73 results about "Molecular property" patented technology

A transdermal delivery system (TDS) for use in treatment of living bodies may be applied as an open (liquid, gel) or closed (patch) article. The TDS is composed of a particular active agent which dictates an associated selection of certain solvents, solvent modifiers, solute modifiers and skin stabilizers with which the medicament forms a true solution that rapidly crosses the skin barrier. The associated selection of the particular solvents, solvent modifiers, solute modifiers and skin stabilizers is based on a balancing of the molecular properties of all the components against the molecular properties of all the components plus the particular active agent. The TDS may also include a source of cellular energy to induce CAMP or cGMP. The TDS improves delivery of active agents having a molecular weight greater than 340 Daltons and increases dosage above 0.25 mg / day for such active agents.

Methods and articles of manufacture for modeling molecular properties using data regarding the partial orderings of compound properties, or by considering measurements of compound properties in terms of partial orderings are disclosed. One embodiment provides for constructing such partial orderings from data that is not already in an ordered form by processing training data to produce a partial ordering of the compounds with respect to a property of interest. Another embodiment of the invention may process the modified training data to construct a model that predicts the property of interest for arbitrary compounds.

Electronic circuits based on molecular transistors, generally used in place of semiconductors. More particularly, the invention relates to a unique method of wiring of a three-terminal molecule (or an aggregate thereof) to serve as an electronic transistor, containing a gate electrode, a source electrode, and a drain electrode. The source electrode and drain electrode are fabricated from one metal and the gate electrode is fabricated from another metal. The usage of molecular properties in this context provides significant advantages over the fabrication methods of the prior art.

Method, apparatus, and article of manufacture for modeling the biological effects of a molecule are disclosed. A machine learning application may be configured to process a set of training examples regarding a biological property of interest. Once trained, the machine learning application may be configured to generate a prediction regarding a property of interest for a test molecule. Embodiments of the invention provide a meta-model configured to generate a biological effect prediction for a molecule based on the predictions generated for the test molecule by a plurality of molecular property models.

The invention discloses a phosphaphenanthrene structure and vinyl containing-hyperbranched polysiloxane and a preparation method thereof. The preparation method comprises the steps of evenly mixing distilled water with vinyl-containing trialkoxysilane, dropwise adding catalyst slowly under the stirring condition, and increasing temperature to 50-60 DEG C, thus obtaining vinyl-containing hyperbranched polysiloxane; and mixing the vinyl-containing hyperbranched polysiloxane with 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide, adding initiator and alcohol solvent, increasing temperature to 95-100 DEG C, and carrying out purification, filtering, reduced pressure distillation and vacuum drying after reaction is finished, thus obtaining phosphaphenanthrene structure and vinyl containing-hyperbranched polysiloxane. The phosphaphenanthrene structure and vinyl containing-hyperbranched polysiloxane integrates molecular properties of hyperbranched polysiloxane, 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide and vinyl, thus having wide application prospects on polymer modification aspect. The preparation method adopted has the advantages of wide applicability and simple operation process.

The present invention provides a method of standardization of chemical and therapeutic properties and quality of foods and medicines. The present invention provides a method of chromatographic finger printing facilitating correlation of traditional methods used for chemical and therapeutic standardization of medicines and humors in the living things with physico chemical properties of the medicines and their constituents. The method is used for the qualitative and quantitative analysis of the energy involved in the medicines and living things and to understand various bio chemical reactions in living things using an energy system. It provides a rational basis to understand the traditional methods of assessment of chemical and therapeutic qualities of materials used for the said purpose. The present invention also provides the influence, of factors like pH, temperature, viscosity and ionic nature of the media along with atomic and molecular properties indicating the chemical and therapeutic values of the foods and medicines of natural and synthetic nature. The analysis of biological samples like blood indicated the utility of the method for the assessment of clinical pathological conditions of healthy and diseased. This facilitates for a better drug discovery, drug monitoring, drug targeting and drug profiling using different features of 3-D animated energy box created after analyzing the sample by different analysis, separation and detection methods.