3 results about "Hypoxic stress" patented technology

This invention discloses a method for improving the environmental stress resistance of fish by subjecting them to intermittent hypoxia training. The method includes: maintaining dissolved oxygen (DO) in the water at normoxic levels; setting a fixed time window daily to begin deoxygenation treatment, causing DO to drop to a target hypoxic level within a specified time and maintaining this target hypoxic level for a period of time; subsequently, reoxygenating to restore DO to normoxic levels. This intermittent hypoxia training is conducted continuously, with water quality indicators maintained within a suitable range for the target fish during the training period. After the training is completed, the resistance of the target fish is evaluated. This invention is simple to operate. After intermittent hypoxia training, the LOE threshold of the target fish decreases under hypoxic stress, and their hypoxia tolerance is improved. The fish also exhibit enhanced antioxidant capacity and reduced lipid peroxidation levels under hypoxic, high-temperature, and high-ammonia nitrogen stress, providing cross-protection for fish populations growing under various environmental stresses.

The invention discloses an application of a CHRNA3 agonist in treatment of memory down-regulation induced by low-pressure and low-oxygen stress. It is found for the first time that a CHRNA3 agonist can effectively relieve learning and memory ability decline induced by hypoxia stress, based on the regulation and control relation of miR-24 and CHRNA3, the computer-aided drug screening method, system and equipment based on miR-24 and CHRNA3 are provided, a new thought and direction are provided for treatment of learning and memory ability decline induced by hypoxia stress, and the method, the system and the equipment have good application prospects. The application prospect is wide.

The invention relates to a preparation method of an anti-hypoxia stress mixed fatty alkanol aquatic feed additive, and belongs to the technical field of aquatic feed additives. The preparation method of the aquatic feed additive comprises the following steps: 1) melting mixed fatty alkanol in hot ethanol; 2) adding a compound emulsifier of soybean lecithin and sorbitan monooleate, and performing hot melting; (3) slowly adding vegetable oil of which the temperature difference with the system temperature does not exceed 2 DEG C; 4) carrying out ultrasonic emulsification to prepare an emulsion; (5) adding the emulsion into a premix formed by corncob powder, sodium butyrate and calcium carbonate, and stirring and mixing; the natural mixed fatty alkanol and carrier mixing technology is utilized, and through the step-by-step synergistic technical means, the technical problems that existing single octacosanol is high in cost, single in effect, uneven in mixing with feed and poor in dispersity in water are solved, so that the comprehensive biological activity of the additive is remarkably improved.