The invention relates to an ultra-high pressure extraction method of asparagus saponin, which belongs to the technical field of natural products. The process of the present invention includes the steps of raw material treatment, drying and crushing, degreasing, ultra-high pressure extraction, separation and purification, and vacuum evaporation. Mainly by optimizing and improving the ultra-high pressure extraction step, the ultra-high pressure extraction technology combined with the macroporous resin adsorption technology is applied to asparagus The production of saponins effectively solves the technical difficulties in the production of asparagus saponins, so that the produced saponins have the characteristics of high safety, not easy to absorb moisture, good wettability, strong spreadability, excellent adhesion, etc., and the extraction time is short, High extraction efficiency, low energy consumption, low extraction temperature, high activity of active ingredients, environmental protection and no pollution, can effectively extract asparagus saponins in asparagus plants and scraps, and can also extract amino acids in asparagus plants and scraps.