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6results about How to "Achieve attenuation" patented technology

A lead-free perovskite x-ray shielding composite material and a preparation method and application thereof

PendingCN122117501AExcellent Mechanical FlexibilityImprove toughnessShieldingPerovskite (structure)Heat stability
The application belongs to the field of new materials, and discloses a lead-free perovskite X-ray shielding composite material and a preparation method and application thereof, and comprises the following steps: mixing ANF / DMSO dispersion liquid with ethanol to obtain re-protonated ANF dispersion liquid; mixing the re-protonated ANF dispersion liquid, CsI powder and ethanol, and stirring to obtain two portions of the same CsI / ANF dispersion liquid; mixing re-protonated ANF, Cs3Bi2I9 powder and ethanol, and stirring to obtain Cs3Bi2I9 / ANF dispersion liquid; sequentially filtering the first portion of CsI / ANF dispersion liquid, the Cs3Bi2I9 / ANF dispersion liquid and the second portion of CsI / ANF dispersion liquid by using a gel-gel method, and vacuum hot-pressing to obtain a composite gradient film with a biomimetic symmetrical structure, which is used as a lead-free perovskite X-ray shielding composite material; and the application realizes continuous and efficient X-ray shielding effect, and can improve the mechanical flexibility and thermal stability of the material.
Owner:SHAANXI UNIV OF SCI & TECH

Antimony nanopowder, preparation method and application thereof

ActiveCN122076979AAddressing pulmonary toxicity issuesReduce Occupational Health RisksTransportation and packagingMetal-working apparatusPulmonary effectsChemical reaction
This invention relates to antimony nanopowder, its preparation method, and its applications, belonging to the field of metal powder processing technology. The method includes dispersing antimony nanopowder in a solvent to obtain a dispersion, mixing the dispersion with 5-10 times the mass of nitrobenzene diazonium salt (p-NBD) of the antimony nanopowder, and reacting under light irradiation at 0-4°C for 30-60 hours to obtain passivated antimony nanopowder. The diazo chemical reaction forms stable covalent bonds on the surface of Sb NPs, blocking their interaction with respiratory cells. Compared with the original Sb NPs group, the nitrobenzene diazonium salt modification reverses the GPX4 activity inhibition effect, upregulates GPX4 protein expression and restores it to near the control group level, and eliminates the ability to induce ferroptosis, thus addressing the pulmonary toxicity problem of Sb NPs from the perspective of ferroptosis mechanism.
Owner:SHANDONG UNIV +1

Multi-dimensional state sensing and intelligent operation and maintenance decision-making method and system for power distribution network

The invention discloses a multi-dimensional state sensing and intelligent operation and maintenance decision-making method and system for a power distribution network, and relates to the technical field of intelligent monitoring and operation and maintenance of a power system. The voltage waveform, the current jump and the power reflexed change at the moment of disconnection and reconnection of the high-power equipment are continuously recorded through high-frequency sampling, so that energy mutation fingerprints are formed. According to the method, by constructing a transient energy tracing band and an energy mutation fingerprint, millisecond-level sensing and accurate recognition of the sudden return process of the high-power equipment are achieved, an energy convergence judgment band and an antagonism threshold window are established, energy propagation is actively suppressed at the sudden return moment, and current impact is slowly released; the energy distribution of the power distribution network is controlled, the node voltage is stable, and the operation safety and the response reliability are improved.
Owner:ANHUI GRAIN ENG VOCATIONAL COLLEGE

Filamentous fungi and their use

The present application belongs to the technical field of microorganism screening, and particularly relates to a Byssochlamys sp. and application thereof, wherein the Byssochlamys sp. has a preservation number of CGMCC No. 40543. When the Byssochlamys sp. is used for solid-state fermentation of pinellia, the digestion-assisting ability of pinellia powder can be improved, the toxicity of pinellia can be reduced, the content of active components such as amino acids, alkaloids and flavones for relieving cough can be increased, and the content of anticancer components can be increased. When the Byssochlamys sp. is used for liquid-state fermentation of pinellia, compared with traditional fermentation, the total acid and the soluble solids can be increased. Meanwhile, the Byssochlamys sp. is stable in fermentation, and can also be used for preparing feed containing a mint fragrance.
Owner:川北医学院附属医院 +1

293H cell line and MDCK cell line for expressing influenza virus PB1 gene and application

PendingCN121852326Aachieve attenuationImplement insertionSsRNA viruses negative-senseTransferasesMicroorganismBioinformatics
The invention relates to the field of biology, and particularly provides a 293H cell line for expressing an influenza virus PB1 gene, the cell line is classified and named as an HEK-293H cell line, and the preservation number is GDMCC NO: 66761. The preservation date is July 25, 2025, and the strain is preserved in the Guangdong Microbial Culture Collection Center, and the preservation address is the 5th floor of the Experimental Building, No. 100 Courtyard, Middle Xianlie Road, Guangzhou District, Guangdong Province. In addition, the invention also provides an MDCK cell line for expressing the influenza virus PB1 gene, both the MDCK cell line and the MDCK cell line can express PB1 protein, and rescue and propagation of the PB1 gene knockout (PB1-KO) replication defective influenza virus can be realized. Meanwhile, the invention also discloses application of the two cell lines.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT) +3

Trabectedin nano-micelle and oxaliplatin-loaded drug combination composition and application of trabectedin nano-micelle and oxaliplatin-loaded drug combination composition

PendingCN121971451AImprove delivery behavior in vivoImprove passive target enrichment capabilitiesOrganic active ingredientsDigestive systemTherapeutic effectPharmaceutical Substances
The invention discloses a trabectedin-loaded nano-micelle and oxaliplatin-loaded drug combination composition and application, and relates to the technical field of delivery and drug combination, and the trabectedin-loaded nano-micelle and oxaliplatin-loaded drug combination composition comprises trabectedin-loaded nano-micelle and oxaliplatin. The invention also discloses an application of the combined pharmaceutical composition in preparation of antitumor drugs. According to the invention, a pH-sensitive amphiphilic biodegradable material (such as PCL-PEOz) and a chemical drug are self-assembled to form stable micelles, so that the bioavailability of the drug is improved, the critical concentration of the micelles is reduced, and long-acting circulation in vivo is realized; the system can be combined with oxaliplatin for use, so that the sensitivity of tumor cells to oxaliplatin is promoted, the synergistic effect of chemotherapy and immunotherapy is exerted, the treatment effect of malignant tumors is improved, and the tumor microenvironment is improved.
Owner:SHANGHAI JIAOTONG UNIV