170results about "Crystallization auxillary selection" patented technology

The invention relates to the technical field of ammonia desulfurization, and in particular to an integrated device for promoting crystal growth, comprising a desulfurization crystallization tower, a steam generator is arranged on one side outer wall of the desulfurization crystallization tower, a steam transmission end of the steam generator is connected to a first steam transmission pipe, and one end of the first steam transmission pipe runs through the interior of the desulfurization crystallization tower, a discharge port is through-connected on the bottom outer wall of the desulfurization crystallization tower, and a slurry crystallization tank is arranged on one side outer wall of the desulfurization crystallization tower; in the ammonia desulfurization process of the invention, the waste gas is desulfurized in the desulfurization tower, and the solution is concentrated and concentrated in the desulfurization tower by using high-temperature steam as a heat source, so that the slurry in the desulfurization tower is crystallized and precipitated; in the process, a feed pump is operated to pump the slurry with fine crystals in the desulfurization tower into the slurry crystallization tank, and the fine crystal slurry is crystallized by separating a part of the solvent in the slurry crystallization tank in combination with slow stirring, thereby increasing the crystallization; the crystallization inside the tower and outside the tower are combined to effectively increase the crystallization.

The invention relates to the technical field of insecticides, and discloses an indoxacarb finished product crystallization device and method.The indoxacarb finished product crystallization device comprises a supporting bracket, a stirring tank is arranged at the top of the supporting bracket, an opening plate is arranged on one side of the stirring tank, a mounting frame is arranged at the top of the stirring tank, a driving source is arranged on the mounting frame, and a rotating shaft is arranged at the output end of the driving source; a fixing frame is arranged at the bottom of the inner wall of the stirring tank, and a homogenizing assembly is arranged on the fixing frame; the fixing frame is further provided with a vibration assembly. The homogenizing assembly is used for uniformly mixing the indoxacarb finished product solution in the stirring tank; the vibration assembly is used for reducing the phenomenon of local supersaturation of liquid in the stirring tank through vibration. Compared with the prior art, crystal agglomeration can be reduced, the particle distribution uniformity can be improved, the wall surface scaling risk can be reduced, the cleaning and maintenance frequency can be reduced, and the production efficiency and the product quality can be improved.

The invention discloses a synthesis method of a chiral polyaniline nano material and application of the chiral polyaniline nano material in amino acid chiral crystallization. The preparation method comprises the following steps: ultrasonically dissolving unichiral tartaric acid, an aniline monomer and N-phenyl p-phenylenediamine in water, adding a certain volume of an ammonium persulfate aqueous solution to initiate polymerization, centrifuging after complete reaction to obtain a polyaniline-tartaric acid (PANI-TA) chiral nano material, and carrying out ammonia water dedoping and hydrochloric acid solution re-doping to obtain a polyaniline-hydrochloric acid (PANI-HCl) chiral nano material. And finally, respectively adding the polyaniline-hydrochloric acid chiral nano-material into a supersaturated leucine, alanine or tryptophan aqueous solution to induce chiral crystallization, wherein the result shows that the polyaniline-hydrochloric acid chiral nano-material can induce one configuration of amino acid to crystallize more quickly and the other configuration of amino acid with enantiomeric excess remains in the solution. The chiral polyaniline nano material prepared by the method avoids introduction of other chiral molecules in chiral crystallization, is beneficial to separation of products, has the advantages of simplicity in operation, low cost and the like, and has a wide application prospect in the field of chiral resolution.

This application relates to the field of functional crystalline material preparation and microfluidic application technology, specifically disclosing a method and product for preparing formate crystals using core-shell microcapsules, including the following steps: (1) dissolving a solid alkaline raw material in a formic acid solution to prepare reaction solution a; (2) separately conveying polymer solution A and polymer solution B with phase separation characteristics, and reaction solution a, so that they are mixed at the intersection of microchannels to prepare dispersed phase b, which is then introduced into the assembly zone for phase separation assembly to form core-shell microcapsules; (3) the core-shell microcapsules are crystallized in a continuous temperature-changing crystallization zone to form formate solid; (4) the formate solid is collected, washed and dried sequentially to obtain the target product; (5) the oil layer is continuously extracted and returned to the assembly zone for recycling. The formate crystals prepared in this application not only have a large particle size, but also exhibit good size uniformity and morphological repeatability, and have the advantages of high throughput, green environmental protection, and simple operation.

The invention belongs to the field of fluorescent sensors, and relates to an Ag-CP fluorescent probe material as well as a preparation method and application thereof. The structural formula of the fluorescent probe material is [Ag (HL) (L)] n, and an HL ligand is 4-(3, 5-dimethyl-1H-pyrazole-1-yl) benzoic acid. Ag-CP is prepared by the following method: dissolving HL and AgNO3 in H2O to obtain light brown turbid liquid, carrying out high-temperature reaction on the light brown turbid liquid, and cooling to obtain the Ag-CP. The Ag-CP material can identify tryptophan (Trp) molecules in an aqueous solution with high selectivity and high sensitivity, has good stability and anti-interference ability in fluorescence identification ability, and can be used as an excellent Trp molecule identification fluorescence sensor.

A process for producing a polymorphic or pseudo-polymorphic crystalline phase from a plurality of compounds (C,D,S1,S2), comprising the steps of preparing (I) a supersaturated solution from said compounds, homogenizing (II) said supersaturated solution in an ultrasonic bath, transferring (III) the supersaturated solution into a plurality of heated tubes (54), aging (V) the solutions transferred into the tubes for a determined period, exposing said tubes (54) to a pulsed and polarized laser beam before and / or during exposure, monitoring in situ the nucleation and then the growth of co-crystals inside said tubes (54), and filtering the exposed solutions to recover co-crystals larger than a predetermined minimum size.This process is implemented to carry out co-crystallization from at least one active substance (D) and one co-former (C) in at least one first solvent (S1) and one second solvent (S2), and it further comprises two preliminary steps: establishing a phase diagram from the respective physicochemical characteristics of said active substance (D), said co-former (C), said first solvent (S1) and said second solvent (S2), and then determining, from said phase diagram thus established, concentration, temperature and exposure conditions providing a stable phase for the production of co-crystals. See Figure 4.

The invention discloses a processing method for fractionation and rapid crystallization of palm oil, which comprises the following steps: (1) heating and controlling a palm oil raw material to be fractionated to 55-65 DEG C (crystal breaking), pumping the palm oil raw material into a crystallizing tank, and then cooling the palm oil raw material to about 25 DEG C under the action of rapid cooling of cooling water (or chilled water) and stirring; (2) continuously reducing the temperature of the palm oil raw material in the crystallizing tank by using chilled water, adding a certain proportion of palm oil (solid-liquid mixture) which is completely crystallized and is in an unseparated state into the crystallizing tank at the interval of 25.0-18.0 DEG C as a seed crystal, and controlling the stirring speed of the crystallizing tank at 15-30r / min until the palm oil raw material is completely cooled and crystallized; (3) after crystallization is completed, if seed crystals need to be added into the crystallizing tank which is cooling and crystallizing, pumping the seed crystals into the crystallizing tank which needs to be added with the seed crystals through a pump; otherwise, immediately pumping into a membrane filter for filtering and separating (preventing the tank from being burnt) to obtain liquid oil and stearin. The palm oil seed crystal is added, so that the crystallization time can be shortened; and through seed crystal induction, the formation of stable-form crystals is accelerated, excessive crystallization is avoided, and the interception loss of filtration is reduced, so that the liquid oil yield is improved.

Method for producing electronic grade nickel sulfate from nickel powder, crystallization apparatus, and control thereof The present invention provides a method for producing nickel sulfate, and nickel sulfate produced thereby. The process includes acid leaching, copper removal, acid adjustment, concentration, cooling crystallization, drying and sieving, and secondary leaching. Oxidation In the calcination furnace, the temperature is 400 to 700°C, and 1 kg of compressed air is used for each kilogram of nickel powder. ~5m 3 The reaction time is 1.0 to 2.5 hours, and the temperature during acid immersion is controlled to 45 to 70°C. Then, add dilute sulfuric acid to control the pH to 0.5-1.5 and react for 1-3 hours. The copper removal is to replace the copper with nickel powder, and the acid conditioning is to use nickel hydroxide or The pH is adjusted to 2.5-4.5 using nickel carbonate, and the filtrate is concentrated by The cooling crystallization method is to obtain nickel sulfate crystals and return the mother liquor to the concentrate. Drying and sieving is to add the undersieved material to the crystallizer as seed crystals, and secondary leaching is to Dilute sulfuric acid is added to the leaching slag, and it is reacted with nickel sulfate or hydrogen peroxide until nickel is less than 0.1%. If the first stage is full, the second leaching is continued. The crystallizer is a crystallizer that is connected in series with a second-stage crystallizer and a third-stage crystallizer. A crystallization frame, an oscillator provided under the crystallization frame, and an oscillator provided at the exit end of the crystallization frame. The crystallization frame is a rectangular parallelepiped. The bottom of the ribs are evenly spaced, with a cross section of a circular arc. The distance between two adjacent ribs is S is 1 / 25 to 1 / 15 of the width of the crystallization frame, and either the width b or the height h of the rib The width of the crystallization frame is 1 / 100 to 1 / 150 of the width of the crystallization frame. It does not add any new impurity ions, and does not add any oxidizing agent. The nickel sulfate crystal particles produced are uniform and are free of the static generation. This avoids caking of very large particles, irregularly shaped particles and crystals.

The invention discloses a method for separating high-purity chlorogenic acid and neochlorogenic acid from a stevia rebaudiana chlorogenic acid product based on membrane coupling extraction crystallization. The method comprises the following steps: preparing a first to-be-treated solution by taking the stevia rebaudiana chlorogenic acid product as a raw material; treating the first to-be-treated liquid through an ultrafiltration membrane and a nanofiltration membrane in sequence to obtain a trapped fluid II, concentrating the trapped fluid II, and adjusting the pH value to obtain a second to-be-treated liquid; extracting the second to-be-treated liquid with an ethyl acetate-n-butyl alcohol saturated aqueous solution to obtain a raffinate phase I and an extract phase I; adjusting the pH of the raffinate phase I to obtain a third to-be-treated solution; extracting the third to-be-treated liquid with an ethyl acetate-n-butyl alcohol saturated aqueous solution to obtain a raffinate phase II and an extract phase II; drying the extract phase I, crystallizing, pulping and purifying to obtain high-purity chlorogenic acid; and drying the extract phase II, crystallizing, pulping and purifying to obtain the high-purity neochlorogenic acid. According to the method, membrane separation, solvent extraction and fractional crystallization are coupled, and high-efficiency and high-selectivity separation and purification of chlorogenic acid and neochlorogenic acid in a stevia rebaudiana chlorogenic acid product are realized.

The invention relates to a method for producing a polymorphic or pseudo-polymorphic crystalline phase from a plurality of compounds (C, D, S1, S2), the method comprising steps of preparing (I) a supersaturated solution from the compounds, homogenizing (II) the supersaturated solution in an ultrasonic bath, transferring (III) the supersaturated solution into a plurality of heated tubes (54), aging (V) the solutions transferred into the tubes for a predetermined period of time, exposing the tubes (54) to a polarized pulsed laser beam before and / or during exposure, followed in situ by nucleation and then growing cocrystals inside the tubes (54), and filtering the exposed solutions in order to recover cocrystals having a size greater than a predetermined minimum size. This method is carried out in order to obtain cocrystallization from at least one active substance (D) and a coformer (C) in at least a first solvent (S1) and a second solvent (S2).

In the crystallization system of the lithium hexafluorophosphate of the present invention, a first-stage crystallization kettle is connected to a lithium hexafluorophosphate mother liquor supply source through a lithium hexafluorophosphate mother liquor supply line; further connected to the lithium hexafluorophosphate mother liquor supply source through a mother liquor heat exchange line connected with a mother liquor heat exchanger; and further connected to a second-stage crystallization kettle through a first mother liquor delivery line configured to deliver lithium hexafluorophosphate mother liquor, a second-stage crystallization kettle is connected to a third-stage crystallization kettle through a second mother liquor delivery line configured to deliver lithium hexafluorophosphate mother liquor, a third-stage crystallization kettle is connected to a fourth-stage crystallization kettle through a crystalline particle delivery line configured to deliver small crystalline particles in the third-stage crystallization kettle; and further connected to a next process device through a first discharging line, and a fourth-stage crystallization kettle is connected to a next process device through a second discharging line. The crystallization system of lithium hexafluorophosphate of the present invention enables different crystallization stages to be carried out separately in different crystallization kettles, so as to realize continuous feeding and continuous discharging in the course of crystallization.

The invention relates to a eutectic freeze crystallization apparatus of liquid, comprising: a eutectic freeze crystallization chamber (200) comprising an internal space having a first portion and a second portion and configured to receive said liquid via a feeding inlet arranged within the eutectic freeze crystallization chamber; mixing means arranged within the internal space at the first portion and configured to mix the liquid therein; a cooling element configured to cool the liquid within the internal space for lowering temperature of the liquid such that ice and salt crystals will be formed within the liquid; and conveyor means extending at least within the internal space and configured to convey at least part of the ice and salt crystals from the liquid towards a first outlet arranged at the second portion and to feed out via the first outlet the at least part of the ice and salt crystals from the internal space of the eutectic freeze crystallization chamber. The ice and salt crystals are separated in a separation unit (333).

To provide an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor.SOLUTION: The present invention relates to a method for producing a compound of the formula Ia implemented by a convergent synthesis method. The method comprises: reacting a compound of the formula 2 with a compound of the formula 3, and subjecting the resultant to a cyclization reaction to obtain a compound of the formula 4; subjecting the resultant to dehydration or amidation, reacting the resultant with a compound of the formula 5, and performing reduction to obtain a compound of the formula 6; and reacting the resultant with a compound of the formula 7 and performing deprotection and reduction.SELECTED DRAWING: Figure 1

The invention relates to a solvent extraction method for removing calcium. In the method, an aqueous extraction solution is dispensed in an organic phase having a lower density than the aqueous extraction solution. The steps of the method include dispensing droplets of an aqueous extraction solution in an upper portion of a solvent extraction unit, passing the droplets through an organic phase towards a bottom of the solvent extraction unit, collecting the droplets at the bottom of the solvent extraction unit into an aqueous phase layer, and removing the aqueous slurry containing the precipitated calcium compound from the bottom portion of the aqueous phase layer at the bottom of the solvent extraction unit. The invention also relates to a solvent extraction unit for carrying out the method according to the invention.

The invention relates to a method for producing solid particles (13) from a liquid or semi-liquid composition (1), in particular from an oil composition, a fat, a wax or another fat compound, using at least one device (2) for forming a liquid or semi-liquid jet of the product, followed by a step of quick-freezing or total or partial crystallisation of the jet thus formed, characterised by the implementation of the following measures: - producing one or more streams (12) of the composition by means of the one or more forming devices, which streams enter the upper portion of a reaction chamber (3) and circulate within this reaction chamber from top to bottom; characterised in that a machine is used for cutting the one or more product streams with a wire or a disc (14) rotating at a given and selected speed, wherein the movement of the wire or the disc causes substantially cylindrical product particles to be transformed into spherical or substantially spherical particles as they fall through the chamber towards the lower portion of the chamber where they are recovered (5)°.

The invention discloses a circulating crystallization device, which relates to the technical field of crystallization, is used for solving the problem that crystal grains are damaged in a crystal growth process, and comprises a circulating pipeline, and a cooling device, a plurality of crystal growth devices, a circulating pump and a turnover tank are arranged on the circulating pipeline; the crystal growth device is arranged on the circulating pipeline and comprises a feeding hole formed in the top of the crystal growth device; the buffer cavity is communicated with the feed port, and an overflow port is formed in the side wall; the crystal growth cavity is communicated with the buffer cavity, and the bottom of the crystal growth cavity is conical; the discharge hole is formed in the bottom of the crystal growth device; the material tank is communicated with the cooling device through a connecting pipe I; a first material is cooled by a cooling device along a connecting pipe I, a part of the first material enters a crystal growth cavity through a feeding hole and a buffer cavity for crystal growth, so that a second material and a third material are separated from the first material, the second material enters another cooling device through an overflow hole, and the third material enters a circulating pump along a circulating pipeline; and the circulating pump drives the third material to enter the turnover tank.

The invention relates to the technical field of salt preparation systems, in particular to a sodium chloride and sodium sulfate large-particle salt preparation system, which comprises a crystallization separation module, a sodium chloride and sodium sulfate large-particle salt preparation module and a sodium chloride and sodium sulfate large-particle salt preparation module, the fine crystal elimination and crystallization module comprises a crystal grading and growing kettle, a thickener and a centrifugal machine, a solution is evaporated and crystallized through the crystal separation module and conveyed to the fine crystal elimination and crystallization module, and the fine crystal elimination and crystallization module carries out grading and growing on the solution and forms crystals with different particle sizes; and the floating fine crystal is conveyed to the fine crystal eliminating and dissolving module again to carry out fine crystal dissolving on the unsaturated solution, the dissolved solution is conveyed to the fine crystal eliminating and crystallizing module again, and after the sinking particle crystal is thickened, centrifugal dewatering is carried out to form a crystal with a large crystal form particle size and a large crystal form particle size. And the crystal is round and regular in morphology, so that the crystal is good in flowability, anti-caking, high in strength and not easy to break, and industrial subsequent treatment is greatly reduced.

The invention discloses a built-in calcium fluoride crystallizer based on a coagulative precipitation tank, a first guide cylinder and a second guide cylinder are respectively fixed on opposite side walls in the coagulative precipitation tank, a fluorine-containing wastewater inlet pipeline conveys fluorine-containing wastewater into the first guide cylinder, a calcium-containing medicament inlet pipeline conveys a calcium-containing medicament into the second guide cylinder, and the first guide cylinder and the second guide cylinder are communicated with each other. The first propeller and the second propeller are fixed in the first guide cylinder and the second guide cylinder respectively, the first propeller vertically pushes flow downwards, the second propeller vertically pushes flow upwards, the stirrer can stir liquid in the coagulating basin, and the crystal discharging device can regularly discharge crystal precipitates at the bottom of the coagulating basin into the cyclone separator. The cyclone separator can perform cyclone separation on large-particle crystals and small-particle crystals, the large-particle crystals are discharged from a crystal outlet of the cyclone separator, and the small-particle crystals are discharged from a water outlet of the cyclone separator along with water flow and enter the coagulating basin. The medicament cost is reduced, and the improvement cost is low.

The present invention relates to a method for purifying a crude diester monomer feed, the method comprising the steps of: a) mixing the crude diester monomer feed with an aqueous solvent at a temperature of 60-150°C to obtain an aqueous mixture of diester monomers, adjusting the amount of aqueous solvent injected so that the crude diester monomer feed accounts for 20-90% of the total weight of the aqueous mixture of diester monomers; b) adsorbing the aqueous mixture of diester monomers at a temperature of 60-150°C and a pressure of 0.1-1.0 MPa to obtain a purified monomer effluent.

The present invention provides a continuous falling film melt crystallizer, including a cylinder, wherein a feeding port and a discharging port are respectively provided in a top region and a bottom of the cylinder; crystallization zones are sequentially provided within the cylinder in several levels from top to bottom; each crystallization zone is provided with multiple vertically arranged crystallization tubes; heat exchange tubes are sleeved onto respective crystallization tube, with crystallization tubes and heat exchange tubes in adjacent crystallization zones being in one-to-one correspondence and in communication with each other; crystallization tubes in the top level and the crystallization tubes in the bottom level are in communication with the feeding port and the discharging port, respectively; a cooling / heating medium inlet / outlet communicating with top ends of the heat exchange tubes is provided on the cylinder for each level of crystallization zone, and in the bottom level of the crystallization zones, a cooling / heating medium inlet / outlet communicating with bottom end of the heat exchange tubes is provided in a lower region of the cylinder. In the present invention, cooling / heating medium inlet / outlets are additionally arranged in the middle of the cylinder, such that the heat exchange uniformity between a material supply to be purified and a cold medium in the upper region and lower region of the cylinder can be improved, and a uniformity of crystallization in the upper region and lower region of the cylinder is further improved.

The invention relates to a specific type of reactor (1) designed to perform chemical synthesis processes, for use in the production of cathode active materials for lithium-ion batteries.

The application discloses a method for digesting and separating fluorinated aluminum by program, which comprises the following steps: placing a catalyst with metal elements supported on alumina as a carrier into a reaction container of a cluster digestion device, adding hydrochloric acid and / or nitric acid, setting a digestion program, introducing inert gas for pre-pressurization, performing primary digestion, and simultaneously starting a condensation reflux atomizer; after the program is completed, adding hydrofluoric acid, setting a digestion program, and performing secondary digestion; after the digestion is completed, entering a cooling and crystallization program, performing cooling and crystallization, and separating to obtain a sample solution to be detected and a solid; the solid is dried and calcined to obtain fluorinated aluminum crystals, and the liquid is used for detecting the content of metal elements. The method is applied to the digestion treatment of the alumina sample with metal elements supported thereon, has a large sample treatment range, complete digestion, no volatile loss of elements, and can separate AlF3 in an alpha crystal form through the program digestion of the digestion device.

The disclosure relates to methods for crystallization of active pharmaceutical ingredients (APIs), wherein the crystallization and crystal growth is controlled. According to the method solid amorphous nanosized API and an aqueous solution comprising one or more polymers and / or copolymers are contacted so as to form a suspension comprising nanosized API in crystalline form.

A process for treating fluids for the removal of sulphate therefrom, the process comprising passing a fluid containing a sulphate and carbonate through a fluidized bed reactor; and, loading sulphate to said fluidized bed reactor at a rate that is greater than 1 kg of sulphate per square metre of said fluidized bed reactor per hour (kg SO4 / m2 / hr); thereby co-precipitating the sulphate and carbonate. The process must maintain the supersaturation levels of calcium sulphate within a predefined range of 100-450% and provides a loading rate of sulphate in the reactor that is greater than 1 kg of sulphate per square metre of reactor per hour (kg SO4 / m2 / hr).

The invention relates to the technical field of steel wire generation, in particular to a borax bath solution chloride ion removal system and method.The method comprises the steps that bath solution in a borax bath is extracted through a borax treater, and borax decahydrate seed crystals are scattered into the borax treater; a borax processor cools the tank liquid, borax decahydrate crystals are separated out, and pollution liquid is discharged; according to the method, the borax decahydrate crystals are separated out through the borax treater, pollution liquid containing the chloride ions is completely discharged, the separated borax decahydrate crystals are heated and dissolved, the borax bath liquid polluted by the chloride ions does not need to be scrapped, and the method has the advantages that the operation is simple, the cost is low, and the production efficiency is high. The method has the advantages of simple operation, no need of adding the borax bath solution, effective avoiding of the scrapping of the polluted borax bath solution, avoiding of most environment-friendly treatment cost, wide practical value, and application to wire drawing processes adopting on-line pickling and boronizing.

The invention relates to a eutectic freeze crystallization apparatus of liquid, comprising: a eutectic freeze crystallization chamber comprising an internal space having a first portion and a second portion and configured to receive said liquid via a feeding inlet arranged within the eutectic freeze crystallization chamber; mixing means arranged within the internal space at the first portion and configured to mix the liquid therein; a cooling element configured to cool the liquid within the internal space for lowering temperature of the liquid such that ice and salt crystals will be formed within the liquid; and conveyor means extending at least within the internal space and configured to convey at least part of the ice and salt crystals from the liquid towards a first outlet arranged at the second portion and to feed out via the first outlet the at least part of the ice and salt crystals from the internal space of the eutectic freeze crystallization chamber.

The present invention provides a method for efficiently obtaining a high-quality product. The present invention is a method for producing an easily polymerizable compound using a refining device having a crystallization tank for generating crystals of an easily polymerizable compound from a mother liquor of a solution containing an easily polymerizable compound or a slurry containing crystals of an easily polymerizable compound and / or a ripening tank for growing crystals of an easily polymerizable compound, and also having a washing column, the method for producing an easily polymerizable compound being characterized in that: the refining device furthermore has a line having ten or fewer bends, the ratio R / D of the curvature radius R and the line inside diameter D of the line exceeding 4, and the line being connected to at least one selected from the group consisting of the crystallization tank, the ripening tank, and the washing column; and the production method includes a step for sending a slurry containing crystals of the easily polymerizable compound through the line.

The invention discloses a crystallization method of fructose and crystalline fructose prepared by the crystallization method, and belongs to the technical field of crystallization. The fructose crystallization method comprises the following steps: taking isomerized fructose syrup, adding glucose oxidase, catalase and calcium carbonate under stirring and ventilation until the pH value is stable, and carrying out plate frame filtration to obtain a feed liquid A; filtering the feed liquid A through a microbial flocculant, and removing impurities through a ceramic membrane, an ultrafiltration membrane and an electrodialysis system at a certain temperature and pressure to obtain feed liquid B; evaporating and concentrating the feed liquid B, adding a nucleating agent and a sugar molecule integrating agent while stirring, and cooling and crystallizing in stages to obtain feed liquid C; and centrifuging the feed liquid C, and carrying out vacuum microwave drying to obtain crystalline fructose. The method is high in extraction yield and purity, large in treatment capacity, high in continuous degree and suitable for large-scale industrial production.

A static mixer crystallizer device includes at least one side wall defining a channel extending from a first end to a second end along a longitudinal axis. The channel receives a flow of a solution from the first end of the channel and expels the solution from the second end of the channel. The solution is a supersaturated solution comprising a fluid and dissolved salts. The device include a first structure disposed within the channel, the first structure comprising at least one surface comprising at least one of a reentrant surface, a crenellation, a concavity, or a corrugation configured to affect the flow of the solution through the channel to increase the turbidity thereof and accelerate a rate of crystal growth within the solution. The solution exiting the second end of the channel comprises salt crystals precipitated from the supersaturated solution.