The invention discloses a synthetic method of trans-1,4-cyclohexane diisocyanate, comprising the following steps: (1) mixing trans-1,4-cyclohexanedicarboxylic acid and thionyl chloride, heating Reflux, reclaim redundant thionyl chloride under reduced pressure, obtain trans-trans-1,4-cyclohexanediformyl chloride; (2) add toluene to trans-1,4-cyclohexanediformyl chloride , benzene or xylene, heated to 45-75°C, and then added sodium azide to obtain a mixture; (3) keep the mixture at a temperature of 45-75°C for 0.5-1.5 hours; remove insoluble matter by filtration, and recover under reduced pressure Toluene, rectification, in trans-1,4-cyclohexane diisocyanate. The synthesis method of the invention has simple process route, easy-to-obtain raw materials, short reaction cycle, and is suitable for large-scale industrial production.