The invention relates to a double-cavity five-channel first-aid respirator for respiratory alkaline poisoning, and aims to solve the technical problem that an existing respirator cannot solve the problem that oxygen deficit and respiratory alkaline poisoning exist at the same time. According to the technical scheme, the double-cavity five-channel first-aid respirator comprises a cylinder body, a first partition plate, a top plate, a rotating shaft, a ventilation cover and a second partition plate, a mask and a detection module interface are arranged at the lower end of the cylinder body, the first partition plate is vertically arranged in the middle of an inner cavity of the cylinder body, and an oxygen interface is formed in the portion, located on the lower portion of an area I, of the cylinder body, the top plate is arranged on the upper end, the rotating shaft is arranged in the middle of the top plate, the ventilation cover is arranged on the top plate, the second partition plate is vertically arranged in the middle of the ventilation cover, a ventilation cover bottom plate is arranged on the lower portion in the ventilation cover, a first air adjusting opening and a second air adjusting opening are formed in the top plate and the ventilation cover bottom plate, and a plurality of ventilation holes are evenly formed in the side walls of the two sides and the rear side of the ventilation cover. According to the invention, the inhalation concentration of carbon dioxide of a patient can be increased, oxygen can be supplemented, and the problems of respiratory alkaline poisoning and oxygen deficit can be solved.