The invention discloses a circuit security constraint-considering provincial grid AGC (
automatic generation control) unit dynamic optimization scheduling method. The method comprises the following steps of firstly, inputting provincial grid basic data, i.e., acquiring a 
network structure and related data of a provincial grid, acquiring AGC related data, and setting an evolutionary 
programming parameter; secondly, randomly generating an initial 
population of control variables (a regulating instruction and a regulating rate), and performing 
adaptive mutation operation on antibodies in the 
population; thirdly, correcting the antibodies according to a regulating instruction constraint, a regulating rate constraint and the minimum continuous climbing time constraint, and comprehensively considering target functions of a CPS1 (control performance standard) index and AGC regulation 
ancillary service charge, and inequality constraints of tie-line power deviation, 
system frequency deviation, CPS indexes, unit output and circuit safety, and calculating the 
adaptive value of each 
antibody in the 
population; finally, on the basis of adaptability, evaluating and selecting the antibodies, and performing termination judgment to realize decision on the regulating instruction and the regulating rate of an AGC unit.