greatly improved.

The invention discloses salty edible salt and a preparation method thereof. The salty edible salt comprises the following components: refined salt; fruit organic acid, wherein the mass of the fruit organic acid is 0.1%-5% of the mass of the refined salt, and the pH value of the fruit organic acid is 2-4; a yeast extract, wherein the mass of the yeast extract is 0.01%-0.1% of the mass of the refined salt; and an anti-caking agent. According to the invention, the salinity of the refined salt is improved directly through a pure natural, green and healthy formula, no potassium salt is introduced,and the perception of human taste buds on the salty taste is enhanced, so that people eat less salt without influencing the happiness of enjoying delicious foods, and the salt can be really reduced without reducing the salinity.

The invention relates to the technical field of food, in particular to a formula and a preparation method of Earl Grey black tea chocolate fudge. The preparation method comprises the following steps:preparing a cake base, preparing a fudge, artificially bonding the cake base and the fudge, packaging by using a special sweet wrapper, and refrigerating and preserving at a low temperature of less than or equal to 5 DEG C to obtain a finished product. The appearance structure of the fudge is changed, the fudge is originally presented in the form of slices, the size is just proper, and the fudge is easy to eat without throat blockage; the combined structure is originally created; no chemical additive, gelatin and other chemical additives are not added in the whole process, so that other riskscaused by fudge are reduced; the fudge melts in the mouth, does not stick to teeth and can be absorbed quickly, so that people with hypoglycemia or needing to supplement sugar can be quickly suppliedwith energy to quickly prevent body collapse; the cake base is made of butter, milk, flour and eggs, so that nutrition required by the body can be provided and meal replacement can be realized; a purecopper pot is used for artificial slow-fire sugar boiling, so that the fudge is heated uniformly, is viscous in the texture and glossy and translucent in luster, has a unique Earl Grey black tea chocolate taste, has silky mouthfeel, and stimulates taste buds with sweet and delicious taste.

The invention discloses a bitterness-preventing tool for oral medicines, and belongs to the technical field of oral medicine feeding auxiliary appliances. The bitterness-preventing tool for oral medicines comprises a suction tube. A first channel for conveying medicines is arranged in the suction tube. A medicine liquid inlet is arranged at one end of the suction tube. The other end of the suctiontube is provided with a medicine liquid outlet. The medicine liquid inlet and the medicine liquid outlet communicate with two ends of the first channel, respectively. The sectional area of the medicine liquid inlet is larger than that of the medicine liquid outlet, and the medicine liquid outlet is located on the upper side of the other end of the suction tube. According to the invention, the medicine liquid outlet is arranged on the upper side of the end of the suction tube, and the sectional area of the medicine liquid inlet is larger than that of the medicine liquid outlet, so that medicines parabolically flow out of a first outlet and goes straight to the throat. The flow rate of the medicines flowing through the medicine liquid outlet is relatively increased, thereby increasing rangeof the medicines, and promoting the medicines to go straight to the throat without contact with the taste buds of the tongue. The bitterness-preventing tool for oral medicines has the characteristicsof simple structure and convenient use.

The invention belongs to the field of freeze-dried durian and preparation methods thereof, and particularly relates to freeze-dried durian and a preparation method thereof. Yoghurt powder provided by the invention has the functions of being high in nutritional value, helping digestion, being easy to absorb, inhibiting generation of enterotoxin and the like, can prolong life of people, and is a high-grade nutritional and curative-effect food for infants, the old, the weak and the sick patients, so that the dried durian not only has better nutritional value, but also is convenient for promoting digestion of eaters; mangosteen powder has the effects of clearing heat and reducing internal heat, so that internal heat in the durian can be neutralized, and the taste of the product can be improved; and finally, longan honey is adopted as honey, so that the taste of the product can be enhanced, taste buds of consumers are stimulated, and the sales volume of the product is indirectly promoted.

The invention relates to the technical field of devices assisting in medicine taking, and discloses an oral cavity sleeve assisting in medicine taking. The oral cavity sleeve assisting in medicine taking comprises an oral cavity sleeve body, wherein a cavity part is arranged in the oral cavity sleeve body, a cavity inlet is formed in the front end of the oral cavity sleeve body, the cavity inlet communicates with the cavity part, a connecting part extending downwards is arranged at the rear end of the oral cavity sleeve body, a cavity outlet is formed in the connecting part and communicates with the cavity part. A medicine taking person can conveniently put the oral cavity sleeve assisting in medicine taking into the oral cavity when taking medicines, the oral cavity sleeve body and the connecting part are arranged in the oral cavity and the throat respectively, and the tongue and the throat of the medicine taking person are completely covered with the oral cavity sleeve assisting in medicine taking, so that the medicines (such as traditional Chinese medicines) enter the cavity part from the cavity inlet and then flow to the lower end of the esophagus of a human body from the cavity outlet, the medicines do not make contact with the tongue and the front end of the esophagus in the whole process, taste buds on the tongue and the throat are prevented from making contact with themedicines, and finally the situation that the medicine taking person generates bitterness to refuse taking the medicines is avoided.

The invention discloses a drinking utensil which is used for solving the problem that children resist to drinking bitter medicines when getting sick. When in use, two straws are placed in the oral cavity of a child, and the outlets of the two straws are at different positions in the oral cavity: one long straw cooperates with one short straw. The short straw outlet is located at a normal sucking position of the middle front portion of the tongue surface, and the long straw outlet crosses over the taste bud area where the tongue surface can taste and reaches the throat or a position below the throat. The inlet ends of the two straws are respectively connected to the two liquid containers. The long straw is connected to an extrudable container, and the container is used for containing a bitter medicine liquid; and the container connected to the short straw is used for containing a sweet drinking liquid. In the using process, children are induced to suck and swallow the sweet drinking liquid through the short straw by utilizing the sweet drinking liquid, meanwhile, the bitter medicine liquid in the medicine liquid container is sucked or squeezed into the medicine liquid container by parents at the swallowing moment, and the bitter medicine liquid is directly guided to the throat or the part below the throat after the long straw crosses over the taste bud area of the tongue surfaceand is swallowed into the stomach together with sweet drinking liquid swallowed to the throat. The taste of people mainly depends on taste bud cells distributed on the tongue surface of the tongue, and the bitter medicine liquid is not in contact with taste bud cells when passing through the oral cavity, so that children only taste the sweet taste of the drinking liquid and cannot taste the bitter taste of the medicine liquid in the swallowing process, the purpose of enabling the children to unconsciously and smoothly finish drinking the bitter medicine is achieved, and the problem faced by vast parents that the children resist to drinking the bitter medicine after illness is solved.

The invention discloses Chinese herbal medicine mouthwash and a preparation method thereof, and belongs to the technical field of mouthwash preparation. The Chinese herbal medicine mouthwash is prepared from raw materials, by weight, 1-5 parts of cortex cinnamomi extract, 5-10 parts of folium mori extract, 4-7 parts of flos caryophylli extract, 3-8 parts of herba pogostemonis extract, 1-5 parts of herba taraxaci extract and 10-20 parts of herba menthae extract. The Chinese herbal medicine mouthwash has a good halitosis removal effect, can effectively improve the flora environment in an oral cavity, does not color the surfaces of teeth and oral mucosa, does not cause the problem of taste bud and taste decline, and has no adverse effect on human health.

The invention provides colored effervescent beads containing haematococcus pluvialis-derived astaxanthin and a preparation method of the colored effervescent beads, and relates to the technical field of effervescent tablet processing. The colored effervescent beads are prepared from the following raw materials of an effervescing agent, a filling agent, a lubricating agent, a flavoring agent, astaxanthin microcapsule powder and food coloring, wherein astaxanthin in the astaxanthin microcapsule powder is extracted from haematococcus pluvialis. The colored effervescent beads are bright in color and rich in taste and nutrition, and brand new experience of vision and taste buds can be brought to people.

The invention provides 3D carved eye-protecting tremella jelly capable of sublimating vision and taste buds, relates to a preparation method, and belongs to the field of food, aiming at the defects that products in the existing market are not novel enough, not outstanding enough in function, single in market and the like. The jelly consists of the following raw materials in parts by weight: 10-25 parts of tremella, 25-40 parts of jelly powder, 5-10 parts of a thickening agent, a small amount of white granulated sugar and lemon juice, 5-15 parts of milk, and 10-25 parts of juice of blueberries, Chinese wolfberry fruits, kiwi fruits and the like. According to the jelly, the eyesight-improving food materials and the tremella liquid are added to replace jelly liquid, a 3D carving technology is adopted, and the jelly is an eye-protecting food with improved color and flavor and an active substance with the effects of effectively relieving visual fatigue, preventing and treating radiation damage and the like, so the effects of beautifying and protecting eyes are achieved, and the jelly has a wide market prospect.

The invention discloses a fixed acid stimulation recovery device for cerebral apoplexy, which comprises a fixed shell, a micro air pump, a Laval nozzle, an acid powder chamber, a scaling nozzle, a conduit, an air storage chamber and a probe; the micro air pump is installed on the side wall of the fixed shell on; the output end of the miniature air pump extends into the inside of the fixed shell; the input end of the Laval nozzle is connected to the output end of the micro air pump; the zoom nozzle is installed inside the fixed shell; the nozzle of the zoom nozzle is connected to the output end of the Laval nozzle Corresponding; the acid powder bin is installed on the upper end of the fixed shell, and acid powder is installed in the acid powder bin; the bottom of the acid powder bin is connected to the inside of the fixed shell; one end of the conduit is connected to the zoom nozzle, and the other end protrudes from the inside of the fixed shell; the gas storage chamber is connected to the conduit The end; the probe is connected to the air storage chamber; the invention uses the Laval nozzle and the zoom nozzle as the carrier, drives the acid powder to the patient's mouth through the airflow, activates the patient's taste buds, further promotes the secretion of saliva, and reconstructs the swallowing reflex.

The invention provides high-calcium soft sweets. The high-calcium soft sweets comprise the following raw materials in parts by weight: 1-4 parts of grease; 0.5 to 2.5 parts of a gel agent; and 3-10 parts of a calcium agent. According to the invention, the grease, the gelling agent and the calcium agent are compounded; the smooth taste of the grease can cover taste buds to form a shielding effect, so that the powdery taste and astringent taste of the calcium agent can be shielded. On the basis of high-content calcium, the calcium agent is embedded and fully dispersed through the proportioning of grease, an emulsifying agent and the calcium agent and an emulsifying process, so that the powdery feeling and astringent taste of the calcium can be effectively covered. Through the proportion of the gels, the viscosity of the system can be improved, so that the calcium agent is fully suspended and dispersed, and the situation that the calcium agent is re-gathered to cause system damage and poor taste is avoided. The gel can assist grease emulsification in addition to a soft sweet forming effect, has an effect of stabilizing a system, and prevents grease from being separated out. The calcium agent is treated by adopting grease, so that the influence on gel stability due to mutual reaction with colloid under excessive heating during boiling is avoided, and the bitter taste caused by water treatment is also avoided.

A collection of therapies that are useful in a speech pathology setting, the common denominator of the therapies is that they each make use of chewing gum. Chewing gum administered to a patient can be used to treat swallowing disorders and oral motor impairments. In a major aspect of the invention, a series or kit of chewing gums of varying hardness can be used to treat mastication disorders. The gum exercise program will use the varying gum hardnesses as exercises for the muscles of the mouth, mastication, oral motor, sensory / stimulation, and swallowing therapeutic interventions. The instant therapies are more functional than existing dysphagia and oral motor interventions because they are similar to masticating real food by eliciting saliva production and taste buds from the gustatory response of the lemon and sour flavors. In addition, for sensory / stimulation exercises, the varying degrees of gum hardness, along with the lemon and other flavors, provide sensory feedback.

The invention belongs to the technical field of food processing, and particularly relates to alga-containing short biscuit and a preparation method thereof. The method comprises the steps as follows:(1) alga pretreatment: taking algae and performing homogenization or taking alga dry powder; (2) raw material preparation: selecting self-raising flour, alga homogenate or alga dry powder, vegetable oil, salt, baking soda, aluminum-free baking powder and aromatic flavoring as raw materials; (3) powder mixing and dough kneading: taking alga homogenate or alga dry powder as raw materials, mixing theraw materials with other raw materials, and kneading dough; (4) rolling forming; (5) baking; (6) cooling; and (7) packaging. The alga-containing short biscuit has the beneficial effects as follows: the produced biscuit contains no sugar, has diversified flavors, has better antioxidant activity and can increase healthcare effects while meeting taste buds of people.