The invention discloses a method for realizing high voltage of a monomer battery, preparation of a monomer battery and a battery pack manufacturing method of the monomer batteries. The high-voltage monomer battery comprises a positive plate (3), a diaphragm (4), a negative plate (6), a diaphragm (4), ..., a positive plate (3), a diaphragm (4), a negative plate (6), a diaphragm (4) and a monomer battery flexible package membrane (8), wherein the diaphragms (4) are arranged between the positive plates (3) and the negative plates (6) in a spacing manner, and space the negative plates (6) and thepositive plates (3) in sequence; an aluminum plastic membrane (shell) is wrapped on the outermost side; a positive electrode comprises a positive electrode current collector and an active substance Alayer; the active substance A layer is prepared from 95.0 to 99.0 percent of an active substance A, 0.5 to 3.0 percent of a conductive agent and 0.5 to 2.0 percent of an adhesive; a negative electrodecomprises a negative electrode current collector and an active substance B layer; the active substance B layer is prepared from 95.0 to 99.0 percent of an active substance B, 0.5 to 2.0 percent of aconductive agent, 0 to 1.0 percent of a thickening agent and 0.5 to 3.0 percent of an adhesive. The monomer battery disclosed by the invention is high in voltage, and relatively high in volume energydensity and rate performance.