The invention discloses an airway simulation, organ and nerve block puncture simulation human body training model which belongs to the field of medical devices. The model comprises a head part (1) composed of an eye nose part, an oral cavity part and a skull part, a neck part composed of a neck front part and a neck back part, a chest part (2) composed of a clavicle part, a chest front part, a thoracic vertebra part and a chest back part, an abdomen part which is located on the lower end of the chest part and is composed of upper, middle and lower abdomen parts, a pelvis part and a lumbosacral part, two upper limb parts (3) composed of a shoulder part, humerus parts, elbow parts, radius and ulna parts, wrist parts and hand parts, and two lower limb parts (4) composed of a groin area, hip parts, femoral parts, popliteal fossa parts, tibia and fibula parts, ankle parts and foot parts. The model can be effectively used for clinical simulation exercises, can be used for simulation puncture before the clinical treatment of a true patient, and has the advantages of convenient teaching and good use effect. Suffering of the patient can be reduced.