The invention discloses a disk brake cylinder assembly with a parking mechanism and a brake caliper. The disk brake cylinder assembly comprises a cylinder block, a piston, a travel adjusting threaded sleeve, a travel adjusting threaded rod, a steel ball, a drive shaft, a plane sliding bearing, an O-shaped seal ring and a spring resetting device. One end of the travel adjusting threaded rod is provided with a multi-head saw-tooth thread. The other end of the travel adjusting threaded rod is a ball disk with slope rolling ways. Arc-shaped guide bosses are evenly distributed on the outer edge of the ball disk, and the bosses are matched with grooves in a cylinder hole and prevent the travel adjusting threaded rod from rotating. The travel adjusting threaded rod has good centering performance, and therefore an auxiliary piston having the centering function in the piston is omitted. By the adoption of the disk brake cylinder assembly with the parking mechanism, the movement type of parts of the parking mechanism is simplified, and the risk that multiple leaking points exist in existing known structures is avoided. The disk brake cylinder assembly with the parking mechanism is simple in structure and higher in safety performance, the parts can be more easily machined, the transmission efficiency of the parking brake force is improved, and low cost, high performance and higher safety performance are effectively combined.