79 results about "Positron emission tomographic imaging" patented technology

A positron emission tomography detector for a multilayer scintillation crystal comprises a plurality of layers of scintillation crystals, a photoelectric detector system and an algorithm system, wherein the multilayer scintillation crystals comprises n layers of array scintillation crystals and m layers of continuous scintillation crystals, both n and m are integers which are greater than or equal to 1, the sum of n and m is smaller than or equal to 10, the array scintillation crystals are formed by arraying strip-type scintillation crystals along the width and length directions, the continuous scintillation crystals are scintillation crystals which have uncut inner parts, the array scintillation crystals and the continuous scintillation crystals are sequentially coupled along the height direction of the strip-type scintillation crystals to form the multilayer scintillation crystals, and the bottoms of the continuous scintillation crystals are coupled with the photoelectric detector system. The positron emission tomography detector can more accurately obtain the position and the time of energy deposition of gamma photon in the scintillation crystal, and has higher detection efficiency of the gamma photon, the spatial resolution, the time resolution and the flexibility of a positron emission tomographic imaging system can be improved when the positron emission tomography detector is applied to the positron emission tomographic imaging system, and further, the imaging quality of the system can be improved.

Disclosed is an imaging system and method for the non-pure positron emission tomography (NPET). The NPET comprises a PET subsystem to detect the annihilated photons, and a SPECT subsystem to detect the associated gamma. These two subsystems are connected by a triple coincidence circuit. The source position can be determined through detection of the three photons using the triple coincidence circuit. As long as these three photons are simultaneously detected and their energies are right, the source position is directly calculated and located on the intersection of an associated line and an annihilated line. The present invention provides good temporal resolution and quantitative analysis. It immunes to scatter and random events and achieves a high signal-to-noise ratio. Real imaging is also possible in the NPET system.

The invention relates to a special HF antenna arrangement for a combined MR-PET device. The HF antenna device has a first part (8a), which is installed fixedly with the equipment in the inspection tunnel (11) so that it is arranged below the couch (2) when the couch (2) is driven in; The HF antenna device also has a second part (8b), which can be placed on the couch (2) and can move into and out of the inspection tunnel (11) along with the couch, wherein the internal HF The second part (8b) of the antenna arrangement is designed rigidly and has a clear cross section (d) adapted to the cross section of the object to be examined (3). As a result, the time outlay for installing the RF antenna is reduced and a correction of the gamma ray attenuation is made possible by the fixed state of the RF antenna. Furthermore, a plurality of second parts (8b) having different diameters may be provided.

A method is disclosed for determining an attenuation map for use in positron emission tomography and for the use of homogeneity information relating to the magnetic resonance magnetic field, in particular for the purpose of determining shim settings, within the scope of a single magnetic resonance image recording. In at least one embodiment of the method, a first and a second image data record are firstly recorded with a three-dimensional gradient echo sequence during a first and a second echo time, respectively, with the phase difference between the water and the fat signal amounting to zeroduring the first echo time and amounting to 180 degrees during the second echo time. The attenuation map is determined from fat/water ratios obtained from the image data records by way of a Dixon technology, in particular a 2-point Dixon technology. In at least one embodiment, all voxels with a signal intensity below a first threshold value are excluded at least for the second image data record by using a mask and only the non excluded voxels of the first and second image data record are taken into consideration in order to determine the homogeneity information from the phase differences of adjacent voxels.

The invention discloses a multi-modal in-vivo imaging system for small animals and a small animal imaging method. The multi-modal in-vivo imaging system for small animals comprises a bracket, the bracket comprises a carrying bed system and a bracket system, the bracket system is provided with a rotary disc, and the carrying bed system is located in the axial direction of the rotary disc; the rotary disc is provided with reflector devices of an X-ray computer tomography subsystem, a positron emission tomography subsystem and an optical subsystem; the optical subsystem comprises a bio-luminescence tomography optical subsystem, a fluorescence molecular tomography optical subsystem and an optical camera, and the optical camera is mounted on the carrying bed system; the imaging view of the X-ray computer tomography subsystem, the imaging view of the positron emission tomography subsystem and the imaging view of the optical camera are at least overlapped partially; the carrying bed system further comprises an animal carrying bed, and the animal carrying bed is used for moving small animals to the overlapped region of the views.

The present invention provides a device for superposed magnetic resonance and positron emission tomography imaging. The device includes a gradient coil and a positron emission tomography unit (PET unit). The PET unit is arranged within the gradient coil and has a first shield against radiofrequency radiation which in part surrounds the PET unit, and a second shield against radiofrequency radiation is arranged on the gradient coil. The first shield is connected to the second shield to form a shield which is at least partly closed. This makes a closed shield for the PET unit possible, which nevertheless is still easily accessible for maintenance purposes due to the two-part design of the shield.

The invention provides a positron emission tomography device and method. The device comprises a detector system module and a computer system module which are detachably connected. The detector system module comprises a clock module, a detector, a switch and a power source; according to the computer system module, a detector configuration module and the detector are in detachable communication connection so as to perform parameter configuration on the detector; the input end of an imaging information obtaining module and the switch are in detachable communication connection so as to receive imaging information data; a pulse information analysis and processing module and the imaging information obtaining module are in communication connection so that the imaging information data can be converted into pulse time, energy and position information; a coincidence event screening module and the pulse information analysis and processing module are in communication connection and the pulse time, energy and position information can be converted into coincidence event pair information; an image rebuilding module performs image rebuilding. The device and method are applicable to a PET imaging system meeting any individual requirement, and rapid imaging for specific applications can be achieved at any time and any place.

The invention discloses a positron emission tomography ray detector, which comprises a scintillator array, an optical fiber or optical fiber bundle and a photomultiplier tube, wherein the scintillator array consists of a plurality of independent scintillator units, works in an MRI (Magnetic Resonance Imaging) magnetic field, and is used for receiving radioactive rays and sending out flare light; one end of the optical fiber or optical fiber bundle is connected to the scintillator array, and receives and transmits the flare light sent out by the scintillator array; and the other end of the optical fiber or optical fiber bundle is connected with the photomultiplier tube, and the optical fiber or optical fiber bundle has the length so that the photomultiplier tube is positioned outside the MRI magnetic filed area and far away from the MRI magnetic field. By the structure, the combination of PET (Position-Emission Tomography) and MRI is simply realized, electromagnetic interference between the PET and the MRI is effectively removed, and a larger leeway is left on the integral mechanical structure.

The invention discloses a positron emission tomography photon detecting device comprising a detection array which is formed by multiple detection units; the detection array comprises at least one scintillator device; and at least one photoelectric converter is coupled to each scintillator device; each photoelectric converter is connected with an energy signal readout circuit and a time signal readout circuit for detecting events. The photon detecting device of the invention has the advantages of precise time detection and low cost.

The invention provides a method and a device for detecting the flight time performance of a positron emission tomography system. The method comprises the following steps: performing data acquisition on detected objects distributed according to an activity rule by using a system; performing a back projection operation with flight time information on acquired data to obtain first back projection data; performing a back projection operation without the flight time information on the acquired data to obtain second back projection data; comparing the first back projection data with the second back projection data, and acquiring the flight time performance of the system according to comparison data. By adopting the method and the device, the flight time performance of the system can be detected conveniently and efficiently.

The invention discloses a full-digital electronic system of a full-digital processing device, and relates to the technical field of medical imaging, in particular to the field of positron emission tomography (PET). The full-digital electronic system comprises a plurality of original event detection modules with the same number as detectors which are arranged in an annular array form, a system event sorting device, a system event transmitting device, and a power supply and a clock control device which are provided for the original event detection modules, the system event sorting device and the system event transmitting device, wherein each original event detection module is connected to the corresponding detector through an analog/digital (A/D) converter; and the output end of each original event detection module is connected to the input end of the system event transmitting device through the system event sorting device. The full-digital electronic system can meet the requirement of the full-digital processing device of a full-digital processing PET electronic system.

The invention relates to a crystal position chart establishment method which comprises following steps of (1) utilizing a morphological method to conduct preprocessing for a two-dimensional position scatter diagram; (2) distinguishing top points of the two-dimensional position scatter diagram; (3) judging correctness of the top points which are distinguished in the step (2), if the top points which are distinguished in the step (2) are all correct, the top points enter into a step (4) and the top points which are distinguished in the step (2) have errors, the mistaken top points are corrected manually and then enter into the step (4); (4) conducting classification for the top points according to lines; (5) completing calculating of all middle points according to coordinates of an upper top point, a lower top point, a left top point and a right top point, the upper top point, the lower top point, the left top joint and the right top joint are sequentially adjacent in each adjacent two lines; (6) respectively conducting curve fitting for all the middle points in a line and column mode, and completing partitioning of the two-dimensional position scatter diagram. The crystal position chart establishment method can be widely applied to the crystal position chart establishing process of a positive electron emission tomography system.

The invention discloses a positron emission tomography detector module and relates to the technical field of positron emission tomography detectors. The positron emission tomography detector module comprises three to five detector encapsulation units, wherein the detector encapsulation units are formed along an axial array. Each detector encapsulation unit is mainly composed of two detector units and a wedge-shaped installing plate. According to the positron emission tomography detector module, the wedge-shaped installing plate can be used for encapsulating the two detector unit in a left and right arrangement to form a detector encapsulation unit. And then, a locating pin hole can be used for precisely locating an adjacent detector module. After that, bolts can be used for forming the three to five detector encapsulation units along the axial array to form the detector module. When one of the detector units appears problems, the troubled detector encapsulation unit can be just replaced to reduce the replacing numbers of the detector units at the time of maintaining and save the maintaining cost. When a detector system is updated, the corresponding number of the detector encapsulation units can be added according to updating requests.

The present invention relates to a combined positron emission tomography-magnetic resonance imaging apparatus, which comprises a positron emission tomography apparatus (3) having at least one radiation detector (4), and a magnetic resonance imaging apparatus having at least one gradient coil (6) and a high-frequency antenna device (8). In order to prevent mechanical vibration being induced in the PET gantry by the gradient coil, the combined position emission tomography-magnetic resonance imaging apparatus according to the present invention is developed in that a first molding part (7) is provided, the surface of which coincides with the inner shell (9) of the at least one gradient coil (6), and a second molding part (10) is provided, the surface of which coincides with the outer shell (11) of the radiation detector (4), the distance between the two shells (9, 11) is virtually constant over the circumference of the shells, and a vacuum seal (13) is respectively arranged along at least a first circumferential line and a second circumferential line such that a closed cavity is formed between the vacuum seals.

The invention belongs to the field of nano-medicine and molecular imaging, and particularly relates to a fluorescent carbon dot for labeling of radionuclide iodine, a synthetic method of the fluorescent carbon dot and application in tumor imaging. The carbon dot is synthesized in one step and can be directly labeled with radionuclide iodine. A labeled product has excellent radiochemical stability and physicochemical stability and can be directly used for 124I-based PET (positron emission tomography), SPECT(125I-based single-photon emission computed tomography) imaging and 131I radiotherapy of a tumor region. The synthetic method of the fluorescent carbon dot is simple, price of raw materials is low, fluorescence efficiency is high, and biocompatibility is good; the fluorescent carbon dot has the advantage of rapid metabolism in vivo like small molecules, and can also be well enriched in the tumor region by effects of high permeability and long retention of nanoparticles to diagnose and treat a tumor.

The invention discloses a primitive event detection module for an all-digital processing unit, relating to the technical field of medical imaging, in particular to the field of positron emission tomography. The primitive event detection module disclosed by the invention is provided with a device, which can judge whether the position and time signal of a gamma photo-event captured by detectors belongs to a valid event by using arrival time triggering and energy discrimination, and if so, latches the position and time signal of the gamma photo-event according to the format of the primitive gamma photo-event characters and outputs the position and time signal. The invention can satisfy the demands for the all-digital processing unit in an all-digital processing positron emission tomography electronic system.

The invention provides a positron emission tomography (PET) system and an image reconstruction method thereof. The PET system comprises a plurality of detector units arranged in the axial direction, and a plurality of coincidence logic circuits. Each detector unit is suitable for generating multiple single event counts; each coincidence logic circuit is connected to one or more corresponding detector units, wherein single event data generated by each detector unit is sent to the corresponding coincidence logic circuit, and the coincidence logic circuits generate coincidence counts of the detector units in parallel.

The invention discloses an image-forming method of weighting curvature flow filtering during the least square iterating for constructing image of positive electron emitting tomography, firstly getting observing data, determining the scale of original image, comparing each component in the observing data with 1, dividing each component in the error variance and filtering the intermediate image with curvature flow and getting the filtered image as original image, repeating this course until the image reconstructed image contracted and getting the finished image; the invention adding curvature flow filtering in the least square iterating depending on the current feature of PET image-forming, through which to inhibit pattern noise and improve the image quality; the invention is characterized by the simple process, fast treating speed and good effect for inhibiting the background disturb.

The invention discloses a radial detector. The radial detector comprises a resistive board chamber, a flashing body and a photoelectric cathode. The resistive board chamber comprises first electrode glass, and the photoelectric cathode is arranged on the first electrode glass. The flashing body is arranged outside the resistive board chamber. The radial detector is high in sensitivity and position resolving power, capable of strengthening quanta, low in cost and applicable to detector systems such as SPECT (single-photon emission computed tomography) and PET (positron emission tomography).