1results about How to "Reduce liquid viscosity" patented technology

This invention relates to the field of materials science and technology, providing a porous gel scaffold for partitioned drug delivery, its preparation method, and its applications. The modification steps in this invention are simple, allowing for easy acquisition of the target product. The purification method is straightforward, and the modified monomers exhibit good biocompatibility and high safety. This invention modifies hyaluronic acid with norbornene and gelatin with thiol groups, effectively reducing its liquid viscosity and facilitating emulsification in liquid microfluidic chips. The synthesized microgels exhibit high uniformity in particle size, strong controllability, and stable drug loading concentration in a single gel. With the assistance of photocurable cyclodextrin, the aqueous solubility of non-water-soluble drug molecules can be significantly improved. The porous gel scaffold prepared by secondary assembly of the microgels used in this invention can better simulate the three-dimensional environment in vivo and can be used as a modular tissue engineering repair material for regenerative medicine drug / gene targeted delivery and stem cell loading.