The invention discloses a preparation method of a mouth mask chip for preventing PM2.5 and ozone. The method comprises the following steps: 1, nanometer silica and nanometer titanium dioxide are uniformly mixed, glycerin or polyethylene glycol is added in a dropwise dropping mode, the three materials are fully melted and placed in purified water, the mixture is stirred and suspended for standby; 2, sodium polyacrylate and guar gum are uniformly mixed, the materials are poured into the mixture in the step 1, and materials are fully dissolved for standby; 3, betaine and urea are taken and uniformly mixed, the materials are placed in 25-35 parts of purified water at 55-65 DEG C, and uniform stirring is carried out for standby; 4, the mixture in the step 2 and the mixture in the step 3 are mixed again with uniform stirring, homogenizing is carried out in order to prepare aqueous composite non-setting adhesive; 5, carbon fiber is used as a carrier, and the aqueous composite non-setting adhesive is smeared on carbon fiber. The method has the advantages of simple manufacture, standard technology, usage convenience, and easy promotion, and the method can be widely applied to the fields ofenvironmental protection, medicine, new materials, and the like.