The invention discloses a precise reference type production processing flow for an engine connecting rod. The production processing flow comprises the following steps of firstly, carrying out the first phase of processing before cutting of a connecting rod body and a cover, respectively carrying out blank inspection, magnetic particle inspection and rough drilling of a small-end hole, and preparing for the processing of upper and lower end surfaces, the small-end hole, two planes at bolt hole ends, an outer surface of a large-end hole, and the like in the precise basis way; then, carrying out processing after cutting of the connecting rod body and the cover, roughening the large-end hole, except for precise referencebasis, and preparing for the roughening of the bolt hole and the combining surface, and the processing of a bearing counterbored groove; and carrying out processing after cutting of the connecting rod body and the cover, and sequentially carrying out the finishing of the large-end hole after the assembly of the connecting rod, the finishing of the upper and lower end surfaces, and the finishing of the large-end hole and the small-end hole. The production processing flow has the beneficial effects that the speed of the linear movement can be smoothly adjusted, the running precision of the machine is favorably improved, the service life of the machine is prolonged, the arrangement is conveniently and flexibly realized according to requirements, the operation controllability is improved, and the labor strength is reduced.